Reviewe: Genetics and genomics in equine exercise physiology: an overview of the new applications of molecular biology as positive and negative markers of performance and health.
Abstract: Equine breeding selection has been developed by applying quantitative genetic methods for calculating the heritability of the complex traits such as performance in racing or sport competitions. With the great development of biotechnologies, equine molecular genetics has come of age. The recent sequencing of the equine genome by an international consortium was a major advance that will impact equine genomics in the near future. With the rapid progress in equine genetics, new applications in early performance evaluation and the detection of disease markers become available. Many new biomolecular tools will change management of horse selection, disease diagnosis and treatment. The purpose of this review is to present new developments in equine genetics and genomics for performance evaluation and health markers after a short summary of the previous knowledge about the genetic components of the exercise performance traits.
© 2010 EVJ Ltd.
Publication Date: 2011-05-27 PubMed ID: 21059061DOI: 10.1111/j.2042-3306.2010.00299.xGoogle Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
- Review
Summary
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The research article presents an overview of how molecular biology has been incorporated into equine exercise physiology to predict performance and health markers. With new advancements in genetics, this field will greatly impact horse selection, disease diagnosis, and treatment methods.
Context and Background
- The article notes the significance of genetics in equine selection for racing and sporting competitions, historically assessed through quantitative genetic methods that compute the heritability of complex traits.
- With the advancements in biotechnology, equine molecular genetics has taken major leaps. The completion of the sequencing of the equine genome by an international consortium is cited as a crucial development that will significantly impact equine genomics.
Applications and Impact of Genetic Progress
- The authors discuss the potentials that have opened up with the progress in equine genetics, such as the new applications in early performance evaluation and the detection of disease markers. These developments vastly change the landscape of horse selection, disease diagnosis, and treatment.
- As genetics have a significant role in equine performance for racing or sport competitions, these new molecular biology applications become essential tools in breeding selection, aiding in predicting and enhancing racing and sporting performance.
New Developments in Equine Genetics and Genomics
- Rapid growth in equine genetics and genomics has led to the creation of biomolecular tools essential for performance evaluation and identifying health markers.
- The authors provide an account of new developments in equine genetics and genomics following a brief summary of previous knowledge about the genetic components tied to exercise performance traits.
- The review essentially aims at depicting the advancements within this field and their applications in equine exercise physiology, performance assessment, and health markers, offering a comprehensive view of the critical role of genetics and genomics in equine exercise physiology.
Cite This Article
APA
Barrey E.
(2011).
Reviewe: Genetics and genomics in equine exercise physiology: an overview of the new applications of molecular biology as positive and negative markers of performance and health.
Equine Vet J Suppl(38), 561-568.
https://doi.org/10.1111/j.2042-3306.2010.00299.x Publication
Researcher Affiliations
- Unité de Biologie Intégrative des Adaptations à l'Exercice, France. eric.barrey@inserm.fr
MeSH Terms
- Animals
- Breeding
- Genetic Markers / physiology
- Genomics
- Horses / genetics
- Horses / physiology
- Physical Conditioning, Animal / physiology
Citations
This article has been cited 4 times.- Ropka-Molik K, Stefaniuk-Szmukier M, Szmatoła T, Piórkowska K, Bugno-Poniewierska M. The use of the SLC16A1 gene as a potential marker to predict race performance in Arabian horses.. BMC Genet 2019 Sep 11;20(1):73.
- Ropka-Molik K, Stefaniuk-Szmukier M, Piórkowska K, Szmatoła T, Bugno-Poniewierska M. Molecular characterization of the apoptosis-related SH3RF1 and SH3RF2 genes and their association with exercise performance in Arabian horses.. BMC Vet Res 2018 Aug 14;14(1):237.
- Kim HA, Kim MC, Kim NY, Ryu DY, Lee HS, Kim Y. Integrated analysis of microRNA and mRNA expressions in peripheral blood leukocytes of Warmblood horses before and after exercise.. J Vet Sci 2018 Jan 31;19(1):99-106.
- Ricard A, Robert C, Blouin C, Baste F, Torquet G, Morgenthaler C, Rivière J, Mach N, Mata X, Schibler L, Barrey E. Endurance Exercise Ability in the Horse: A Trait with Complex Polygenic Determinism.. Front Genet 2017;8:89.
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