Plasma progestagens in the pregnant mare in the first and last 90 days of gestation.

This research focuses on identifying the normal levels of plasma progestagens in pregnant mares during the first and last 90 days of gestation, observing changes and patterns that occur during these crucial periods.

Overview of Research

• The study observed levels of plasma progestagens, a type of steroid hormone vital for maintaining pregnancy, in 18 pregnant mares during specific periods of gestation.
• This aimed to establish the normative curve of plasma progestagens in pregnant mares, considering the first 90 days of gestation, and the last 90 days leading to birth.

Progestagen Levels in the Last 90 Days of Gestation

• The research indicates a significant rise in plasma progestagens from 25 ng/ml at 90 days pre-birth up to 60 ng/ml at just 10 days before birth.
• An unexpected drop to 58 ng/ml was noticed 5 days prior to birth.
• A dramatic decline in these hormones was noted after birth, plunging to 3 ng/ml or even less within 5 days.

Progestagen Levels in the First 90 Days of Gestation

• Different patterns were observed in the first 90 days of pregnancy. Here progestagens seemed to be echoing the luteal activity (ability of corpora lutea to produce progesterone), demonstrated by an increase in plasma levels from Day 30 to Day 60 of gestation.
• This reflects the essential role of progestagens in maintaining and supporting early stages of pregnancy in horses.

Significance of the Research

• This research may provide essential insights into mare reproduction, specifically in understanding hormonal changes throughout pregnancy gestation periods.
• Understanding these hormonal curves can offer crucial information for vets and breeders in predicting or diagnosing reproductive issues in mares.
• This could ultimately contribute to enhancing breeding management strategies and the overall health and wellbeing of pregnant horses.