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Home / Equine Research Bank / Theriogenology / Seasonal thyroid and lipid profiles in Thoroughbred pregnant...
Theriogenology2016; 85(9); 1582-1589; doi: 10.1016/j.theriogenology.2016.01.017

Seasonal thyroid and lipid profiles in Thoroughbred pregnant and nonpregnant mares (Equus caballus).

Abstract: The purpose of this study was to determine which physiological seasonal thyroid and lipid panel (triglyceride, [TG], total cholesterol, [tCho], high-density lipoprotein cholesterol, [HDL Cho], LDL cholesterol, phospholipids, [PDs]) changes occur in 12 Thoroughbred pregnant and six nonpregnant mares over a period of 12 months, from April to March, by into account the lactation stage. Serum total triiodothyronine (T3) and thyroxine (T4) levels were measured using immunoenzymatic assay kits; the serum lipid panel was analyzed using the enzymatic colorimetric method. One-way ANOVA reported a significant effect of time over 12 months for T3 (F = 5.46; P < 0.001) and T4 (F = 3.98; P < 0.001), in both pregnant and nonpregnant mares, and for triglyceride (F = 2.57; P < 0.01), tCho (F = 2.32; P < 0.01), HDL Cho (F = 5.60; P < 0.0001), and PDs (F = 7.01; P < 0.0001) in pregnant mares. Two-way ANOVA repoted a significant lactating effect compared with nonlactating stage for T3 (F = 8.33; P = 0.006), T4 (F = 6.43; P = 0.003), tCho (F = 10.38; P = 0.0078), HDL Cho (F = 7.64; P = 0.020), and PDs (F = 5.07; P = 0.048). Thus, it appears that under similar environmental condition, nutrition regime, and management system, lactation stage plays a significant role in the seasonal thyroid and lipid profiles in Thoroughbred pregnant mares, with higher T3, T4, and PDs values, and lower tCho and HDL Cho in lactating than nonlactating mares. The physiological values obtained in this study may be used as additional resources to evaluate thyroid and lipid profiles in Thoroughbred pregnant and nonpregnant mares, generating a wished numbers of observation, especially when the additional breed and physiological conditions are considered.
Copyright © 2016 Elsevier Inc. All rights reserved.
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Publication Date: 2016-01-29 PubMed ID: 26920797DOI: 10.1016/j.theriogenology.2016.01.017Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research conducted a study on Thoroughbred mares, both pregnant and nonpregnant, to investigate how their thyroid and lipid levels fluctuate seasonally and are affected by lactation. The results support that lactation significantly impacts the thyroid and lipid levels in pregnant Thoroughbred mares.

Study Methodology

  • The sample size of this study consisted of 12 pregnant and 6 non-pregnant Thoroughbred mares.
  • The study period was over a course of a year, from April to March.
  • The hormone levels of total triiodothyronine (T3) and thyroxine (T4) were measured using immunoenzymatic assay kits.
  • Several lipid markers – triglyceride, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and phospholipids – were analyzed using the enzymatic colorimetric method.

Findings

  • Both pregnant and nonpregnant mares exhibited significant changes in their T3 and T4 levels over the course of the 12-month period.
  • In pregnant mares, levels of triglycerides, total cholesterol, HDL cholesterol, and phospholipids significantly changed with time.
  • Lactation had a substantial effect on the T3 and T4 hormone levels, total cholesterol, HDL cholesterol, and phospholipids in the pregnant mares.

Significance

  • The lactation stage appears to have a significant role in the seasonal thyroid and lipid profiles in pregnant Thoroughbred mares.
  • Pregnant mares in the lactating stage demonstrated higher T3, T4, and phospholipid values, but lower total cholesterol and HDL cholesterol levels compared to non-lactating mares.
  • The findings of this research can serve as valuable reference data in assessing the thyroid and lipid profiles in Thoroughbred mares, particularly when considering breed and various physiological conditions.

