Reversible dysphagia secondary to guttural pouch mycosis in a gelding treated medically with voriconazole and surgically with carotid occlusion and esophagostomy.
Abstract: A gelding was diagnosed with dysphagia and left guttural pouch mycosis. Treatments included topical antifungal drugs, systemic voriconazole, and balloon occlusion of the internal carotid artery. Ongoing dysphagia of neurological origin necessitated extra-oral feeding through an esophagostomy tube. Complementary case management included acupuncture. Clinical remission occurred over 10 weeks. Dysphagie réversible secondaire à une mycose de la poche gutturale chez un hongre traité médicalement avec du voriconazole et chirurgicalement par l’occlusion de la carotide et l’œsophagostomie. Un hongre a été diagnostiqué avec de la dysphagie et une mycose de la poche gutturale gauche. Les traitements ont inclus des médicaments antifongiques topiques, du voriconazole systémique et l’occlusion par ballon de l’artère carotide interne. Une dysphagie non résorbée d’origine neurologique a nécessité une alimentation extra-orale par un tube d’œsophagostomie. Une gestion du cas complémentaire a inclus l’acupuncture. Une rémission clinique s’est produite pendant 10 semaines.(Traduit par Isabelle Vallières).
Publication Date: 2018-02-02 PubMed ID: 29386677PubMed Central: PMC5764215
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
- Case Reports
- Journal Article
Summary
This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.
The research article discusses the diagnosis and treatment of a gelding, a male horse, with dysphagia and a fungal infection in the left guttural pouch. The horse was treated with antifungal medication, systemic voriconazole, balloon occlusion surgery on the artery, and by feeding through an esophagostomy tube due to persistent difficulty swallowing of neurological origin. Additionally, acupuncture was incorporated as a supplementary treatment, resulting in clinical remission over a period of ten weeks.
Diagnosis
- The subject of the research is a gelding diagnosed with dysphagia, a condition that causes difficulty in swallowing, and left guttural pouch mycosis, a fungal infection in the guttural pouch of the horse.
- The guttural pouch is a large, air-filled sac found in some species of animals including horses, which can become infected due to various microorganisms such as fungi.
Treatment Approach
- The methods used to treat the horse included the use of topical antifungal drugs and systemic voriconazole.
- Systemic voriconazole is a prescription antifungal medication that works to stop the growth of certain types of fungi.
- This indicates that the main approach to treating the horse was through medication to combat the fungal infection.
Surgery and Additional Treatment
- Additionally, the horse underwent balloon occlusion of the internal carotid artery, which is a surgical procedure that involves inserting a balloon into the artery to block or reduce blood flow. This was presumably done to prevent the spread of the fungal infection.
- Dysphagia of neurological origin, another issue affecting the horse, required the use of an esophagostomy tube for feeding. An esophagostomy is a surgically created hole that leads to the esophagus and allows for non-oral food and medication intake.
- Acupuncture, an alternative treatment therapy using needles to stimulate specific points on the body, was also integrated into the treatment plan for supplementary case management.
Outcome
- The combination of these treatments led to clinical remission of the gelding over a period of ten weeks.
- This suggests that the multifaceted treatment approach was successful in this particular case.
Cite This Article
APA
Whitehead AE, Whitty J, Scott M, Léguillette R.
(2018).
Reversible dysphagia secondary to guttural pouch mycosis in a gelding treated medically with voriconazole and surgically with carotid occlusion and esophagostomy.
Can Vet J, 59(2), 165-170.
Publication
Researcher Affiliations
- Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4 (Whitehead, Scott, Léguillette); Moore Equine Veterinary Centre, 260048A Writing Creek Crescent, Rocky View, Alberta T4A 0M9 (Whitty).
- Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4 (Whitehead, Scott, Léguillette); Moore Equine Veterinary Centre, 260048A Writing Creek Crescent, Rocky View, Alberta T4A 0M9 (Whitty).
- Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4 (Whitehead, Scott, Léguillette); Moore Equine Veterinary Centre, 260048A Writing Creek Crescent, Rocky View, Alberta T4A 0M9 (Whitty).
- Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, 2500 University Drive NW, Calgary, Alberta T2N 1N4 (Whitehead, Scott, Léguillette); Moore Equine Veterinary Centre, 260048A Writing Creek Crescent, Rocky View, Alberta T4A 0M9 (Whitty).
MeSH Terms
- Animal Structures
- Animals
- Antifungal Agents / therapeutic use
- Carotid Arteries / surgery
- Deglutition Disorders / therapy
- Deglutition Disorders / veterinary
- Esophagostomy / veterinary
- Horse Diseases / drug therapy
- Horse Diseases / surgery
- Horses
- Male
- Mycoses / drug therapy
- Mycoses / surgery
- Mycoses / veterinary
- Voriconazole / therapeutic use
References
This article includes 37 references
- Archer RM, Knight CG, Bishop WJ. Guttural pouch mycosis in six horses in New Zealand.. New Zealand Vet J 2011;60:203–209.
- Church S, Wyn-Jones G, Parks AH, Ritchie HE. Treatment of guttural pouch mycosis.. Equine Vet J 1986;18:362–365.
- Cook WR. Observations on the aetiology of epistaxis and cranial nerve paralysis in the horse.. Vet Rec 1966;78:396–406.
- Cook WR. The clinical features of guttural pouch mycosis in the horse.. Vet Rec 1968;83:336–345.
- Dobesova O, Schwarz B, Velde K, Jahn P, Zert Z, Bezdekova B. Guttural pouch mycosis in horses: A retrospective study of 28 cases.. Vet Rec 2012;171:561.
- Greet TR. Outcome of treatment in 35 cases of guttural pouch mycosis.. Equine Vet J 1987;19:483–487.
- Lepage OM, Piccot-Crézollet C. Transarterial coil embolisation in 31 horses (1999–2002) with guttural pouch mycosis: A 2-year follow-up.. Equine Vet J 2005;37:430–434.
- Brayton CF. Dimethyl sulfoxide (DMSO): A review.. Cornell Vet 1986;76:61–90.
- Freeman DE, Donawick WJ. Occlusion of internal carotid artery in the horse by means of a balloon-tipped catheter: Clinical use of a method to prevent epistaxis caused by guttural pouch mycosis.. J Am Vet Med Assoc 1980;176:236–240.
- Freeman DE, Donawick WJ. Occlusion of internal carotid artery in the horse by means of a balloon-tipped catheter: Evaluation of a method designed to prevent epistaxis caused by guttural pouch mycosis.. J Am Vet Med Assoc 1980;176:232–235.
- Freeman DE, Naylor JM. Cervical esophagostomy to permit extraoral feeding of the horse.. J Am Vet Med Assoc 1978;172:314–320.
- Colitz CM, Latimer FG, Cheng H, Chan KK, Reed SM, Pennick GJ. Pharmacokinetics of voriconazole following intravenous and oral administration and body fluid concentrations of voriconazole following repeated oral administration in horses.. Am J Vet Res 2007;68:1115–1121.
- Cook WR, Campbell RS, Dawson C. The pathology and aetiology of guttural pouch mycosis in the horse.. Vet Rec 1968;83:422–428.
- Owen RR. Epistaxis prevented by ligation of the internal carotid artery in the guttural pouch.. Equine Vet J 1974;6:143–149.
- Borges AS, Watanabe MJ. Guttural pouch diseases causing neurologic dysfunction in the horse.. Vet Clin North Am Equine Pract 2011;27:545–572.
- Eichentopf A, Snyder A, Recknagel S, Uhlig A, Waltl V, Schusser GF. Dysphagia caused by focal guttural pouch mycosis: Mononeuropathy of the pharyngeal ramus of the vagal nerve in a 20-year-old pony mare.. Irish Vet J 2013;66:13.
- Klebe EA, Holcombe SJ, Rosenstein D, Boruta D, Bartner LR, Tessier C. The effect of bilateral glossopharyngeal nerve anaesthesia on swallowing in horses.. Equine Vet J 2005;37:65–69.
