Scopolamine in racing horses: trace identifications associated with dietary or environmental exposure.
- Journal Article
- Research Support
- Non-U.S. Gov't
- Review
Summary
The study explores the worldwide occurrence of scopolamine in performance horses, which possibly comes from dietary or environmental exposure, and its potential to affect a horse’s performance.
Scopolamine in Racing Horses
The research gives attention to the widespread detection of Scopolamine, a substance that has the potential to affect the performance of horses. The presence of Scopolamine in horses can lead to hefty penalties for those involved with the horse. The study highlights that Scopolamine, often found in small-number clusters, has been noticed in performance horses globally for up to three decades. The substance is classified under ARCI class 3 and penalty class B.
- Scopolamine is generally found in plants, primarily of the Datura species.
- The research discusses the toxicity levels of these plants for horses when there is dietary or environmental exposure.
- It also discusses the basic pharmacology of Scopolamine and its precursor.
Outcome of Inadvertent Exposure
The paper also presents a review of the traits of inadvertent environmental exposure worldwide. It argues that the presence of Scopolamine, with or without atropine, is directly related to the global distribution of Scopolamine-rich plants and the sensitivity of modern drug testing in horses.
- Interestingly, only two in thirty post-match identifications of Scopolamine in horses have been associated with atropine, iterating that the failure to find atropine isn’t necessarily an indicator of the pharmaceutical administration of Scopolamine.
Thresholds in Racing Regulations
The study’s quantitative data relating to Scopolamine identifications seems consistent with the currently mandated regulatory threshold in horse racing, such as the 75 ng/mL threshold in Louisiana, USA, and the 30 ng/mL threshold used in European racing.
- This illustrates the importance of controlling and monitoring the intake or exposure of Scopolamine in horses in order to maintain fairness and safety in horse racing.
Cite This Article
Publication
Researcher Affiliations
- 1711 Lakefield North Court, Wellington, FL 33414, USA.
- College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61802, USA.
- The Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA.
- The Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA. Electronic address: ttobin@uky.edu.
MeSH Terms
- Animals
- Datura / chemistry
- Diet
- Environmental Exposure
- Forensic Toxicology
- Guidelines as Topic
- Horses / metabolism
- Performance-Enhancing Substances / chemistry
- Performance-Enhancing Substances / metabolism
- Performance-Enhancing Substances / toxicity
- Scopolamine / chemistry
- Scopolamine / metabolism
- Scopolamine / toxicity