Outcome of treatment in 35 cases of guttural pouch mycosis.
Abstract: This paper describes the outcome of treatment of 30 cases of guttural pouch mycosis by ligation of the internal carotid artery on the cardiac side of the lesion and lavage of the affected pouch with natamycin. Twenty-three horses recovered fully following this treatment while laryngeal hemiplegia persisted in one case and slight dysphagia caused by pharyngeal hemiplegia in another. The remaining five horses died or were destroyed. Five horses with guttural pouch mycosis, which had shown no epistaxis but had pharyngeal hemiplegia, were treated by topical natamycin alone. Only two of these survived, of which one remained slightly dysphagic. Ligation of the internal carotid artery of the cardiac side of the lesion is an effective means of reducing the chance of fatal epistaxis in cases of guttural pouch mycosis. Some cases of pharyngeal hemiplegia can make a complete recovery although it may take 12 to 18 months.
Publication Date: 1987-09-01 PubMed ID: 3500040DOI: 10.1111/j.2042-3306.1987.tb02649.xGoogle Scholar: Lookup
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- Journal Article
Summary
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The research paper examines the results of treating 30 horses with guttural pouch mycosis using a specific medical procedure. The majority of the horses made a full recovery, though there were some complications, and a few horses did not survive.
Research Methodology
- The study focuses on the treatment of guttural pouch mycosis in horses. Guttural pouch mycosis is a fungal infection found in horses that can be dangerous if left untreated.
- The researchers used a treatment method that involved the ligation of the internal carotid artery on the heart side of the lesion and the washing of the infected pouch with a drug called natamycin.
- 30 horses suffering from this illness were part of the study. Aside from the main group, another sample of five horses, also afflicted with the disease but showing no symptoms of nosebleeds, were only treated with natamycin.
Results and Observations
- Out of the 30 horses in the main study, 23 showed complete recovery after the treatment.
- One horse showed persistent symptoms of laryngeal hemiplegia – paralysis on one side of the larynx, while another showed mild difficulty swallowing due to pharyngeal hemiplegia, a similar paralysis but located in the pharynx.
- The rest, totalling 5, did not survive the treatment and passed away or had to be euthanised.
- As for the group of five horses treated only with natamycin, two survived the procedure but one of them still displayed some difficulty swallowing.
Conclusion and Implications
- The study concludes that ligation of the internal carotid artery on the heart’s side of the lesion is an effective method to decrease the risk of fatal nosebleeds in horses suffering from guttural pouch mycosis.
- It also points out that some cases of pharyngeal hemiplegia can fully recover, although it could take 12 to 18 months for the horse to regain its normal functions.
Cite This Article
APA
Greet TR.
(1987).
Outcome of treatment in 35 cases of guttural pouch mycosis.
Equine Vet J, 19(5), 483-487.
https://doi.org/10.1111/j.2042-3306.1987.tb02649.x Publication
Researcher Affiliations
- Beaufort Cottage Stables, Newmarket, Suffolk.
MeSH Terms
- Administration, Topical
- Animals
- Carotid Artery, Internal / surgery
- Eustachian Tube
- Female
- Horse Diseases / surgery
- Horse Diseases / therapy
- Horses
- Ligation / veterinary
- Male
- Mycoses / surgery
- Mycoses / therapy
- Mycoses / veterinary
- Natamycin / administration & dosage
- Natamycin / therapeutic use
- Otorhinolaryngologic Diseases / surgery
- Otorhinolaryngologic Diseases / therapy
- Otorhinolaryngologic Diseases / veterinary
Citations
This article has been cited 7 times.- Lepage OM. Guttural Pouch Mycosis: A Three-Step Therapeutic Approach. Vet Sci 2024 Jan 19;11(1).
- Caffey SR, Lund CM, Farnsworth KD, Fransson BA, Ragle CA. Effects of head position on internal and external carotid pressures in standing sedated horses. Can J Vet Res 2021 Apr;85(2):127-130.
- Elad D. Therapy of Non-Dermatophytic Mycoses in Animals. J Fungi (Basel) 2018 Oct 30;4(4).
- Elad D, Segal E. Diagnostic Aspects of Veterinary and Human Aspergillosis. Front Microbiol 2018;9:1303.
- Whitehead AE, Whitty J, Scott M, Léguillette R. Reversible dysphagia secondary to guttural pouch mycosis in a gelding treated medically with voriconazole and surgically with carotid occlusion and esophagostomy. Can Vet J 2018 Feb;59(2):165-170.
- Eichentopf A, Snyder A, Recknagel S, Uhlig A, Waltl V, Schusser GF. Dysphagia caused by focal guttural pouch mycosis: mononeuropathy of the pharyngeal ramus of the vagal nerve in a 20-year-old pony mare. Ir Vet J 2013;66(1):13.
- Hunter B, Nation PN. Mycotic encephalitis, sinus osteomyelitis, and guttural pouch mycosis in a 3-year-old Arabian colt. Can Vet J 2011 Dec;52(12):1339-41.
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