Analyze Diet
Journal of the American Veterinary Medical Association2019; 255(6); 710-715; doi: 10.2460/javma.255.6.710

Prevalence of exercise-induced pulmonary hemorrhage in competing endurance horses.

Abstract: To assess the prevalence of exercise-induced pulmonary hemorrhage (EIPH) among elite endurance horses after competition in a long-distance race. 20 endurance horses and 12 nonexercised or minimally exercised age-, breed-, and trainer-matched horses from the same environment (control horses). Bronchoalveolar lavage fluid samples collected from endurance horses at 3 to 8 days (sample A) and 36 to 38 days (sample B) after the race (100 km in 1 day [n = 3], 70 km/d for 2 days [12], or 100 km/d for 2 days [5]) were cytologically examined for the presence of hemosiderophages. Samples from control horses were collected at the same time as sample B was obtained from respective matched endurance horses and similarly examined. Horses with bronchoalveolar lavage fluid samples in which > 1% of identified cells were hemosiderophages were considered to have evidence of EIPH. Of 20 endurance horses, 9 (45%; 95% confidence interval, 25% to 66%) and 10 (50%; 95% confidence interval, 29% to 71%) had cytologic evidence of EIPH in samples A and B, respectively. Evidence of EIPH was present in 6 of 20 (30%) horses at both sample collection times, 3 (15%) at the first sample time only, and 4 (20%) at the second sample time only. In contrast, 1 of 12 control horses had cytologic evidence of EIPH. The prevalence of EIPH in these elite endurance horses (45% to 50%) was higher than previously reported estimates for poor-performing endurance horses; however, differences in criteria for identification of EIPH should be considered when comparing findings between studies.
Publication Date: 2019-09-04 PubMed ID: 31478814DOI: 10.2460/javma.255.6.710Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The study examines the occurrence of exercise-induced pulmonary bleeding (EIPH) in top-performing endurance horses following long-distance races. It found that the prevalence of EIPH was higher in these horses as compared to previously measured rates among less performing ones.

Introduction and Purpose of the Study

  • The study primarily aimed to understand the prevalence of Exercise-Induced Pulmonary Hemorrhage (EIPH) in elite endurance horses.
  • The researchers selected horses that competed in long-distance races.
  • The focus was to determine if high-performance physically demanding activities contribute to a high incidence of EIPH.

Methodology

  • A total of 20 endurance horses were compared with 12 non-exercised or minimally exercised horses of the same breed, age, and training conditions (control horses).
  • Researchers collected bronchoalveolar lavage fluid samples from horses at specific times after the race to assess the presence of hemosiderophages, a condition indicative of EIPH.
  • Two samples were taken: one 3 to 8 days after the race and the other 36 to 38 days after.
  • Horses with fluid samples where more than 1% of the identified cells were hemosiderophages were deemed to have EIPH.

Results

  • Out of the 20 endurance horses, 9 (45%) and 10 (50%) horses showed cytological evidence of EIPH in the first and second samples, respectively.
  • Comparatively, only one out of the twelve control horses showed signs of EIPH.
  • These results indicated a higher prevalence of EIPH in elite endurance horses, ranging from 45% to 50% after the race.

Conclusions

  • The study concluded that the incidence of EIPH was comparatively higher in high performing endurance horses than in lesser performing or unexercised endurance horses.
  • However, the findings underscore the necessity of considering variances in EIPH identification criteria when comparing results from different studies.

Cite This Article

APA
Tarancón I, Armengou L, Melendez-Lazo A, Pastor J, Ríos J, Jose-Cunilleras E. (2019). Prevalence of exercise-induced pulmonary hemorrhage in competing endurance horses. J Am Vet Med Assoc, 255(6), 710-715. https://doi.org/10.2460/javma.255.6.710

Publication

ISSN: 1943-569X
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 255
Issue: 6
Pages: 710-715

Researcher Affiliations

Tarancón, Icíar
    Armengou, Lara
      Melendez-Lazo, Antonio
        Pastor, Josep
          Ríos, José
            Jose-Cunilleras, Eduard

              MeSH Terms

              • Animals
              • Hemorrhage / veterinary
              • Horse Diseases
              • Horses
              • Lung Diseases / veterinary
              • Physical Conditioning, Animal
              • Prevalence

              Citations

              This article has been cited 3 times.
              1. Mahalingam-Dhingra A, Bedenice D, Mazan MR. Bronchoalveolar lavage hemosiderosis in lightly active or sedentary horses. J Vet Intern Med 2023 May-Jun;37(3):1243-1249.
                doi: 10.1111/jvim.16692pubmed: 36975043google scholar: lookup
              2. Rocchigiani G, Verin R, Uzal FA, Singer ER, Pregel P, Ressel L, Ricci E. Pulmonary bleeding in racehorses: A gross, histologic, and ultrastructural comparison of exercise-induced pulmonary hemorrhage and exercise-associated fatal pulmonary hemorrhage. Vet Pathol 2022 Nov;59(6):973-982.
                doi: 10.1177/03009858221117859pubmed: 35972142google scholar: lookup
              3. Shawaf T. Jugular venous thrombosis as a risk factor for exercise-induced pulmonary hemorrhage in thoroughbred racehorses. Open Vet J 2024 May;14(5):1111-1116.
                doi: 10.5455/OVJ.2024.v14.i5.4pubmed: 38938431google scholar: lookup