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Preventive veterinary medicine2016; 131; 137-145; doi: 10.1016/j.prevetmed.2016.07.011

Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK.

Abstract: The average age of the global human population is increasing, leading to increased interest in the effects of chronic disease and multimorbidity on health resources and patient welfare. It has been posited that the average age of the general veterinarian-attended horse population of the UK is also increasing, and therefore it could be assumed that chronic diseases and multimorbidity would pose an increasing risk here also. However, evidence for this trend in ageing is very limited, and the current prevalence of many chronic diseases, and of multimorbidity, is unknown. Using text mining of first-opinion electronic medical records from seven veterinary practices around the UK, Kaplan-Meier and Cox proportional hazard modelling, we were able to estimate the apparent prevalence among veterinarian-attended horses of nine chronic diseases, and to assess their relative effects on median life expectancy following diagnosis. With these methods we found evidence of increasing population age. Multimorbidity affected 1.2% of the study population, and had a significant effect upon survival times, with co-occurrence of two diseases, and three or more diseases, leading to 6.6 and 21.3 times the hazard ratio compared to no chronic disease, respectively. Laminitis was involved in 74% of cases of multimorbidity. The population of horses attended by UK veterinarians appears to be aging, and chronic diseases and their co-occurrence are common features, and as such warrant further investigation.
Publication Date: 2016-07-26 PubMed ID: 27544263DOI: 10.1016/j.prevetmed.2016.07.011Google Scholar: Lookup
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  • Journal Article

Summary

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This research investigates the prevalence and impact of chronic diseases and multimorbidity in the general veterinarian-attended horse population in the UK, revealing an increasing trend in population age and significant effects on survival times.

Study Overview

  • The increase in average age of the global human population has led to more attention being paid to chronic disease and multimorbidity, which refer to multiple health conditions occurring at once.
  • The research focuses on the potential for similar trends in the UK’s veterinarian-attended horse population. Prior to this study, there was limited evidence supporting this trend, especially in relation to the prevalence of chronic diseases and multimorbidity.

Data Collection and Analysis

  • Data was collected using text mining, a process that involves extracting high-quality information from text, of electronic medical records from seven veterinary practices across the UK.
  • By analysing this data using Kaplan-Meier estimates (used to measure the fraction of subjects living for a certain amount of time after treatment) and Cox proportional hazard modelling (used in survival analysis), the researchers could evaluate the apparent prevalence of nine chronic diseases.
  • The analysis also allowed the team to assess the relative effects of these diseases on life expectancy of horses post-diagnosis.

Findings

  • The findings provided strong evidence of an increasing population age among the general UK veterinarian-attended horse population.
  • About 1.2% of the study population showed multimorbidity – the presence of two or more chronic diseases.
  • Horses with two diseases had 6.6 times the hazard ratio (probability of death) compared to a horse with no chronic disease, while those with three or more diseases had 21.3 times the hazard ratio.
  • Laminitis, a painful and potentially crippling disease that affects the feet of a horse, was involved in 74% of multimorbidity cases.

Conclusion

  • The findings revealed that the population of horses attended by UK veterinarians appears to be aging, and that chronic diseases and their co-occurrence are common features within this population.
  • The significant impact of multimorbidity on survival times suggests that it should be a focus of further investigation in veterinary science. Chronic and co-occurring diseases pose significant risks to horse populations and require targeted treatment and management strategies.

Cite This Article

APA
Welsh CE, Duz M, Parkin TDH, Marshall JF. (2016). Prevalence, survival analysis and multimorbidity of chronic diseases in the general veterinarian-attended horse population of the UK. Prev Vet Med, 131, 137-145. https://doi.org/10.1016/j.prevetmed.2016.07.011

Publication

ISSN: 1873-1716
NlmUniqueID: 8217463
Country: Netherlands
Language: English
Volume: 131
Pages: 137-145
PII: S0167-5877(16)30213-6

Researcher Affiliations

Welsh, Claire E
  • Equine Clinical Sciences Division, Weipers Centre Equine Hospital, School of Veterinary Medicine, University of Glasgow, UK. Electronic address: Claire.Welsh@Glasgow.ac.uk.
Duz, Marco
  • School of Veterinary Medicine and Science, University of Nottingham, UK.
Parkin, Timothy D H
  • Equine Clinical Sciences Division, Weipers Centre Equine Hospital, School of Veterinary Medicine, University of Glasgow, UK.
Marshall, John F
  • Equine Clinical Sciences Division, Weipers Centre Equine Hospital, School of Veterinary Medicine, University of Glasgow, UK.

MeSH Terms

  • Animals
  • Chronic Disease
  • Comorbidity
  • Female
  • Horse Diseases / epidemiology
  • Horse Diseases / mortality
  • Horses
  • Male
  • Prevalence
  • Survival Analysis
  • United Kingdom

Citations

This article has been cited 12 times.
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