Osteomyelitis in horses.
Abstract: Much has been learned in the past decade about osteomyelitis. The inhibitory mechanisms of the "biofilm slime" layer that is formed by bacterial extracapsular exopolysaccharides and binds to bone, joints, and implants are now better understood than in the past. The surface colonization of bacteria that occurs within these biofilms is a biologic phenomenon that is somewhat unique to orthopedic infections. This survival strategy of bacteria is effective, and it is important for veterinarians who treat osteomyelitis to be aware of current diagnostic and therapeutic treatment modalities. The practitioner should be aware of the most common bacteria associated with osteomyelitis and the traditional treatments that are still used. Current therapeutic treatment modalities, such as antibiotic- impregnated polymethylmethacrylate, antibiotic-impregnated plaster of Paris, and regional perfusion, have become routine, however, and have been responsible for improving the prevention and outcome of osteomyelitis in the horse. It is the intent of this article to make equine veterinarians aware of current information as well as the future treatments of osteomyelitis.
Publication Date: 2006-08-03 PubMed ID: 16882481DOI: 10.1016/j.cveq.2006.04.001Google Scholar: Lookup
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Summary
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The research paper provides an overview of the recent advancements in the understanding and treatment of osteomyelitis, a bone infection, in horses. This includes insights into the survival strategies of infection-causing bacteria, common bacteria responsible for osteomyelitis, traditional and current treatment methods, and future possibilities of osteomyelitis management.
Understanding Biofilm Slime
- In the last decade, understanding of osteomyelitis has greatly improved. One key focus of this paper is the “biofilm slime”—an extracapsular layer created by bacteria which adheres to bone, implants, and joints. This layer is difficult to break down or inhibit, allowing the bacteria to survive effectively.
- Surface colonization is a process by which bacteria multiply over the surface of the biofilm. This type of infection profile is unique to orthopedic infections like osteomyelitis.
Diagnostic and Therapeutic Treatment
- With the advanced understanding of bacterial survival strategies, improved diagnostic and therapeutic treatment procedures have been introduced. These methods can help veterinarians reliably identify and treat osteomyelitis in horses.
- The paper emphasises the need for practitioners to keep abreast with not only the most common bacteria associated with the disease but also the traditional treatments that are still effectively used.
- Furthermore, veterinarians are encouraged to adapt to newer treatment modalities such as antibiotic-impregnated polymethylmethacrylate, antibiotic-impregnated plaster of Paris, and regional perfusion therapies. These method shave become routine and contribute significantly to the prevention and improved prognosis of osteomyelitis in horses.
Looking at the Future
- Finally, the article mentions that it aims to raise awareness among equine veterinarians about the current research and knowledge in osteomyelitis treatment.
- With increasing understanding of the disease and improving technologies, it is crucial for practitioners to stay updated with evolving treatment practices and methodologies for effective disease management in the future.
Cite This Article
APA
Goodrich LR.
(2006).
Osteomyelitis in horses.
Vet Clin North Am Equine Pract, 22(2), 389-ix.
https://doi.org/10.1016/j.cveq.2006.04.001 Publication
Researcher Affiliations
- College of Veterinary Medicine, Colorado State University, 300 West Drake Road, Fort Collins, CO 80523, USA. laurie.goodrich@colostate.edu
MeSH Terms
- Animals
- Anti-Bacterial Agents / administration & dosage
- Anti-Bacterial Agents / therapeutic use
- Bone Transplantation / veterinary
- Curettage / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / microbiology
- Horse Diseases / therapy
- Horses
- Osteomyelitis / diagnosis
- Osteomyelitis / microbiology
- Osteomyelitis / therapy
- Osteomyelitis / veterinary
- Perfusion / veterinary
- Postoperative Complications / veterinary
- Therapies, Investigational / veterinary
Citations
This article has been cited 2 times.- Mizuguchi Y, Kato A, Aizu M. Regional antibiotic perfusion through the lateral saphenous vein in two horses with septic calcaneal osteitis.. J Vet Med Sci 2023 Jan 6;85(1):55-61.
- Larsen EA, Lack AC, Wassack E. Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess.. Front Vet Sci 2022;9:783753.
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