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The Journal of parasitology1999; 85(5); 968-969;

Prevalence of antibodies to Neospora caninum in horses in North America.

Abstract: Serum samples from 296 horses slaughtered for food in the United States were tested for antibodies to Neospora caninum by the Neospora-agglutination test (NAT). Antibodies were found in 69 (23.3%) horses with titers of 1:40 (19 horses), 1:80 (19 horses), 1:100 (3 horses), 1:200 (7 horses), 1:400 (4 horses), and 1:800 (17 horses). This is the first serologic survey for N. caninum antibodies in horses.
Publication Date: 1999-11-30 PubMed ID: 10577738
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  • Journal Article

Summary

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The research article reports on the first study to investigate the prevalence of Neospora caninum (a parasite causing diseases) antibodies in horses based on serum samples collected from horses slaughtered for food in the United States.

About the Research Study

  • The study aimed to determine the rate of occurrence of Neospora caninum antibodies in horses slaughtered for food consumption in the United States. This was driven by the fact that no prior research had been conducted to ascertain the presence of these antibodies among horses.
  • Neospora caninum is a parasite known to cause diseases in animals. When an animal’s body fights against this parasite, it produces antibodies. Thus, detection of these antibodies in an animal signifies that the animal’s body is or was at some point exposed to the parasite.
  • To conduct this investigation, serum samples were collected from 296 horses. The serum is the component of blood that contains antibodies, making it an appropriate sample for the test. The detection method used was the Neospora-agglutination test (NAT).

Findings of the Research

  • The researchers discovered that 23.3% of the horses (69 out of 296) tested positive for Neospora caninum antibodies.
  • The presence of antibodies was reported in different proportions, often referred to as ‘titers’. This could potentially indicate varying severity of exposure to the parasite or different stages of the disease among the horses.
  • The proportions distributed across the 69 horses, included: 19 horses with 1:40 titers, 19 with 1:80 titers, 3 with 1:100 titers, 7 with 1:200 titers, 4 with 1:400 titers, and 17 horses with 1:800 titers.
  • The data suggests a notable prevalence of Neospora caninum in horses in the U.S, warranting further investigation into the health implications and management of the parasite in horses.

Cite This Article

APA
Dubey JP, Romand S, Thulliez P, Kwok OC, Shen SK, Gamble HR. (1999). Prevalence of antibodies to Neospora caninum in horses in North America. J Parasitol, 85(5), 968-969.

Publication

ISSN: 0022-3395
NlmUniqueID: 7803124
Country: United States
Language: English
Volume: 85
Issue: 5
Pages: 968-969

Researcher Affiliations

Dubey, J P
  • US Department of Agriculture, Agricultural Research Service, Livestock and Poultry Sciences Institute, Beltsville, Maryland 20705-2350, USA.
Romand, S
    Thulliez, P
      Kwok, O C
        Shen, S K
          Gamble, H R

            MeSH Terms

            • Abattoirs
            • Agglutination Tests / veterinary
            • Animals
            • Antibodies, Protozoan / blood
            • Coccidiosis / epidemiology
            • Coccidiosis / veterinary
            • Horse Diseases / epidemiology
            • Horses
            • Neospora / immunology
            • Seroepidemiologic Studies
            • United States / epidemiology

            Citations

            This article has been cited 6 times.
            1. Talafha AQ, Abutarbush SM, Rutley DL. Seroprevalence and Potential Risk Factors Associated with Neospora spp. Infection among Asymptomatic Horses in Jordan. Korean J Parasitol 2015 Apr;53(2):163-7.
              doi: 10.3347/kjp.2015.53.2.163pubmed: 25925174google scholar: lookup
            2. Tavalla M, Sabaghan M, Abdizadeh R, Khademvatan S, Rafiei A, Razavi Piranshahi A. Seroprevalence of Toxoplasma gondii and Neospora spp. Infections in Arab Horses, Southwest of Iran. Jundishapur J Microbiol 2015 Mar;8(3):e14939.
              doi: 10.5812/jjm.14939pubmed: 25834714google scholar: lookup
            3. Hosseini M, Moraveji M, Tahamtan Y, Rahimian A, Mohammadi G, Namavari M. Seroprevalence of Neospora spp. in Horses in North East of Iran. Iran J Parasitol 2011 Jun;6(2):64-8.
              pubmed: 22347290
            4. Bártová E, Sedlák K, Syrová M, Literák I. Neospora spp. and Toxoplasma gondii antibodies in horses in the Czech Republic. Parasitol Res 2010 Sep;107(4):783-5.
              doi: 10.1007/s00436-010-1929-4pubmed: 20532561google scholar: lookup
            5. Dubey JP, Schares G, Ortega-Mora LM. Epidemiology and control of neosporosis and Neospora caninum. Clin Microbiol Rev 2007 Apr;20(2):323-67.
              doi: 10.1128/CMR.00031-06pubmed: 17428888google scholar: lookup
            6. Dubey JP. Review of Neospora caninum and neosporosis in animals. Korean J Parasitol 2003 Mar;41(1):1-16.
              doi: 10.3347/kjp.2003.41.1.1pubmed: 12666725google scholar: lookup