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Equine veterinary journal1994; 26(5); 348-352; doi: 10.1111/j.2042-3306.1994.tb04401.x

Review of 40 cases of lung abscesses in foals and adult horses.

Abstract: A retrospective study of 40 horses with primary lung abscesses without pleuropneumonia showed that lung abscesses occurred predominantly in young horses, usually in foals aged < or = 6 months. Hyperfibrinogenaemia was present in all but 2 horses, and other common clinical and haematological findings were hyperthermia, tachycardia, polypnoea, and neutrophilic leucocytosis. The most common bacterial species isolated from transtracheal aspirates were Streptococcus zooepidemicus (20/34) and Rhodococcus equi (13/34). Most horses (23/27) discharged from the hospital were long term survivors. Of the 19 horses for which a follow up was available, 12 raced or performed the task for which they were intended. None of the indicators evaluated in this study could reliably predict the bacterial species involved or the outcome.
Publication Date: 1994-09-01 PubMed ID: 7988535DOI: 10.1111/j.2042-3306.1994.tb04401.xGoogle Scholar: Lookup
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  • Journal Article

Summary

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This study looks retrospectively at 40 cases of lung abscesses in horses, investigating the common clinical and haematological features as well as the outcome. Results show that these abscesses tend to occur in young horses, with the most common bacterial species found to be Streptococcus zooepidemicus and Rhodococcus equi. However, none of the investigated indicators could reliably predict the bacterial species involved or the outcome of the horse’s health.

Study Background and Methodology

  • The research is a retrospective study involving 40 cases of primary lung abscesses in horses, excluding those with pleuropneumonia. The goal was to identify common clinical features and indicators, and possible outcome predictors.
  • The key factors examined included age of the horses, presence of hyperfibrinogenemia (an elevated level of fibrinogen in the blood, typically indicating inflammation), hyperthermia, tachycardia (rapid heart rate), polypnoea (rapid breathing), and neutrophilic leucocytosis (increase in the number of neutrophil white blood cells).
  • Researchers also studied the bacterial species present in the lung abscesses by collecting and analyzing transtracheal aspirates, a procedure that collects fluid and cells from the respiratory tract.

Study Findings

  • The study found that lung abscesses predominantly occurred in young horses, especially in foals aged six months or less. This may suggest these horses’ immune systems aren’t fully developed, making them more prone to infection.
  • All but two horses had hyperfibrinogenaemia, a marker of inflammation. Furthermore, other common clinical signs were hyperthermia, tachycardia, polypnoea, and neutrophilic leucocytosis. These indicators usually point to systemic inflammation and infection.
  • The most commonly isolated bacterial species from the aspirates were Streptococcus zooepidemicus and Rhodococcus equi, which are both known pathogens in horses.
  • The study also attempted to determine links between certain indicators and the type of bacterial infection and the horse’s prognosis. However, no reliable predictors were identified.

Outcomes and Aftercare

  • Despite the severity of lung abscesses, a majority of the horses (23 out of 27) that were discharged from the hospital survived long term, indicating effective treatment strategies.
  • Of the horses for which follow-up information was available, 12 were able to race or perform their intended tasks. This result suggests that even after such a serious health issue, horses can potentially return to their regular levels of activity.

Cite This Article

APA
Lavoie JP, Fiset L, Laverty S. (1994). Review of 40 cases of lung abscesses in foals and adult horses. Equine Vet J, 26(5), 348-352. https://doi.org/10.1111/j.2042-3306.1994.tb04401.x

Publication

ISSN: 0425-1644
NlmUniqueID: 0173320
Country: United States
Language: English
Volume: 26
Issue: 5
Pages: 348-352

Researcher Affiliations

Lavoie, J P
  • Département de Médecine, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada.
Fiset, L
    Laverty, S

      MeSH Terms

      • Actinomycetales Infections / diagnosis
      • Actinomycetales Infections / epidemiology
      • Actinomycetales Infections / microbiology
      • Actinomycetales Infections / veterinary
      • Age Factors
      • Animals
      • Breeding
      • Follow-Up Studies
      • Horse Diseases / diagnosis
      • Horse Diseases / epidemiology
      • Horse Diseases / microbiology
      • Horses
      • Lung Abscess / diagnosis
      • Lung Abscess / epidemiology
      • Lung Abscess / microbiology
      • Lung Abscess / veterinary
      • Prognosis
      • Quebec / epidemiology
      • Retrospective Studies
      • Rhodococcus equi / isolation & purification
      • Treatment Outcome

      Citations

      This article has been cited 7 times.
      1. Garner C, Stephen C, Pant SD, Ghorashi SA. Comparison of PCR-HRM, colorimetric LAMP and culture based diagnostic assays in the detection of endometritis caused by Streptococcus equi subsp. zooepidemicus in mares.. Vet Res Commun 2023 Jun;47(2):495-509.
        doi: 10.1007/s11259-022-10047-0pubmed: 36538151google scholar: lookup
      2. Kinoshita Y, Niwa H, Katayama Y. Development of a loop-mediated isothermal amplification method for detecting Streptococcus equi subsp. zooepidemicus and analysis of its use with three simple methods of extracting DNA from equine respiratory tract specimens.. J Vet Med Sci 2014 Sep;76(9):1271-5.
        doi: 10.1292/jvms.14-0140pubmed: 24871644google scholar: lookup
      3. de Carvalho CC, Costa SS, Fernandes P, Couto I, Viveiros M. Membrane transport systems and the biodegradation potential and pathogenicity of genus Rhodococcus.. Front Physiol 2014;5:133.
        doi: 10.3389/fphys.2014.00133pubmed: 24772091google scholar: lookup
      4. Schlusselhuber M, Jung S, Bruhn O, Goux D, Leippe M, Leclercq R, Laugier C, Grötzinger J, Cauchard J. In vitro potential of equine DEFA1 and eCATH1 as alternative antimicrobial drugs in rhodococcosis treatment.. Antimicrob Agents Chemother 2012 Apr;56(4):1749-55.
        doi: 10.1128/AAC.05797-11pubmed: 22232283google scholar: lookup
      5. Clark C, Greenwood S, Boison JO, Chirino-Trejo M, Dowling PM. Bacterial isolates from equine infections in western Canada (1998-2003).. Can Vet J 2008 Feb;49(2):153-60.
        pubmed: 18309745
      6. Sellon DC, Besser TE, Vivrette SL, McConnico RS. Comparison of nucleic acid amplification, serology, and microbiologic culture for diagnosis of Rhodococcus equi pneumonia in foals.. J Clin Microbiol 2001 Apr;39(4):1289-93.
      7. Nay TS. Extra-pulmonary Rhodococcus equi in a thoroughbred foal.. Can Vet J 1996 Oct;37(10):623-4.
        pubmed: 8896881