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The Canadian veterinary journal = La revue veterinaire canadienne2022; 63(10); 1051-1056; doi: 10.1111/evj.13551

Retrospective review of atrial fibrillation in Standardbred racehorses at a tertiary care facility in Atlantic Canada.

Abstract: Atrial fibrillation (AF) is the most clinically relevant cardiac arrhythmia identified in the Standardbred racehorse. However, there is limited literature regarding athletic ability in Standardbred racehorses following AF conversion. To investigate this issue, the objectives of this review were to: i) determine the success rate in using quinidine sulphate to treat AF in a population of hospitalized equine patients in Atlantic Canada between January 2008 and December 2019; and ii) measure return to athletic ability (using racetrack earnings and top-3 finishes) following cardioversion with quinidine sulphate in a population of Standardbred racehorses. Overall, 73% (16/22) of AF instances in this study were successfully treated with enteral quinidine sulphate. No significant difference was detected in racetrack earnings or number of top-3 finishes for each horse that raced at least 5 times pre- and post-conversion. Key clinical message: To the authors' knowledge, this is the first published review to assess the athletic ability of Standardbred racehorses following cardioversion with enteral quinidine sulphate. Based on the current information, it does not appear that treatment of AF with quinidine sulphate affects future athletic performance in horses that achieved cardioversion. Examen rétrospectif de la fibrillation auriculaire chez des chevaux de course Standardbred dans un établissement de soins tertiaires au Canada Atlantique. La fibrillation auriculaire (FA) est l’arythmie cardiaque la plus cliniquement pertinente identifiée chez le cheval de course Standardbred. Cependant, il existe peu de littérature concernant la capacité athlétique des chevaux de course Standardbred après la conversion de l’FA. Pour étudier cette question, les objectifs de cette revue étaient de : i) déterminer le taux de réussite de l’utilisation du sulfate de quinidine pour traiter la FA dans une population de patients équins hospitalisés au Canada Atlantique entre janvier 2008 et décembre 2019; et ii) mesurer le retour à la capacité athlétique (en utilisant les gains en hippodrome et les trois premiers résultats) après une cardioversion avec du sulfate de quinidine dans une population de chevaux de course Standardbred. Dans l’ensemble, 73 % (16/22) des cas de FA dans cette étude ont été traités avec succès avec du sulfate de quinidine entérale. Aucune différence significative n’a été détectée dans les revenus de l’hippodrome ou le nombre de classements parmi les trois premiers pour chaque cheval ayant couru au moins cinq fois avant et après la conversion.Message clinique clé :À la connaissance des auteurs, il s’agit de la première revue publiée évaluant la capacité athlétique des chevaux de course Standardbred après une cardioversion avec sulfate de quinidine entérale. Sur la base des informations actuelles, il ne semble pas que le traitement de la FA avec du sulfate de quinidine affecte les performances sportives futures des chevaux ayant cardioversion réussie.(Traduit par Dr Serge Messier).
Publication Date: 2022-10-04 PubMed ID: 36185789PubMed Central: PMC9484198DOI: 10.1111/evj.13551Google Scholar: Lookup
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  • Journal Article
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Summary

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The research article studied how effective quinidine sulphate was in treating atrial fibrillation in Standardbred racehorses and if treatment affected their athletic ability, between 2008 and 2019. The treatment was successful in 73% of cases, and no change in athletic performance was observed post-treatment.

Objectives and Methodology

The study primarily sought to address two key research questions. The first was to evaluate the success rate of using quinidine sulphate to manage atrial fibrillation (AF) in Standardbred racehorses at a veterinary facility in Atlantic Canada. This was done by analyzing the medical records of AF equine patients from January 2008 and December 2019.

The second objective was to gauge the impact of this treatment on the racehorses’ athletic performance. To measure this, researchers looked at the horses’ racetrack earnings and top-3 finishes before and after their treatment with quinidine sulphate.

Findings

The research found that 73% of the horses responding to AF treatment were successfully treated with enteral quinidine sulphate out of all the horses analysed in the study. The study further identifies that:

  • There was no significant change in terms of racetrack earnings or the number of top-3 finishes for each horse that raced at least five times before and after the treatment.
  • Hence, it does not appear that AF treatment with quinidine sulphate negatively affects future athletic performance.

Significance

Given the limited literature addressing the athletic capability of Standardbred racehorses following AF conversion, this study is incredibly useful. The analysis was specifically focused on the use of quinidine sulphate for treatment, marking it as a first in its field.

The key takeaway from the study is that quinidine sulphate treatment for AF does not seem to impact a horse’s future athletic performance, provided successful cardioversion is achieved. This information can prove useful for equine practitioners and horse owners, enabling informed decision-making concerning the medical management of atrial fibrillation in racehorses.

Cite This Article

APA
Burns JJ, MacMillan KM, John EE. (2022). Retrospective review of atrial fibrillation in Standardbred racehorses at a tertiary care facility in Atlantic Canada. Can Vet J, 63(10), 1051-1056. https://doi.org/10.1111/evj.13551

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 63
Issue: 10
Pages: 1051-1056

Researcher Affiliations

Burns, Jennifer J
  • Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
MacMillan, Kathleen M
  • Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.
John, Emily E
  • Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, Prince Edward Island C1A 4P3.

MeSH Terms

  • Animals
  • Atrial Fibrillation / drug therapy
  • Atrial Fibrillation / veterinary
  • Canada
  • Horse Diseases / drug therapy
  • Horses
  • Quinidine / therapeutic use
  • Retrospective Studies
  • Tertiary Healthcare

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