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Emerging infectious diseases2023; 29(9); 1941-1944; doi: 10.3201/eid2909.230049

Partial Genome Characterization of Novel Parapoxvirus in Horse, Finland.

Abstract: We report a sequencing protocol and 121-kb poxvirus sequence from a clinical sample from a horse in Finland with dermatitis. Based on phylogenetic analyses, the virus is a novel parapoxvirus associated with a recent epidemic; previous data suggest zoonotic potential. Increased awareness of this virus and specific diagnostic protocols are needed.
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Publication Date: 2023-08-23 PubMed ID: 37610155PubMed Central: PMC10461679DOI: 10.3201/eid2909.230049Google Scholar: Lookup
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  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article centres on the partial genome characterization of a newly discovered Parapoxvirus in a horse from Finland presenting dermatitis. The authors reiterate the importance of increased awareness and diagnostic protocols due to the virus’s possible transmission to humans.

Introduction

  • The research involves genetic sequencing of a novel parapoxvirus isolated from a horse in Finland suffering from dermatitis. Parapoxviruses are known for causing skin infections in both animals and humans.
  • This study emphasizes the development of a new sequencing protocol, utilized to sequence a 121-kb segment of the poxvirus.
  • Parapoxviruses have previously been linked with zoonotic potential, meaning they can transmit from animals to humans, hence raising concerns about public health.

Methods and Findings

  • The virus sequence was obtained using a recently developed sequencing protocol optimized for this study.
  • The virus sequence, consisting of 121-kb of the poxvirus sequence, was analyzed and compared to other known parapoxviruses for classification.
  • Phylogenetic analyses were carried out to categorize the virus distinctly. Phylogenetic analyses are methods used to investigate evolutionary relationships between different organisms.
  • The comparisons and phylogenetic analyses suggest the dermatitis-causing virus in the horse is a novel parapoxvirus linked to a recent epidemic.

Implications and Recommendations

  • The presence of a novel parapoxvirus raises concerns about a possible epidemic and increased risks to both animal and human health. Particular attention is needed given suggested zoonotic potential.
  • The authors highlight the need for increased awareness regarding this type of virus as well as developing specific diagnostic protocols for efficient detection and management.
  • The presence of such a virus in a horse in Finland also poses questions about geographical spread and origins of the virus, which may be addressed in further studies.

Cite This Article

APA
Virtanen J, Hautaniemi M, Dutra L, Plyusnin I, Hautala K, Smura T, Vapalahti O, Sironen T, Kant R, Kinnunen PM. (2023). Partial Genome Characterization of Novel Parapoxvirus in Horse, Finland. Emerg Infect Dis, 29(9), 1941-1944. https://doi.org/10.3201/eid2909.230049

Publication

Emerging infectious diseases
ISSN: 1080-6059
NlmUniqueID: 9508155
Country: United States
Language: English
Volume: 29
Issue: 9
Pages: 1941-1944

Researcher Affiliations

Virtanen, Jenni
    Hautaniemi, Maria
      Dutra, Lara
        Plyusnin, Ilya
          Hautala, Katja
            Smura, Teemu
              Vapalahti, Olli
                Sironen, Tarja
                  Kant, Ravi
                    Kinnunen, Paula M

                      MeSH Terms

                      • Horses
                      • Animals
                      • Parapoxvirus / genetics
                      • Finland / epidemiology
                      • Phylogeny
                      • Poxviridae
                      • Communicable Diseases

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                      Citations

                      This article has been cited 1 times.
                      1. Pettersson J, Levanov L, Tervo S, Hautala K, Aaltonen K, Utriainen M, Kareinen L, Gadd T, Sironen T, Vapalahti O, Kinnunen PM. Antibody responses to equine parapoxvirus reveal a re-emerging pattern. BMC Vet Res 2026 Jan 24;22(1):111.
                        doi: 10.1186/s12917-026-05314-0pubmed: 41580677google scholar: lookup
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