[Ryegrass cramps in horses].

This research discusses the diagnosis of rye-grass intoxication in a stallion showing signs of a neurotoxic syndrome such as lack of coordination and balance, which is attributed to the presence of a mycotoxin lolitrem B in the hay fed to the horse.

Research Objective and Methodology

• The researchers aimed to diagnose the cause of a neurotoxic syndrome that was characterized by ataxia (loss of muscle control) and incoordination in a stallion. The suspected cause was rye-grass intoxication.
• To determine the cause of this syndrome, they conducted a series of diagnostic tests, which included haematology and blood chemistry tests. These specific tests were chosen as they would reveal any organ-specific or systemic lesions that could potentially be causing the symptoms.

Findings and Conclusion

• The blood chemistry and haematology tests did not reveal any indication of organ-specific or systemic lesions. This means that none of the horse’s organs were damaged and there was no pervasive damage in the body that could explain the symptoms.
• The researchers then conducted a chemical analysis of the hay the horse was fed and found the presence of a mycotoxin called lolitrem B. This mycotoxin was found in concentrations consistent with those described in sheep and cattle exhibiting similar symptoms. This discovery led the researchers to conclude that the horse’s symptoms were indeed due to rye-grass intoxication.
• Ultimately, the horse was determined to be suffering from the rye-grass-stagger(RGS)-syndrome, which is a condition that results from ingestion of rye-grass infected with an endophyte fungus that produces neurotoxins such as lolitrem B.

Significance of the Research

• The findings of this study are vital for equine health, especially for horses fed rye-grass hay. Knowledge of the potential for rye-grass intoxication and its symptoms can aid in early diagnosis and treatment, potentially reducing morbidity and improving outcomes for affected horses.
• This research reinforces the importance of quality control and checking for the presence of harmful toxins like lolitrem B in animal feed. Proper cultivation, storage, and handling of rye-grass can play a role in limiting the mycotoxin’s presence, thus safeguarding the health of animals.