[Precision-controlled echocardiographic left ventricular function parameters by repeated measurement on three consecutive days in trained and untrained warmblood horses].
Abstract: Echocardiographic measurements have to be reliable and reproducible with only a low day to day variability for detecting pathological changes of left ventricular myocardial function in horses. The day dependent fluctuation margin represents an important indicator for the reproducibility of a method. To find out the day to day variability of echocardiographic parameter in healthy warmblood horses, in the present study repeated echocardiographic measurements at three consecutive days were carried out (at the same time and by the same examiner) at 11 untrained and 7 trained warmblood horses. The horses were examined from the right hemithorax, in five different B- and M-Mode views in the long and short heart axis. The echocardiographic measurements in the three-day examination interval showed with coefficient of variation between 3.4 and 25.8% a good reproducibility. In order to calculate the precision of echocardiographic parameters (reproducibility from day to day) statistical analysis was carried out by means of a linear model with random effects. Herefor the variation between repeated measurements over three days and within the horses (day to day intraindividual variation) as well as the variation between the horses (interindividual variation) were taken into account. In dependency of the echocardiographic parameters 46.2-95.7% (median 85.7%) of the variation is caused by the difference between the horses (intraclass correlation) and 4.3-53.8% (median 14.3%) of the variation is caused by the repeated measurements on different days. With a coefficient of variance from 6.6% and an intraclass correlation of 0.957 the left ventricular diastolic diameter at the level of the papillary muscles showed the lowest variation between repeated measurements on different days. The heart rate with a coefficient of variance of 10.3% and an intraclass correlation of 0.462 showed the highest variation with 53.8% between the repeated measurements on different days. The precision of single echocardiographic measurements is confirmed. All parameters were also tested for differences between trained and untrained horses. Significant differences (p<0.05) could be found in the left ventricular diameter at the level of the apex cordis and under the mitral valves as well as in the systolic left ventricular area.
Publication Date: 2005-03-25 PubMed ID: 15787314
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- English Abstract
- Journal Article
- Animal Health
- Athletic Horses
- Cardiovascular Health
- Clinical Study
- Comparative Study
- Diastole
- Echocardiography
- Equine Health
- Equine Studies
- Exercise
- Heart
- Heart Rate
- Horse Training
- Left Ventricular Function
- Physiology
- Reproducibility of Results
- Statistical Analysis
- Veterinary Medicine
- Veterinary Research
- Warmblood Horses
Summary
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The research investigated the reliability of echocardiographic measurements in detecting changes in left ventricular function in horses, assessed over three consecutive days. Comparisons were made between trained and untrained warmblood horses. It was found that the echocardiographic measurements were reproducible with a variation between 3.4 and 25.8% and there were significant differences in some parameters between trained and untrained horses.
Echocardiographic Measurements in Horses
- The study focused on analyzing echocardiographic parameters in 18 warmblood horses – 11 untrained and 7 trained. This non-invasive diagnostic tool was used to evaluate the function of the left ventricle in the horses’ hearts.
- Echocardiographic measurements were taken over a period of three days at identical times and by the same examiner. This enabled the researchers to evaluate the day-to-day variability of the measurements.
- The variation between measurements over three days and within the horses (day to day intraindividual variation), as well as the variation between different horses (interindividual variation), was considered to determine the precision of echocardiographic parameters.
Reproducibility of Echocardiographic Measurements
- The researchers found good reproducibility with the coefficient of variation ranging from 3.4 to 25.8%. This reproducibility is important in medical diagnostics to ensure that the results of repeated measurements are consistent and accurate.
- The left ventricular diastolic diameter at the level of the papillary muscles showed the lowest variation between repeated measurements on different days, indicating high precision in the measurement of this particular parameter.
- On the other hand, the heart rate demonstrated the highest variation with 53.8% between repeated measurements over different days, suggesting comparatively lower precision in this measurement.
Differences between Trained and Untrained Horses
- The study also examined differences in the echocardiographic parameters between trained and untrained horses.
- Significant differences were found in the left ventricular diameter at the level of the apex cordis and under the mitral valves, as well as in the systolic left ventricular area. These differences suggest that training level can influence specific echocardiographic measurements.
Cite This Article
APA
Gehlen H, Marnette S, Rohn K, Kreienbrock L, Stadler P.
(2005).
[Precision-controlled echocardiographic left ventricular function parameters by repeated measurement on three consecutive days in trained and untrained warmblood horses].
Dtsch Tierarztl Wochenschr, 112(2), 48-54.
Publication
Researcher Affiliations
- Klinik für Pferde, Tierärztliche Hochschule Hannover. heidrun.gehlen@tiho-hannover.de
MeSH Terms
- Animals
- Echocardiography / methods
- Echocardiography / standards
- Echocardiography / veterinary
- Female
- Heart / physiology
- Horses / physiology
- Male
- Physical Conditioning, Animal / physiology
- Reference Values
- Reproducibility of Results
Citations
This article has been cited 1 times.- Gehlen H, Shety T, El-Zahar H, Hofheinz I. Measurement of plasma endothelin-1 concentration in healthy horses and horses with cardiac disease during rest and after exercise. J Vet Med Sci 2019 Feb 28;81(2):263-268.
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