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Home / Equine Research Bank / Clin Implant Dent Relat Res / Prognosis of Deantigenated Equine Bone Used for Bone Augment...
Clinical implant dentistry and related research2013; 24(5); 591-601; doi: 10.1111/cid.12115

Prognosis of Deantigenated Equine Bone Used for Bone Augmentation: A Multicenter Retrospective Study on Early and Late Postsurgical Complications in 81 Consecutive Patients.

Abstract: To evaluate the clinical outcome of deantigenated equine bone (DEB) grafts in a series of patients treated with DEB at six months postaugmentation. Methods: One hundred DEB grafts were inserted in 81 patients between January 2004 and December 2006. Thirty-two DEBs were blocks and 68 were granules (52 sinus lift and 16 guided bone regeneration [GBR] procedures performed). A total of 147 implants were inserted. A Pearson chi-square test was used to detect any statistically significant correlation between the studied variables and early and/or late failures. Results: There were 6 early and 26 late graft failures and another 16 failures after prosthesis placement. The overall failure rate was 25% in the GBR procedures, 31.9% in sinus lift, and 54.3% with blocks, for a total complication rate of 39.5%. A statistically significant relation was detected with respect to graft type and early complications (p = .005), with a worse outcome for DEB blocks compared to granules. After provisional prosthesis restoration, 23 implants were lost, and another 41 failed after definitive prosthesis delivery, for an overall failure rate of 43.5%. The follow-up period was 3 years after surgery. Conclusions: DEB grafting material had a very high rate of complications. Blocks had more than 50% failures, mainly in the immediate postoperative period. Other procedures such as GBR and sinus lift also showed more than 25% infections and resorption, and late failures (i.e., after-implant placement) were also common. Our results show that DEB is less than ideal for crestal bone reconstruction.
© 2013 Wiley Periodicals, Inc.
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Publication Date: 2013-07-24 PubMed ID: 23879548DOI: 10.1111/cid.12115Google Scholar: Lookup
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  • Journal Article
  • Multicenter Study

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research investigates the effectiveness of using deantigenated equine bone (DEB) grafts for bone augmentation procedures in patients, and identifies a high rate of complications, both early and late, indicating that this material may not be the best choice for crestal bone reconstruction.

Study Design

  • The study was conducted retrospectively and involved 81 patients who received DEB grafts for bone augmentation procedures between January 2004 and December 2006.
  • Out of the 100 DEB grafts, 32 were blocks and 68 were granules, with 52 of them used in sinus lift procedures and 16 in guided bone regeneration (GBR) procedures.
  • A total of 147 implants were inserted, and the outcomes were monitored for a period of 3 years post-surgery.
  • The researchers used a Pearson chi-square test to detect any statistically significant correlations between the variables they studied and the occurrence of early and/or late failures.

Findings

  • The research found a high failure rate in the procedures conducted. Early failures occurred in 6 cases while late graft failures were reported in 26 cases. Another 16 failures were observed after the placement of the prosthesis.
  • The total complication rate was found to be 39.5%, with the occurrence of complications varying depending on the specific procedure and type of DEB used. GBR procedures had a failure rate of 25%, sinus lift procedures had a failure rate of 31.9%, and block DEBs had a failure rate of 54.3%.
  • The study identified a statistically significant relationship between the type of graft used and the occurrence of early complications, with block DEBs performing worse than granule DEBs.
  • Among the 147 implants inserted, 23 were lost after provisional prosthesis restoration, and an additional 41 failed after the placement of the definitive prosthesis, resulting in an overall failure rate of 43.5%.

Conclusions

  • The study concludes that DEB grafting material is associated with a high rate of complications, with over 50% failures in the case of block grafts, primarily in the immediate postoperative period.
  • Other procedures such as GBR and sinus lift also exhibited high failure rates (over 25%) due to issues like infections and resorption.
  • The study suggests that DEB is not the most suitable material for crestal bone reconstruction given the high rate of late failures, particularly after implant placement.

Cite This Article

APA
Felice P, Piana L, Jacotti M, Di Lallo S, Todisco M, Foschini MP, Checchi L, Carinci F. (2013). Prognosis of Deantigenated Equine Bone Used for Bone Augmentation: A Multicenter Retrospective Study on Early and Late Postsurgical Complications in 81 Consecutive Patients. Clin Implant Dent Relat Res, 24(5), 591-601. https://doi.org/10.1111/cid.12115

Publication

Clinical implant dentistry and related research
ISSN: 1708-8208
NlmUniqueID: 100888977
Country: United States
Language: English
Volume: 24
Issue: 5
Pages: 591-601

Researcher Affiliations

Felice, Pietro
  • Dental School - Department of Periodontology and Implantology, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Piana, Laura
  • private practice, Bologna, Bologna, Italy.
Jacotti, Michele
  • private practice, Bologna, Bologna, Italy.
Di Lallo, Sergio
  • private practice, Bologna, Bologna, Italy.
Todisco, Marzio
  • private practice, Desenzano Del Garda, Italy.
Foschini, Maria P
  • Anatomic Pathology, University of Bologna at Bellaria Hospital, Bologna, Italy.
Checchi, Luigi
  • Dental School - Department of Periodontology and Implantology, Alma Mater Studiorum - University of Bologna, Bologna, Italy.
Carinci, Francesco
  • University of Ferrara, Ferrara, Italy.

MeSH Terms

  • Alveolar Ridge Augmentation / methods
  • Animals
  • Dental Implantation, Endosseous / adverse effects
  • Dental Implantation, Endosseous / methods
  • Dental Implants / adverse effects
  • Dental Prosthesis, Implant-Supported
  • Dental Restoration Failure
  • Follow-Up Studies
  • Horses
  • Prognosis
  • Retrospective Studies
  • Treatment Outcome

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This article includes 26 references
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Citations

This article has been cited 1 times.
  1. Jamjoom A, Cohen RE. Grafts for Ridge Preservation.. J Funct Biomater 2015 Aug 7;6(3):833-48.
    doi: 10.3390/jfb6030833pubmed: 26262646google scholar: lookup
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