Analyze Diet
Journal of veterinary pharmacology and therapeutics2011; 35(4); 413-416; doi: 10.1111/j.1365-2885.2011.01356.x

Pharmacokinetics of concurrently administered intravenous lidocaine and flunixin in healthy horses.

Abstract: No abstract available
Publication Date: 2011-12-02 PubMed ID: 22132770PubMed Central: PMC4219550DOI: 10.1111/j.1365-2885.2011.01356.xGoogle Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article
  • Research Support
  • N.I.H.
  • Extramural
  • Research Support
  • Non-U.S. Gov't

Cite This Article

APA
Waxman SJ, KuKanich B, Milligan M, Beard WL, Davis EG. (2011). Pharmacokinetics of concurrently administered intravenous lidocaine and flunixin in healthy horses. J Vet Pharmacol Ther, 35(4), 413-416. https://doi.org/10.1111/j.1365-2885.2011.01356.x

Publication

ISSN: 1365-2885
NlmUniqueID: 7910920
Country: England
Language: English
Volume: 35
Issue: 4
Pages: 413-416

Researcher Affiliations

Waxman, S J
  • Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.
KuKanich, B
    Milligan, M
      Beard, W L
        Davis, E G

          MeSH Terms

          • Anesthetics, Local / administration & dosage
          • Anesthetics, Local / pharmacokinetics
          • Animals
          • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
          • Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics
          • Clonixin / administration & dosage
          • Clonixin / analogs & derivatives
          • Clonixin / pharmacokinetics
          • Drug Therapy, Combination
          • Horses / blood
          • Lidocaine / administration & dosage
          • Lidocaine / pharmacokinetics

          Grant Funding

          • T35 OD010979 / NIH HHS
          • T35 RR007064 / NCRR NIH HHS
          • T35RR007064. / NCRR NIH HHS

          References

          This article includes 11 references
          1. Coakley M, Peck KE, Taylor TS, Matthews NS, Mealey KL. Pharmacokinetics of flunixin meglumine in donkeys, mules, and horses.. Am J Vet Res 1999 Nov;60(11):1441-4.
            pubmed: 10566824
          2. Dickey EJ, McKenzie HC 3rd, Brown KA, de Solis CN. Serum concentrations of lidocaine and its metabolites after prolonged infusion in healthy horses.. Equine Vet J 2008 Jun;40(4):348-52.
            pubmed: 18267881doi: 10.2746/042516408x284664google scholar: lookup
          3. Engelking LR, Blyden GT, Lofstedt J, Greenblatt DJ. Pharmacokinetics of antipyrine, acetaminophen and lidocaine in fed and fasted horses.. J Vet Pharmacol Ther 1987 Mar;10(1):73-82.
          4. Feary DJ, Mama KR, Wagner AE, Thomasy S. Influence of general anesthesia on pharmacokinetics of intravenous lidocaine infusion in horses.. Am J Vet Res 2005 Apr;66(4):574-80.
            pubmed: 15900935doi: 10.2460/ajvr.2005.66.574google scholar: lookup
          5. Malone E, Ensink J, Turner T, Wilson J, Andrews F, Keegan K, Lumsden J. Intravenous continuous infusion of lidocaine for treatment of equine ileus.. Vet Surg 2006 Jan;35(1):60-6.
          6. Meyer GA, Lin HC, Hanson RR, Hayes TL. Effects of intravenous lidocaine overdose on cardiac electrical activity and blood pressure in the horse.. Equine Vet J 2001 Sep;33(5):434-7.
            pubmed: 11558736doi: 10.2746/042516401776254871google scholar: lookup
          7. Milligan M, Beard W, Kukanich B, Sobering T, Waxman S. The effect of lidocaine on postoperative jejunal motility in normal horses.. Vet Surg 2007 Apr;36(3):214-20.
          8. Milligan M, Kukanich B, Beard W, Waxman S. The disposition of lidocaine during a 12-hour intravenous infusion to postoperative horses.. J Vet Pharmacol Ther 2006 Dec;29(6):495-9.
          9. Moore RM. Principles of Medical Management of Colic. North American Veterinary Conference; Orlando, FL. 2006.
          10. Nolen-Walston R, Paxson J, Ramey DW. Evidence-based gastrointestinal medicine in horses: it's not about your gut instincts.. Vet Clin North Am Equine Pract 2007 Aug;23(2):243-66.
            pubmed: 17616313doi: 10.1016/j.cveq.2007.03.008google scholar: lookup
          11. Pellegrini-Masini A, Poppenga RH, Sweeney RW. Disposition of flunixin meglumine injectable preparation administered orally to healthy horses.. J Vet Pharmacol Ther 2004 Jun;27(3):183-6.

          Citations

          This article has been cited 2 times.
          1. Kuroda T, Minamijima Y, Nomura M, Yamashita S, Yamada M, Nagata S, Mita H, Tamura N, Fukuda K, Kuwano A, Kusano K, Toutain PL, Sato F. Medication control of flunixin in racing horses: Possible detection times using Monte Carlo simulations.. Equine Vet J 2022 Sep;54(5):979-988.
            doi: 10.1111/evj.13532pubmed: 34719043google scholar: lookup
          2. Semerdjieva S, Abdul-Razak HH, Salim SS, Yáñez-Muñoz RJ, Chen PE, Tarabykin V, Alifragis P. Activation of EphA receptors mediates the recruitment of the adaptor protein Slap, contributing to the downregulation of N-methyl-D-aspartate receptors.. Mol Cell Biol 2013 Apr;33(7):1442-55.
            doi: 10.1128/MCB.01618-12pubmed: 23382070google scholar: lookup