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Home / Equine Research Bank / Can Vet J / Periocular sarcoid with bone invasion in a Thoroughbred mare...
The Canadian veterinary journal = La revue veterinaire canadienne2020; 61(4); 415-419;

Periocular sarcoid with bone invasion in a Thoroughbred mare.

Abstract: A periocular nodular sarcoid was diagnosed on the right upper eyelid and medial canthus of a 12-year-old Thoroughbred mare. Enucleation was performed and during the procedure the mass was noted to be firmly adhered to the underlying frontal bone. Partial ostectomy of the dorsal orbital rim was performed. Histopathology revealed invasion of the cortical lamellar bone and the bone marrow by neoplastic spindle cells and extension of these cells to multiple surgical margins. Recurrence at the level of the surgical site and its surroundings occurred 3 months after the procedure. The horse was euthanized 12 months later. Key clinical message: Invasion of the underlying bone occurs in some cases of equine periocular sarcoids. The case highlights how this bone invasion might affect the surgical planning and shows potential aggressiveness of this type of tumor. Un sarcoïde nodulaire péri-oculaire fut diagnostiqué sur la paupière supérieure droite et le canthus médial d’une jument Thoroughbred âgée de 12 ans. L’énucléation fut effectuée et durant la procédure il fut noté que la masse était fermement adhérée à l’os frontal sous-jacent. Une ostectomie partielle de la bordure orbitale dorsale fut effectuée. L’examen histopathologique révéla l’invasion de l’os lamellaire cortical et de la moelle osseuse par des cellules fusiformes néoplasiques et l’extension de ces cellules à de multiples bordures chirurgicales. Une récurrence au site chirurgical et son entourage s’est produit 3 mois après la procédure. Le cheval fut euthanasié 12 mois plus tard.Message clinique clé:Ce cas démontre que l’invasion de l’os sous-jacent se produit dans certains cas de sarcoïdes péri-oculaires équins. Ce cas souligne comment cette invasion osseuse peut affecter la planification chirurgicale et montre le potentiel agressif de ce type de tumeur.(Traduit par D Serge Messier).
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Publication Date: 2020-04-08 PubMed ID: 32255829PubMed Central: PMC7074116
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article details a case of a Thoroughbred mare with a periocular sarcoid tumor that had invaded the underlying bone. Despite surgical intervention, the horse experienced tumor recurrence and was euthanized one year later.

Case Presentation

  • The case involves a 12-year-old Thoroughbred mare who was diagnosed with a periocular nodular sarcoid on the right upper eyelid and medial canthus.
  • Due to the severe nature of the condition, enucleation was performed – a surgical procedure in which the entire eyeball is removed.
  • During the procedure, it was found that the tumor was firmly attached to the underlying frontal bone, indicating bone invasion. Consequently, part of the frontal bone (the dorsal orbital rim) was also removed, a procedure known as partial ostectomy.

Postoperative Examination and Detection of Bone Invasion

  • The removed tissue was sent for histopathological examination, a study of tissue to diagnose disease and determine the nature of abnormalities.
  • The examination revealed that the tumor had invaded the cortical lamellar bone and the bone marrow, which is unusual and concerning. Neoplastic spindle cells, which are a type of cell associated with cancer, were found to be extended to multiple surgical margins, indicating the possibility of tumor spread beyond the site of the tumor.

Tumor Recurrence and Euthanasia

  • Three months after the surgical procedure, tumor recurrence was noted at the level of the surgical site and its surroundings.
  • Given the aggressive nature of the tumor and poor outlook for the mare, the decision was made to euthanize the horse 12 months after the initial surgery.

Key Clinical Message

  • This case highlights that in some instances of equine periocular sarcoids, there can be invasion of the underlying bone. This is an important consideration for surgical planning and when assessing the aggressiveness of the tumor.
  • It also adds to the field’s understanding of the potential complexity and severity of periocular sarcoids in horses.

Cite This Article

APA
Giraldo A, Pinard CL, Plattner BL, Dubois MS. (2020). Periocular sarcoid with bone invasion in a Thoroughbred mare. Can Vet J, 61(4), 415-419.

Publication

The Canadian veterinary journal = La revue veterinaire canadienne
ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 61
Issue: 4
Pages: 415-419

Researcher Affiliations

Giraldo, Andres
  • Department of Clinical Studies (Giraldo, Pinard, Dubois), Department of Pathobiology (Plattner), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.
Pinard, Chantale L
  • Department of Clinical Studies (Giraldo, Pinard, Dubois), Department of Pathobiology (Plattner), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.
Plattner, Brandon L
  • Department of Clinical Studies (Giraldo, Pinard, Dubois), Department of Pathobiology (Plattner), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.
Dubois, Marie-Soleil
  • Department of Clinical Studies (Giraldo, Pinard, Dubois), Department of Pathobiology (Plattner), Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario N1G 2W1.

MeSH Terms

  • Animals
  • Female
  • Horse Diseases
  • Horses
  • Skin Diseases / veterinary

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Citations

This article has been cited 1 times.
  1. Sypniewska A, Ziółkowska N. Nodular conjunctivitis as a novel ocular manifestation of canine sterile granuloma/pyogranuloma syndrome. BMC Vet Res 2026 Jan 19;22(1):96.
    doi: 10.1186/s12917-026-05289-ypubmed: 41549266google scholar: lookup
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