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Predictors of arterial oxygen tension in anesthetized horses: 1,610 cases (1992-1994).

Abstract: To identify factors associated with various arterial partial pressures of oxygen (Pao2) in anesthetized horses. Methods: Retrospective study. Methods: 1,450 horses anesthetized a total of 1,610 times with isoflurane or halothane. Methods: Anesthesia records, particularly results of blood gas analyses, were reviewed, and horses were grouped on the basis of lowest Pao2. Results: For horses with lowest Pao2 < 120 mm Hg, those with low pulse pressure, that underwent anesthesia on an emergency basis, or that were males were more likely to have Pao2 < 80 mm Hg. For horses with lowest Pao2 < 250 mm Hg, those that were positioned in dorsal recumbency, that underwent anesthesia on an emergency basis, or that had a shorter duration of anesthesia were more likely to have lowest Pao2 < 120 mm Hg. For horses with lowest Pao2 < 400 mm Hg, those that were positioned in dorsal recumbency, that underwent anesthesia on an emergency basis, that had a shorter duration of anesthesia, that were older, that were heavier, or that were being ventilated mechanically were more likely to have lowest Pao2 < 250 mm Hg. Conclusions: Low pulse pressure, emergency case status, dorsal recumbency, and short duration of anesthesia were significantly related with lower Pao2 in anesthetized horses.
Publication Date: 1999-10-08 PubMed ID: 10511864
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  • Journal Article

Summary

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The research article focuses on the identification of factors associated with variations in partial pressures of arterial oxygen (Pao2) in horses during anesthesia. The study found that factors like low pulse pressure, emergency situations, dorsal recumbency and short duration of anesthesia significantly impacted the arterial oxygen tension.

Methods

In the study, data from 1,450 horses that underwent anesthesia 1,610 times with either isoflurane or halothane was used. The research mainly concentrated on the following:

  • Analyzing anesthesia records, specifically the outcomes of blood gas analyses.
  • Grouping horses based on the lowest recorded Pao2 during anesthesia.

Key Findings

Different categories of horses were found to be more likely to have varying degrees of Pao2 levels:

  • For horses with a lowest Pao2 of less than 120 mm Hg, factors such as low pulse pressure, anaesthesia conducted on an emergency basis, and the horse being male were associated with a Pao2 level less than 80 mm Hg.
  • In cases where the lowest Pao2 was less than 250 mm Hg, horses positioned in dorsal recumbency, those that underwent anesthesia on an urgent basis or those who had shorter durations of anesthesia were more likely to have a Pao2 of less than 120 mm Hg.
  • For horses with a lowest Pao2 of less than 400 mm Hg, factors such as being positioned in dorsal recumbency, undergoing anesthesia on an emergency basis, having shorter periods of anesthesia, being older or heavier, or being subjected to mechanical ventilation were identified as being more likely to result in a Pao2 of less than 250 mm Hg.

Conclusion

From the study, it was concluded that low pulse pressure, emergency case status, dorsal recumbency, and short duration of anesthesia have significant relationships with lower Pao2 in anesthetized horses. Therefore, consideration of these factors is necessary during the anesthesia of horses to manage their arterial oxygen tension effectively.

Cite This Article

APA
Whitehair KJ, Willits NH. (1999). Predictors of arterial oxygen tension in anesthetized horses: 1,610 cases (1992-1994). J Am Vet Med Assoc, 215(7), 978-981.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 215
Issue: 7
Pages: 978-981

Researcher Affiliations

Whitehair, K J
  • Veterinary Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA.
Willits, N H

    MeSH Terms

    • Anesthesia, Inhalation / veterinary
    • Anesthetics, Inhalation
    • Animals
    • Blood Gas Analysis / veterinary
    • Female
    • Halothane
    • Horses / blood
    • Isoflurane
    • Male
    • Oxygen / blood
    • Retrospective Studies

    Citations

    This article has been cited 4 times.
    1. Seddighi R, Doherty TJ. Anesthesia of the geriatric equine. Vet Med (Auckl) 2012;3:53-64.
      doi: 10.2147/VMRR.S34162pubmed: 30101084google scholar: lookup
    2. Karrasch NM, Hubbell JA, Aarnes TK, Bednarski RM, Lerche P. Comparison of cardiorespiratory variables in dorsally recumbent horses anesthetized with guaifenesin-ketamine-xylazine spontaneously breathing 50% or maximal oxygen concentrations. Can Vet J 2015 Apr;56(4):387-92.
      pubmed: 25829559
    3. Casoni D, Spadavecchia C, Adami C. Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases. Acta Vet Scand 2014 Aug 14;56(1):49.
      doi: 10.1186/s13028-014-0049-zpubmed: 25124268google scholar: lookup
    4. Hubbell JA, Aarnes TK, Bednarski RM, Lerche P, Muir WW. Effect of 50% and maximal inspired oxygen concentrations on respiratory variables in isoflurane-anesthetized horses. BMC Vet Res 2011 Jun 3;7:23.
      doi: 10.1186/1746-6148-7-23pubmed: 21639886google scholar: lookup