- Kipar A, Frese K. Hypoglossal neuritis with associated lingual hemiplegia secondary to guttural pouch mycosis.. Vet Pathol 1993;30:574–576.
- Carmalt JL, Baptiste K. Atypical guttural pouch mycosis in three horses.. Pferdeheilkunde 2004;20:542–548.
- Virgin JE, Holcombe SJ, Caron JP. Laryngeal advancement surgery improves swallowing function in a reversible equine dysphagia model.. Equine Vet J 2016;48:362–367.
- Ludwig A, Gatineau S, Reynaud MC, Cadore JL, Bourdoiseau G. Fungal isolation and identification in 21 cases of guttural pouch mycosis in horses (1998–2002). Vet J 2005;169:457–461.
- Kendall A, Bröjer J, Karlstam E, Pringle J. Enilconazole treatment of horses with superficial Aspergillus spp. rhinitis.. J Vet Intern Med 2008;22:1239–1242.
- Davis EW, Legendre AM. Successful treatment of guttural pouch mycosis with itraconazole and topical enilconazole in a horse.. J Vet Intern Med 1994;8:304–305.
- Davis JL, Salmon JH, Papich MG. Pharmacokinetics of voriconazole after oral and intravenous administration to horses.. Am J Vet Res 2006;67:1070–1075.
- Ernst NS, Freeman DE, Mackay RJ. Progression of mycosis of the auditory tube diverticulum (guttural pouch) after arterial occlusion in a horse with contralateral temporohyoid osteoarthropathy.. J Am Vet Med Assoc 2006;229:1945–1948.
- Caron JP, Fretz PB, Bailey JV, Barber SM, Hurtig MB. Balloon-tipped catheter arterial occlusion for prevention of hemorrhage caused by guttural pouch mycosis: 13 cases (1982–1985). J Am Vet Med Assoc 1987;191:345–349.
- Jennings A, Lepage O, Mair T, Sherlock C. Surgical site infection after occlusion of the internal carotid artery with a thrombectomy catheter: Five cases.. Equine Vet Educ 2017 in press.
- Kim M-S, Xie H. Use of electroacupuncture to treat laryngeal hemiplegia in horses.. Vet Rec 2009;165:602–603.
- Zhang JH, Wang D, Liu M. Overview of systematic reviews and meta-analyses of acupuncture for stroke.. Neuroepid 2014;42:50–58.
- Carr EA, Holcombe SJ. Nutrition of critically ill horses.. Vet Clin North Am Equine Pract 2009;25:93–108.
- Stick JA, Derksen FJ, Scott EA. Equine cervical esophagostomy: Complications associated with duration and location of feeding tubes.. Am J Vet Res 1981;42:727–732.
- Cohen ND, Peloso JG. Risk factors for history of previous colic and for chronic, intermittent colic in a population of horses.. J Am Vet Med Assoc 1996;208:697–703.
- Magdesian KG. Nutrition for critical gastrointestinal illness: Feeding horses with diarrhea or colic.. Vet Clin North Am Equine Pract 2003;19:617–644.
- Naylor JM, Freeman DE, Kronfeld DS. Alimentation of hypophagic horses.. Compend Contin Educ Pract Vet 1984;6:S93–S99.
- Alexander F. A study of parotid salivation in the horse.. J Physiol 1966;184:646–656.
- Stick JA, Robinson NE, Krehbiel JD. Acid-base and electrolyte alterations associated with salivary loss in the pony.. Am J Vet Res 1981;42:733–737.
- Argenzio RA, Stevens CE. Cyclic changes in ionic composition of digesta in the equine intestinal tract.. American J Phys 1975;228:1224–1230.
Citations
This article has been cited 0 times.Use Nutrition Calculator
Check if your horse's diet meets their nutrition requirements with our easy-to-use tool Check your horse's diet with our easy-to-use tool
Talk to a Nutritionist
Discuss your horse's feeding plan with our experts over a free phone consultation Discuss your horse's diet over a phone consultation
Submit Diet Evaluation
Get a customized feeding plan for your horse formulated by our equine nutritionists Get a custom feeding plan formulated by our nutritionists