Orthopedic Infections-Clinical Applications of Intravenous Regional Limb Perfusion in the Field.
- Journal Article
- Review
Summary
The research article covers the clinical applications of a technique called intravenous regional limb perfusion in treatment of orthopedic infections in horses, which is a common occurrence in equine veterinary practice.
Introduction
This article presents a comprehensive review of intravenous regional limb perfusion (IVRLP), a procedure widely used by equine veterinarians to treats orthopedic infections in horses, a common ailment in this species. It delves into its clinical applications and provides an overview of the technique.
Orthopedic Infections in Horses
- Orthopedic infections are a frequent issue in equine medicine, often arising from traumatic wounds on the distal limb and penetrating injuries in the hoof.
- These infections can have serious implications for the health and performance of the horse and are therefore of significant concern for both owners and veterinarians.
Intravenous Regional Limb Perfusion (IVRLP)
- IVRLP is a treatment technique extensively used to manage orthopedic infections in horses.
- The process involves injecting a high concentration of antibiotics directly into the blood vessels of the affected limb, allowing for a direct attack on the infectious agents at the source.
- The IVRLP technique is particularly useful for treating infections in areas with limited blood supply and when high systemic doses of antibiotic treatment would be harmful or ineffective.
Clinical Applications
- The article reviews several clinical applications of the IVRLP technique, providing insight into its efficacy in different scenarios, especially in field conditions.
- The primary focus is on treating infections arising from traumatic wounds and penetrating hoof injuries, but the procedure’s potential for handling other orthopedic conditions is also discussed.
Technique Overview
- The article offers a technique overview for IVRLP which is a guide for the veterinarians using this procedure.
- While it may not delve into the specifics, this overview gives practitioners a fundamental understanding of how the procedure works and how it can be applied in their own practice.
Overall, this research article provides a comprehensive understanding of IVRLP’s clinical applications and offers critical guidance for practitioners looking to implement it in the field.
Cite This Article
Publication
Researcher Affiliations
- Department of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, One Shields Avenue, Davis, CA 95616, USA. Electronic address: ikilcoyne@ucdavis.edu.
- Department of Surgical and Radiological Sciences, UC Davis School of Veterinary Medicine, One Shields Avenue, Davis, CA 95616, USA.
MeSH Terms
- Administration, Intravenous
- Animals
- Anti-Bacterial Agents / administration & dosage
- Foot Diseases / therapy
- Foot Diseases / veterinary
- Hoof and Claw / injuries
- Horse Diseases / therapy
- Horses
- Orthopedic Procedures / veterinary
- Perfusion / veterinary
Conflict of Interest Statement
Citations
This article has been cited 1 times.- Guillot M, Mespoulhes-Rivière C, Bousquet-Mélou A, Lacroix MZ, Roques BB, Lallemand EA. Pharmacokinetics, pharmacodynamics, and local tolerance at injection site of penicillin and gentamicin administered by intravenous regional limb perfusion in standing horses: comparison between weightbearing and flexed limbs. BMC Vet Res 2025 Nov 7;21(1):650.