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Prostaglandins and reproduction in female farm animals.
Abstract: Prostaglandins impact on ovarian, uterine, placental, and pituitary function to regulate reproduction in female livestock. They play important roles in ovulation, luteal function, maternal recognition of pregnancy, implantation, maintenance of gestation, microbial-induced abortion, parturition, postpartum uterine and ovarian infections, and resumption of postpartum ovarian cyclicity. Prostaglandins have both positive and negative effects on reproduction; they are used to synchronize oestrus, terminate pseudopregnancy in mares, induce parturition, and treat retained placenta, luteinized cysts, pyometra, and chronic endometritis. Improved therapeutic uses for prostaglandins will be developed when we understand better their involvement in implantation, maintenance of luteal function, and establishment and maintenance of pregnancy.
Publication Date: 2005-01-26 PubMed ID: 16490704DOI: 10.1016/j.tvjl.2004.11.014Google Scholar: Lookup The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Journal Article
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- Non-P.H.S.
- Review
Summary
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The research article explores the critical role of prostaglandins in regulating reproductive functions such as ovulation, implantation, and gestation maintenance in female farm animals. It also discusses the positive and negative impacts of prostaglandins on reproduction, along with their therapeutic uses in conditions like chronic endometritis and pseudopregnancy.
Prostaglandins and Reproductive Functions
- The study delves into the impact of prostaglandins on various reproductive functions in female livestock, including ovarian, uterine, placental, and pituitary function. Prostaglandins are crucial in processes such as ovulation and luteal function, which are essential for reproduction.
- Prostaglandins help in the maternal recognition of pregnancy and in implantation. This means they facilitate the process where an embryo attaches and embeds itself into the uterine lining, signaling the start of pregnancy.
- The research also discusses the role of these compounds in the maintenance of gestation or pregnancy, as well as in the processes leading up to parturition, or childbirth.
The Dual Impact of Prostaglandins on Reproduction
- Prostaglandins can have both positive and negative effects on reproduction. On the positive side, they are used to synchronize oestrus, which is the reproductive cycle in some animals. This helps farmers manage and predict breeding schedules more effectively.
- Similarly, they can be used therapeutically to terminate pseudopregnancy in mares. Pseudopregnancy is a condition where the animal behaves and appears as if it’s pregnant, even when it’s not. Using prostaglandins allows the animal to end this state and return to its normal reproductive functionality.
Therapeutic Uses of Prostaglandins
- Prostaglandins are used to induce parturition, or the process of childbirth. This could be crucial in cases where the animal has difficulty delivering naturally.
- They are also utilized to treat conditions such as retained placenta, luteinized cysts, pyometra (uterine infection), and chronic endometritis (inflammation of the inner lining of the uterus).
- However, the article suggests that more understanding of the involvement of prostaglandins in various reproductive processes will help in developing improved therapeutic uses for these compounds.
Cite This Article
APA
Weems CW, Weems YS, Randel RD.
(2005).
Prostaglandins and reproduction in female farm animals.
Vet J, 171(2), 206-228.
https://doi.org/10.1016/j.tvjl.2004.11.014 Publication
Researcher Affiliations
- Department of Human Nutrition, Food, and Animal Sciences, University of Hawaii, 1955 East West Road, Honolulu, HI 96822, USA. weems@hawaii.edu
MeSH Terms
- Animals
- Animals, Domestic / physiology
- Cattle
- Embryo Implantation / physiology
- Female
- Horses
- Luteolysis / physiology
- Ovarian Follicle / physiology
- Parturition / physiology
- Pregnancy
- Prostaglandins / physiology
- Reproduction / physiology
- Sheep
- Swine
Citations
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