Cite This Article

APA
Fazio E, Medica P, Cravana C, Bruschetta G, Ferlazzo A. (2016). Seasonal thyroid and lipid profiles in Thoroughbred pregnant and nonpregnant mares (Equus caballus). Theriogenology, 85(9), 1582-1589. https://doi.org/10.1016/j.theriogenology.2016.01.017

Publication

Theriogenology
ISSN: 1879-3231
NlmUniqueID: 0421510
Country: United States
Language: English
Volume: 85
Issue: 9
Pages: 1582-1589
PII: S0093-691X(16)00030-3

Researcher Affiliations

Fazio, Esterina
  • Department of Veterinary Sciences, Unit of Veterinary Physiology, University of Messina, Messina, Italy. Electronic address: fazio@unime.it.
Medica, Pietro
  • Department of Veterinary Sciences, Unit of Veterinary Physiology, University of Messina, Messina, Italy.
Cravana, Cristina
  • Department of Veterinary Sciences, Unit of Veterinary Physiology, University of Messina, Messina, Italy.
Bruschetta, Giuseppe
  • Department of Veterinary Sciences, Unit of Veterinary Biochemistry, University of Messina, Messina, Italy.
Ferlazzo, Adriana
  • Department of Veterinary Sciences, Unit of Veterinary Physiology, University of Messina, Messina, Italy.

MeSH Terms

  • Animals
  • Female
  • Horses / metabolism
  • Lipids / blood
  • Pregnancy
  • Pregnancy, Animal / metabolism
  • Seasons
  • Thyroxine / blood
  • Triiodothyronine / blood

Citations

This article has been cited 6 times.
  1. Fazio E, Bionda A, Chiofalo V, La Fauci D, Randazzo C, Pino A, Crepaldi P, Attard G, Liotta L, Lopreiato V. Effects of Dietary Enrichment with Olive Cake on the Thyroid and Adrenocortical Responses in Growing Beef Calves.. Animals (Basel) 2023 Jun 26;13(13).
    doi: 10.3390/ani13132120pubmed: 37443918google scholar: lookup
  2. Fazio E, Bionda A, Chiofalo V, Crepaldi P, Lopreiato V, Medica P, Liotta L. Adaptive Responses of Thyroid Hormones, Insulin, and Glucose during Pregnancy and Lactation in Dairy Cows.. Animals (Basel) 2022 May 28;12(11).
    doi: 10.3390/ani12111395pubmed: 35681859google scholar: lookup
  3. Liotta L, Bionda A, Quartuccio M, De Nardo F, Visalli R, Fazio E. Thyroid and Lipidic Profiles in Nicastrese Goats (Capra hircus) during Pregnancy and Postpartum Period.. Animals (Basel) 2021 Aug 12;11(8).
    doi: 10.3390/ani11082386pubmed: 34438843google scholar: lookup
  4. Arfuso F, Giannetto C, Bazzano M, Assenza A, Piccione G. Physiological Correlation between Hypothalamic-Pituitary-Adrenal Axis, Leptin, UCP1 and Lipid Panel in Mares during Late Pregnancy and Early Postpartum Period.. Animals (Basel) 2021 Jul 9;11(7).
    doi: 10.3390/ani11072051pubmed: 34359179google scholar: lookup
  5. Rossi G, Richardson A, Jamaludin H, Secombe C. Preanalytical variables affecting the measurement of serum paraoxonase-1 activity in horses.. J Vet Diagn Invest 2021 Jan;33(1):59-66.
    doi: 10.1177/1040638720974745pubmed: 33225843google scholar: lookup
  6. Robeck TR, Amaral RS, da Silva VMF, Martin AR, Montano GA, Brown JL. Thyroid hormone concentrations associated with age, sex, reproductive status and apparent reproductive failure in the Amazon river dolphin (Inia geoffrensis).. Conserv Physiol 2019;7(1):coz041.
    doi: 10.1093/conphys/coz041pubmed: 31384468google scholar: lookup
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