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Journal of equine veterinary science2025; 155; 105711; doi: 10.1016/j.jevs.2025.105711

Policresulen is effective for the topical treatment of vaginal varices in a pregnant mare: Case report.

Abstract: Vaginal varicosities in mares are rarely reported, although considered relatively common. Clinical recognition can be challenging, especially during early pregnancy, due to the intermittent nature of the bleeding. This report aims to describe the diagnostic approach, clinical evolution, and treatment of a case of vaginal varicosity in a pregnant mare, emphasizing a practical and minimally invasive method. A 9-year-old Brazilian Sport Horse mare with intermittent vaginal hemorrhage underwent clinical evaluation, showing no abnormalities. Vaginoscopy with a rigid endoscope revealed varicose veins in the vestibule-vaginal region. Chemical cauterization was performed using a 36 % Policresulen solution. The treatment was well tolerated, inexpensive, and effective in controlling bleeding. The clinical sign resolved within a few days, with no recurrence observed. Rigid endoscopy proved to be a practical diagnostic tool for field use. Policresulen offered an efficient, low-cost, and minimally invasive therapeutic option for managing vaginal varicosities in mares.
Publication Date: 2025-10-30 PubMed ID: 41176074DOI: 10.1016/j.jevs.2025.105711Google Scholar: Lookup
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Summary

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Policresulen was successfully used as a topical treatment to manage vaginal varices in a pregnant mare, effectively stopping intermittent vaginal bleeding with a practical and minimally invasive procedure.

Introduction

  • Vaginal varicosities (enlarged veins) in mares are rarely documented but are believed to be relatively common.
  • These varices can cause intermittent vaginal bleeding, which is difficult to detect especially in early pregnancy.
  • The study focuses on diagnostic methods, clinical progress, and treatment options.

Case Presentation

  • A 9-year-old Brazilian Sport Horse mare was observed with intermittent vaginal hemorrhage.
  • Clinical evaluation initially showed no abnormalities despite the bleeding episodes.
  • To investigate further, vaginoscopy was performed using a rigid endoscope, allowing direct visualization of the vaginal and vestibule area.
  • The examination revealed the presence of varicose veins in the vestibule-vaginal region.

Diagnostic Approach

  • Rigid endoscopy is a practical diagnostic method usable in field conditions for spotting vaginal varices.
  • This tool allows for detailed visualization of the internal vaginal structures without causing significant discomfort.
  • Its use can help veterinarians identify vascular abnormalities that might otherwise be missed.

Treatment

  • Chemical cauterization was performed using a 36% solution of Policresulen.
  • Policresulen is a chemical agent known to promote selective coagulation and shedding of damaged tissue, and it is often used in human gynecology.
  • The application was topical, minimally invasive, and well tolerated by the mare.
  • The procedure was low-cost and easily performed in a field setting without the need for extensive equipment or hospitalization.

Clinical Outcome

  • Following treatment, the mare’s bleeding ceased within a few days.
  • No recurrence of vaginal hemorrhage was observed over the period of follow-up reported.
  • The positive response suggests that Policresulen is an effective therapeutic option for treating vaginal varices in mares.

Conclusions

  • Vaginal varicosities, although underreported, may be a relevant cause of intermittent vaginal bleeding in pregnant mares.
  • Rigid endoscopy provides a reliable and practical means of diagnosing these vascular anomalies in field conditions.
  • Topical application of Policresulen presents a practical, low-cost, minimally invasive, and successful treatment approach.
  • This case report adds valuable clinical insight into managing vaginal varices in equine veterinary practice, especially for pregnant mares where more invasive procedures may carry risks.

Cite This Article

APA
Miguel EL, Carneiro MFL, Griffo ALC, Baatsch Nascimento F, Dória RGS, Corrêa RR, Celeghini ECC. (2025). Policresulen is effective for the topical treatment of vaginal varices in a pregnant mare: Case report. J Equine Vet Sci, 155, 105711. https://doi.org/10.1016/j.jevs.2025.105711

Publication

ISSN: 0737-0806
NlmUniqueID: 8216840
Country: United States
Language: English
Volume: 155
Pages: 105711
PII: S0737-0806(25)00369-7

Researcher Affiliations

Miguel, Ellen Lara
  • Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil.
Carneiro, Maria Fernanda Lema
  • Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil.
Griffo, Ana Luiza Carriel
  • Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil.
Baatsch Nascimento, Fernanda
  • Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil.
Dória, Renata Gebara Sampaio
  • Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo (FZEA-USP), Pirassununga SP, Brazil.
Corrêa, Rodrigo Romero
  • Department of Surgery, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil.
Celeghini, Eneiva Carla Carvalho
  • Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, Faculty of Veterinary Medicine and Animal Science, University of São Paulo (FMVZ-USP), Pirassununga, SP, Brazil. Electronic address: celeghin@usp.br.

MeSH Terms

  • Female
  • Animals
  • Horses
  • Horse Diseases / drug therapy
  • Pregnancy
  • Varicose Veins / veterinary
  • Varicose Veins / drug therapy
  • Vagina / blood supply
  • Vaginal Diseases / veterinary
  • Vaginal Diseases / drug therapy

Conflict of Interest Statement

Declaration of competing interest No conflict of interest.

Citations

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