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Journal of the South African Veterinary Association2010; 80(4); 233-236; doi: 10.4102/jsava.v80i4.214

Partial intravenous anaesthesia in 5 horses using ketamine, lidocaine, medetomidine and halothane.

Abstract: A partial intravenous protocol was used successfully to maintain anaesthesia in 5 healthy horses. Horses were premedicated with acepromazine, romifidine and butorphanol, induced with guaifenesin and ketamine and maintained on a constant rate infusion of lidocaine, ketamine and medetomidine together with halothane inhalation anaesthesia. Mean end-tidal halothane concentration to maintain a surgical plane of anaesthesia was 0.8 +/- 0.2%. Mean dobutamine requirement to maintain mean arterial pressure above 9.31 kPa was 0.42 +/- 0.3 microg/kg/min. The administration of relatively low doses of lidocaine, ketamine and medetomidine together with halothane resulted in haemodynamically stable anaesthesia, followed by smooth recovery.
Publication Date: 2010-05-13 PubMed ID: 20458864DOI: 10.4102/jsava.v80i4.214Google Scholar: Lookup
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  • Journal Article

Summary

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This study outlines a new protocol for anaesthesia in horses that combines intravenous and inhalation methods, and reports its successful use in five horses.

Introduction

  • This research centers on anaesthesia in veterinary practices, more specifically, in horses.
  • The objective was to explore a mixed protocol for inducing and maintaining anaesthesia in horses using a combination of intravenous (IV) and inhalation methods. This protocol incorporated various drugs including Ketamine, lidocaine, Medetomidine and halothane.

Methodology

  • Five healthy horses were used for this experiment.
  • Before anaesthesia, horses were premedicated with a cocktail of drugs: acepromazine, romifidine, and butorphanol. This premedication process is meant to prepare the body for anaesthesia, ensuring that the procedure is safe and effective.
  • Anaesthesia induction was then conducted using a combination of guaifenesin and ketamine.
  • Afterwards, the anaesthesia was sustained with a constant rate infusion of lidocaine, ketamine, and medetomidine, together with inhalation of halothane.

Results and Observations

  • The mean end-tidal halothane concentration required to maintain a surgical plane of anaesthesia turned out to be 0.8 +/- 0.2%.
  • In terms of maintaining mean arterial pressure, the mean dobutamine requirement was about 0.42 +/- 0.3 micrograms per kilogram per minute.
  • The combination of relatively low doses of lidocaine, ketamine, and medetomidine alongside halothane managed to provide haemodynamically stable anaesthesia.

Conclusion

  • The end result of the experimental protocol was successful with all horses experiencing smooth recovery following the anaesthesia.
  • The study concludes that the combined use of intravenous drugs with inhalation anaesthesia is effective in inducing and sustaining anaesthesia in horses, while also ensuring stable physiological conditions and good recovery.

Cite This Article

APA
Kruger K, Stegmann GF. (2010). Partial intravenous anaesthesia in 5 horses using ketamine, lidocaine, medetomidine and halothane. J S Afr Vet Assoc, 80(4), 233-236. https://doi.org/10.4102/jsava.v80i4.214

Publication

ISSN: 1019-9128
NlmUniqueID: 7503122
Country: South Africa
Language: English
Volume: 80
Issue: 4
Pages: 233-236

Researcher Affiliations

Kruger, K
  • Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110 South Africa.
Stegmann, G F

    MeSH Terms

    • Acepromazine / administration & dosage
    • Anesthesia Recovery Period
    • Anesthesia, Intravenous / veterinary
    • Anesthetics / administration & dosage
    • Anesthetics, Combined / administration & dosage
    • Animals
    • Butorphanol / administration & dosage
    • Dose-Response Relationship, Drug
    • Female
    • Guaifenesin / administration & dosage
    • Halothane / administration & dosage
    • Hemodynamics / drug effects
    • Hemodynamics / physiology
    • Horse Diseases / chemically induced
    • Horse Diseases / prevention & control
    • Horse Diseases / surgery
    • Horses / physiology
    • Hypotension / chemically induced
    • Hypotension / prevention & control
    • Hypotension / veterinary
    • Imidazoles / administration & dosage
    • Infusions, Intravenous / veterinary
    • Ketamine / administration & dosage
    • Lidocaine / administration & dosage
    • Male
    • Medetomidine / administration & dosage

    Citations

    This article has been cited 2 times.
    1. Gozalo-Marcilla M, Ringer SK. Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature. Animals (Basel) 2021 Jun 14;11(6).
      doi: 10.3390/ani11061777pubmed: 34198637google scholar: lookup
    2. Dupont J, Serteyn D, Sandersen C. Prolonged Recovery From General Anesthesia Possibly Related to Persistent Hypoxemia in a Draft Horse. Front Vet Sci 2018;5:235.
      doi: 10.3389/fvets.2018.00235pubmed: 30327770google scholar: lookup