Percutaneous lung biopsy in the horse: comparison of two instruments and repeated biopsy in horses with induced acute interstitial pneumopathy.
Abstract: The aim of the study reported here was to compare complications of lung biopsy in horses and the quality of the lung specimens after biopsy using the manual Tru-Cut biopsy needle (TC) and an automated biopsy needle (ABN). For experiment 1, lung biopsy was performed in 50 horses with one instrument on one side of the thorax, and then with the other instrument on the other side. Postmortem examination was performed in 20 of the 50 horses. Coughing was detected in 10 of 50 horses and epistaxis was observed in 6 of the 50 horses. Endoscopy revealed bleeding into the airways in 16 of 49 horses and in 5 of 49 horses after biopsy with the TC or the ABN, respectively. Use of the ABN induced a significantly smaller amount of bleeding. Pneumothorax was detected by radiography in 1 of 50 horses. Hematoma diameter determined in 7 of 20 horses at postmortem examination, was significantly larger after biopsy with the TC than with the ABN. The quality of the lung specimen was good. In experiment 2, complications after repeated and multiple lung biopsies in 6 horses were evaluated. Moderate epistaxis was observed on 13 of 104 occasions. Bleeding into the airways was detected at endoscopy on 41 of 104 occasions, and pneumothorax was detected during 4 of 104 occasions. Complications such as hematoma at the biopsy site and bleeding into the airways were greater after biopsy with the TC than after use of the ABN. Lung biopsy specimens obtained with the ABN were fairly safe for the animal.
Publication Date: 2006-09-08 PubMed ID: 16955824DOI: 10.1892/0891-6640(2006)20[968:plbith]2.0.co;2Google Scholar: Lookup
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- Comparative Study
- Journal Article
Summary
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The research examined the complications and efficacy of two lung biopsy tools in horses, with results suggesting that automated biopsy needles (ABN) induced less bleeding and fewer complications than the manual Tru-Cut biopsy needle (TC).
Study Design and Methodology:
- The study was divided into 2 experiments. In the first experiment, lung biopsies were performed on 50 horses using both instruments, with one used on one side of the thorax and the other on the other side. Post-mortem examinations were carried out on 20 horses.
- In the second experiment, repeated and multiple lung biopsies were carried out on 6 horses. The aim was to evaluate the complications arising from repeated biopsy.
Findings from the First Experiment:
- Of the 50 horses that underwent biopsy, there were observations of coughing and nose bleeding in some animals. The endoscopy revealed that more horses bled into the airways after biopsy with the TC compared to the ABN.
- Only one horse had a pneumothorax, a condition where air accumulates in the chest cavity, which was detectable via radiography.
- The diameter of the hematoma, a swelling of clotted blood, was significantly larger in horses biopsied with the TC compared to those biopsied with the ABN. This was determined during post-mortem examinations of 7 out of 20 horses.
Findings from the Second Experiment:
- There were instances of nose bleeding observed on 13 out of 104 occasions. Bleeding into the airway was detected via endoscopy on 41 out of 104 occasions, while a pneumothorax condition was detected 4 times.
- Complications such as hematoma at the biopsy site and bleeding into the airways were more prevalent with the use of the TC than the ABN.
Conclusions:
- The research concluded that the ABN led to significantly less bleeding and fewer complications than the TC. It was also suggested that lung biopsy specimens obtained with the ABN were relatively safe for horses.
Cite This Article
APA
Venner M, Schmidbauer S, Drommer W, Deegen E.
(2006).
Percutaneous lung biopsy in the horse: comparison of two instruments and repeated biopsy in horses with induced acute interstitial pneumopathy.
J Vet Intern Med, 20(4), 968-973.
https://doi.org/10.1892/0891-6640(2006)20[968:plbith]2.0.co;2 Publication
Researcher Affiliations
- Equine Clinic, University of Veterinary Medicine Hannover, Foundation, Germany. monica.venner@tiho-hannover.de
MeSH Terms
- Animals
- Biopsy, Needle / instrumentation
- Biopsy, Needle / veterinary
- Female
- Horse Diseases / diagnosis
- Horses
- Lung / pathology
- Lung Diseases, Interstitial / diagnosis
- Lung Diseases, Interstitial / veterinary
- Male
Citations
This article has been cited 4 times.- Davis KU, Sheats MK. The Role of Neutrophils in the Pathophysiology of Asthma in Humans and Horses.. Inflammation 2021 Apr;44(2):450-465.
- Barton AK, Shety T, Bondzio A, Einspanier R, Gehlen H. Metalloproteinases and Their Tissue Inhibitors in Comparison between Different Chronic Pneumopathies in the Horse.. Mediators Inflamm 2015;2015:569512.
- Burgess BA, Hendrick SH, Pollock CM, Hannon SJ, Abutarbush SM, Vogstad A, Jim GK, Booker CW. The use of lung biopsy to determine early lung pathology and its association with health and production outcomes in feedlot steers.. Can J Vet Res 2013 Oct;77(4):281-7.
- Burgess BA, Hendrick SH, Pollock CM, Abutarbush SM, Vogstad A, Jim GK, Booker CW. The development of a novel percutaneous lung biopsy procedure for use on feedlot steers.. Can J Vet Res 2011 Oct;75(4):254-60.
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