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Reaction to intraarterial ionic iodinated contrast medium administration in anesthetized horses.

Abstract: The purpose of this report was to evaluate the frequency and type of reactions to intraarterial iodinated contrast medium injection in horses. Ninety-seven received an intraarterial injection of ionic, iodinated contrast medium for computed tomographic assessment of the distal limb. Nine (9.0%) horses developed a reaction attributable to the contrast medium administration. Of those, 4/97 (4.0%) developed a skin response (three with urticaria, one with facial edema) within 20 min. Five (5.0%) developed elevation of heart rate and/or blood pressure immediately upon administration of the contrast medium. No horse developed a severe reaction such as shock, cardiac, or respiratory arrest. No treatment was necessary in any horse.
Publication Date: 2011-03-29 PubMed ID: 21447035DOI: 10.1111/j.1740-8261.2011.01812.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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The research paper investigates the occurrence and characteristics of reactions to iodinated contrast medium injections in horses during CT scans of the lower limb.

Objective

The primary objective of this study was to explore the frequency and types of reactions experienced by horses following the administration of an intraarterial iodinated contrast medium injection.

Methodology

  • A total of 97 horses were subjected to intraarterial iodinated contrast medium injections to enhance the visual quality of computed tomographic assessments of the distal limb.

Findings

  • Approximately 9.0% of the horses (9 out of 97) developed reactions believed to be related to the contrast medium administration.
  • Out of the horses that had reactions, 4.0% (4 out of 97) developed a skin response. These included three cases of urticaria (hives) and one case of facial swelling. These symptoms emerged within 20 minutes post-injection.
  • An additional 5.0% (5 out of 97) encountered an elevated heart rate and/or increased blood pressure immediately after receiving the contrast medium.
  • No severe reactions such as cardiac or respiratory arrest, or shock, were reported for any horse involved in the study.
  • None of the horses required any further medical treatment for their reactions.

Implications

  • The findings suggest a low incidence of reaction to iodinated contrast medium injections in horses, with no severe reactions observed.
  • It indicates the administration of iodinated contrast medium for horse-related medical imaging is relatively safe.
  • However, minor reactions like skin response and increase in heart rate and blood pressure were observed and should be acknowledged by practitioners during the administration of contrast.

Cite This Article

APA
Pollard RE, Puchalski SM. (2011). Reaction to intraarterial ionic iodinated contrast medium administration in anesthetized horses. Vet Radiol Ultrasound, 52(4), 441-443. https://doi.org/10.1111/j.1740-8261.2011.01812.x

Publication

ISSN: 1058-8183
NlmUniqueID: 9209635
Country: England
Language: English
Volume: 52
Issue: 4
Pages: 441-443

Researcher Affiliations

Pollard, Rachel E
  • Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. repollard@ucdavis.edu
Puchalski, Sarah M

    MeSH Terms

    • Anesthesia / veterinary
    • Animals
    • Contrast Media / administration & dosage
    • Contrast Media / adverse effects
    • Female
    • Forelimb / diagnostic imaging
    • Hindlimb / diagnostic imaging
    • Horse Diseases / chemically induced
    • Horses
    • Infusions, Intra-Arterial / veterinary
    • Infusions, Intravenous / veterinary
    • Iodine / adverse effects
    • Male
    • Tomography, X-Ray Computed / adverse effects
    • Tomography, X-Ray Computed / methods
    • Tomography, X-Ray Computed / veterinary

    Citations

    This article has been cited 4 times.
    1. Underberg BA, Kaessmeyer S, Schweizer D, Drews B, Van der Vekens E. Non-contrast enhanced visualization of the equine foot vasculature in a cadaver model using time-of-flight sequence. Front Vet Sci 2025;12:1585940.
      doi: 10.3389/fvets.2025.1585940pubmed: 40756806google scholar: lookup
    2. Stieger-Vanegas SM, Hanna AL. The Role of Computed Tomography in Imaging Non-neurologic Disorders of the Head in Equine Patients. Front Vet Sci 2022;9:798216.
      doi: 10.3389/fvets.2022.798216pubmed: 35321060google scholar: lookup
    3. Crijns CP, Baeumlin Y, De Rycke L, Broeckx BJ, Vlaminck L, Bergman EH, van Bree H, Gielen I. Intra-arterial versus intra venous contrast-enhanced computed tomography of the equine head. BMC Vet Res 2016 Jan 7;12:6.
      doi: 10.1186/s12917-016-0632-9pubmed: 26739315google scholar: lookup
    4. Kirberger RM, Cassel N, Carstens A, Goddard A. The effects of repeated intravenous iohexol administration on renal function in healthy beagles--a preliminary report. Acta Vet Scand 2012 Aug 14;54(1):47.
      doi: 10.1186/1751-0147-54-47pubmed: 22892108google scholar: lookup