Practical Tips on Sample Handling for Hematology, Chemistry, and Cytology Testing for Equine Patients:: Getting More Bang for your Buck.
Abstract: Clinical pathology results are only as good as the quality of samples and accompanying information submitted to the diagnostic laboratory. The frustration of nondiagnostic or equivocal test results can often be avoided by taking the time to follow sample handling and submission guidelines. This article discusses preanalytical errors that commonly affect the accuracy of hematology, chemistry, and cytology testing, and offers practical tips for preventing these errors and maximizing diagnostic yield.
Copyright © 2019 Elsevier Inc. All rights reserved.
Publication Date: 2020-01-24 PubMed ID: 31987706DOI: 10.1016/j.cveq.2019.12.002Google Scholar: Lookup
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- Journal Article
- Review
- Analytical Methods
- Clinical Examination
- Clinical Findings
- Clinical Pathology
- Clinical Signs
- Clinical Study
- Cytology
- Diagnosis
- Diagnostic Technique
- Disease
- Disease Diagnosis
- Equine Diseases
- Equine Health
- Hematology
- Horses
- Laboratory Methods
- Sampling
- Veterinary Care
- Veterinary Medicine
- Veterinary Practice
- Veterinary Research
Summary
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The article provides crucial tips to enhance the accuracy and reliability of hematology, chemistry, and cytology tests in equine patients by improving the quality of sample handling and information submission to the diagnostic laboratory.
Importance of Sample Handling
- In the field of clinical pathology, the quality of samples used significantly influences the validity and reliability of test results. Wrong or poor handling of samples can cause inaccurate results or interpretation of findings, and thus, affect the diagnosis or treatment.
Understanding Preanalytical Errors
- The article goes ahead to shed light on common preanalytical errors affecting hematology, chemistry, and cytology testing. These are mistakes that occur before analysis, such as during sample collection, transportation, or preservation. Such errors lead to the production of false results, contributing to misdiagnosis and wrong treatment protocols.
- Understanding the nature and causes of such errors is vital for practitioners, helping them take the necessary precautions during preanalysis to increase the chances of getting accurate results.
Practical Tips to Maximize Diagnostic Yield
- The article offers practical tips to prevent these errors and substantially increase the diagnostic yield (accuracy). These involve stricter adherence to the set guidelines and protocols for sample handling and submission.
- Some of these tips may include proper sample collection mechanism, appropriate labeling, efficient storage and transport to prevent degradation, and accurate documentation of necessary details.
- Implementing these tips assures healthcare providers of more “bang for their buck,” essentially meaning they get more accurate and useful diagnostic results for the resources spent.
Cite This Article
APA
Newman AW.
(2020).
Practical Tips on Sample Handling for Hematology, Chemistry, and Cytology Testing for Equine Patients:: Getting More Bang for your Buck.
Vet Clin North Am Equine Pract, 36(1), 1-14.
https://doi.org/10.1016/j.cveq.2019.12.002 Publication
Researcher Affiliations
- Department of Population Medicine and Diagnostic Sciences, Cornell University College of Veterinary Medicine, S1-056 Schurman Hall, 602 Tower Road, Ithaca, NY 14853, USA. Electronic address: alw43@cornell.edu.
MeSH Terms
- Animals
- Biopsy, Fine-Needle / economics
- Biopsy, Fine-Needle / veterinary
- Blood Chemical Analysis / economics
- Blood Chemical Analysis / veterinary
- Cytological Techniques / economics
- Cytological Techniques / veterinary
- Hematology
- Horse Diseases / blood
- Horse Diseases / diagnosis
- Horse Diseases / pathology
- Horses / blood
- Specimen Handling
- United States
Conflict of Interest Statement
Disclosure The author has nothing to disclose.
Citations
This article has been cited 1 times.- Perez-Ecija A, Buzon-Cuevas A, Aguilera-Aguilera R, Gonzalez-De Cara CA, Mendoza FJ. Blood Storage Conditions Affect Hematological Analysis in Samples From Healthy Donkeys and Donkeys With Experimentally-Induced Endotoxemia.. Front Vet Sci 2020;7:640.
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