Plasma adrenocorticotropin, cortisol and catecholamines response to various exercises.
Abstract: The responses of plasma adrenocorticotropin (ACTH), cortisol, noradrenaline and adrenaline in 5 Thoroughbred horses to an incremental exercise and 2 relative workload exercises, at 105 and 80% maximal oxygen consumption (VO2max), on a treadmill were examined. These hormone concentrations increased (P < 0.05) with each exercise and the maximal plasma concentrations of ACTH, cortisol were observed between 5 and 30 min after the end of the exercise, while maximal catecholamine concentrations occurred just at exhaustion time. The plasma ACTH, noradrenaline and adrenaline responses during exercise were more sensitive to the intensity of exercise than that of cortisol and showed a significant correlation with blood lactate concentrations (r = 0.605, P < 0.001 for ACTH; r = 0.718, P < 0.001 for noradrenaline; r = 0.738, P < 0.001 for adrenaline). The plasma cortisol response appeared to be connected with the duration of exercise (r = 0.71, P < 0.05). The recovery of these hormones was related to the exercise styles. These results suggest that the autonomic nervous system and the pituitary-adrenal axis of the horse are efficiently stimulated by various treadmill exercises, and these hormones may be used in the evaluation of exercise-induced stress.
Publication Date: 2000-02-05 PubMed ID: 10659320DOI: 10.1111/j.2042-3306.1999.tb05286.xGoogle Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
- Research Support
- Non-U.S. Gov't
- Adrenocorticotropic Hormone (ACTH)
- Athletic Performance
- Autonomic Nervous System
- Catecholamines
- Cortisol
- Endocrine System
- Equine Health
- Exercise Test
- Exercise-Induced Pulmonary Hemorrhage
- Hormones
- Hypothalamic Pituitary Adrenal Axis
- Lactate
- Locomotion
- Oxygen
- Performance Horses
- Physiology
- Plasma
- Stress
- Thoroughbreds
- Treadmill Exercise
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research studies the effect of varying intensity exercise on hormone levels, namely ACTH, cortisol, noradrenaline, and adrenaline, in Thoroughbred horses. The findings suggest these hormones can be used to evaluate exercise-induced stress, showing changes in response to workload and highlighting the efficient stimulation of the horse’s autonomic nervous system and pituitary-adrenal axis by treadmill exercises.
Exercise Intensity and Hormone Response
- The study examines how different intensities of exercise impact the levels of certain hormones.
- These hormones include adrenocorticotropin (ACTH), cortisol, noradrenaline, and adrenaline.
- The levels of these hormones were observed in Thoroughbred horses performing treadmill exercises at varying intensities.
- The hormone concentrations were seen to increase with each exercise, with the highest levels observed between 5 and 30 minutes after the end of the exercise for ACTH and cortisol, and at exhaustion time for catecholamines.
Hormone Sensitivity and Exercise Intensity
- The study found that the responses of ACTH, noradrenaline, and adrenaline during exercise were more sensitive to exercise intensity than cortisol.
- These hormones showed a significant correlation with blood lactate concentrations, which increase along with exercise intensity – a measurement of overall athletic performance and fatigue.
- Meanwhile, the cortisol response was found to be linked with the duration of exercise, indicating cortisol might be more responsive to longer bouts of exercise.
Evaluation of Exercise-induced Stress
- The results of this study suggest that these hormones can be used as indicators of exercise-induced stress in horses.
- Varying the intensity and duration of exercised influenced levels of these hormones, indicating the activation of the pituitary-adrenal axis and the autonomic nervous system.
- The different responses of these hormones to varying exercises suggest that they could be important indicators of physiological responses and exercise-induced stress in horses.
- Understanding these hormone responses could provide valuable insights for training schedules and athletic performance monitoring.
Cite This Article
APA
Nagata S, Takeda F, Kurosawa M, Mima K, Hiraga A, Kai M, Taya K.
(2000).
Plasma adrenocorticotropin, cortisol and catecholamines response to various exercises.
Equine Vet J Suppl(30), 570-574.
https://doi.org/10.1111/j.2042-3306.1999.tb05286.x Publication
Researcher Affiliations
- Laboratory of Racing Chemistry, Tochigi, Japan.
MeSH Terms
- Adrenocorticotropic Hormone / blood
- Animals
- Epinephrine / blood
- Exercise Test / veterinary
- Female
- Horse Diseases / physiopathology
- Horses / blood
- Hydrocortisone / blood
- Male
- Norepinephrine / blood
- Oxygen Consumption
- Physical Conditioning, Animal
- Stress, Physiological / physiopathology
- Stress, Physiological / veterinary
- Workload
Citations
This article has been cited 10 times.- Henshall C, Randle H, Francis N, Freire R. The effect of stress and exercise on the learning performance of horses.. Sci Rep 2022 Feb 4;12(1):1918.
- Escalera-Valente F, Alonso ME, Lomillos-Pérez JM, Gaudioso-Lacasa VR, Alonso AJ, González-Montaña JR. Blood Biochemical Variables Found in Lidia Cattle after Intense Exercise.. Animals (Basel) 2021 Sep 30;11(10).
- Kitaura T, Sato F, Hada T, Ishimaru M, Kodama R, Nambo Y, Watanabe G, Taya K. Influence of exercise and emotional stresses on secretion of prolactin and growth hormone in Thoroughbred horses.. J Equine Sci 2021 Jun;32(2):49-53.
- Ferlazzo A, Cravana C, Fazio E, Medica P. The different hormonal system during exercise stress coping in horses.. Vet World 2020 May;13(5):847-859.
- Bohák Z, Harnos A, Joó K, Szenci O, Kovács L. Anticipatory response before competition in Standardbred racehorses.. PLoS One 2018;13(8):e0201691.
- Terada M, Momozawa Y, Komano M, Kusunose R, Sato F, Saito TR. Changes in the heart rate and plasma epinephrine and norepinephrine concentrations of the stallion during copulation.. Reprod Med Biol 2005 Jun;4(2):143-147.
- De Lange SS, Fuller A, Haw A, Hofmeyr M, Buss P, Miller M, Meyer LC. Tremors in white rhinoceroses (Ceratotherium simum) during etorphine-azaperone immobilisation.. J S Afr Vet Assoc 2017 Feb 24;88(0):e1-e10.
- Endo Y, Ishikawa Y, Arima D, Mae N, Iwamoto Y, Korosue K, Tsuzuki N, Hobo S. Effects of pre-shipping enrofloxacin administration on fever and blood properties in adult Thoroughbred racehorses transported a long distance.. J Vet Med Sci 2017 Mar 18;79(3):464-466.
- Rendle DI, Duz M, Beech J, Parkin T, Durham AE. Investigation of single and paired measurements of adrenocorticotropic hormone for the diagnosis of pituitary pars intermedia dysfunction in horses.. J Vet Intern Med 2015 Jan;29(1):355-61.
- Goldstein DS, Kopin IJ. Adrenomedullary, adrenocortical, and sympathoneural responses to stressors: a meta-analysis.. Endocr Regul 2008 Sep;42(4):111-9.
Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists
