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Outbreak of acute colitis on a horse farm associated with tetracycline-contaminated sweet feed.

Abstract: Exposure of a group of horses to tetracycline-contaminated feed resulted in acute colitis and subsequent death in one horse and milder diarrhea in 3 others. The most severely affected animal demonstrated clinical and pathological findings typical of colitis X. The other herdmates responded well to administration of zinc bacitracin.
Publication Date: 1999-11-26 PubMed ID: 10572668PubMed Central: PMC1539814
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Summary

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This research article investigates an outbreak of acute colitis among a group of horses following their exposure to tetracycline-contaminated feed, resulting in severe symptoms in one horse and milder ones in others.

Research Context

  • The research was conducted following an outbreak of acute colitis on a horse farm which was linked to exposure of feed contaminated with Tetracycline.
  • The contamination resulted in serious illness, showing clinical and pathological signs typical of Colitis X in the most severely affected horse, and milder symptoms of diarrhea in three others.

Data Collection

  • Data used in this research were based on the observed symptoms and the response of the horses to the contaminated feed and subsequent treatments.
  • Diagnostic and histopathological assessments were likely utilized to establish and confirm the presence of Colitis X in the severely affected horse.

Findings

  • The research findings affirmed that dietary contamination played a significant role in the outbreak. Specifically, the presence of Tetracycline in the feed led to the development of acute colitis.
  • The most severely affected horse not only exhibited symptoms of acute colitis, but also demonstrated clinical and pathological findings typical of Colitis X, which can be lethal if not treated promptly.

Treatment and Outcome

  • To treat the disease, the administration of Zinc Bacitracin was employed on the less severely affected horses, which they responded well to. This might suggest Zinc Bacitracin could be effective in treating initial stages or milder cases of colitis.
  • However, the paper did not provide detailed information on the treatment and survival of the most severely affected horse that exhibited symptoms of Colitis X.

Conclusion

  • The study adds to the body of knowledge confirming Tetracycline’s potential to induce colitis when used inappropriately or accidentally ingested in contaminated feed.
  • It highlights the importance of proper veterinary pharmaceutical management and the need to prevent such contaminations to protect animal health.

Cite This Article

APA
Keir AA, Stämpfli HR, Crawford J. (1999). Outbreak of acute colitis on a horse farm associated with tetracycline-contaminated sweet feed. Can Vet J, 40(10), 718-720.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 40
Issue: 10
Pages: 718-720

Researcher Affiliations

Keir, A A
  • Department of Clinical Studies, Ontario Veterinary College, University of Guelph.
Stämpfli, H R
    Crawford, J

      MeSH Terms

      • Acute Disease
      • Animal Feed
      • Animals
      • Anti-Bacterial Agents / poisoning
      • Colitis / pathology
      • Colitis / veterinary
      • Diarrhea / etiology
      • Diarrhea / veterinary
      • Fatal Outcome
      • Food Contamination
      • Horse Diseases / chemically induced
      • Horses
      • Male
      • Tetracycline / poisoning

      References

      This article includes 11 references
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