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Selected pathological changes of the mare uterus and ovary.

Abstract: Focal enlargements of the uterus are palpable through the rectal wall and have various aetiology. Aspects of their diagnosis, possible pathogenesis, significance and treatment are presented. Lymphatic lacunae appear to be quite common in older mares and may occasionally give rise to large endometrial cyst, but more frequently cause widespread change throughout the uterine horns. Three unusual ovarian abnormalities are presented, a large, oestrogen-producing granulosa cell tumour, an oestrogen-producing large follicle in a 4-month-old filly, and an ectopic progesterone-producing adrenal structure bordering on neoplasia.
Publication Date: 1975-10-01 PubMed ID: 1060802
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  • Journal Article

Summary

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The research focuses on diverse pathological conditions affecting the uterus and ovary of mares, exploring their diagnosis, possible causes, significances, and remedial measures.

Uterine Pathologies

  • The study delves into different types of focal enlargements on a mare’s uterus which can be palpated through the rectal wall. A plethora of causes are discussed and the authors hypothesize that certain factors could contribute to these uterine conditions.
  • With regard to the diagnosis of these enlargements, potential pathogeneses are considered. The authors also debate their significance and possible treatment protocols, suggesting avenues for further investigations.
  • Another uterine anomaly investigated is lymphatic lacunae, often found in aging mares. While they often give rise to sizeable endometrial cysts, they usually result in widespread alteration throughout the uterine horns.

Ovarian Abnormalities

  • The authors highlight three unusual ovarian abnormalities in mares. The first abnormality is a large, estrogen-producing granulosa cell tumor.
  • The second anomaly is a large follicle producing estrogen in a four-month-old filly. This case is particularly intriguing due to the young age of the affected filly, pointing to a potentially early-onset of the condition.
  • The third ovarian condition explored is an ectopic, progesterone-producing structure located near the adrenal gland. This condition appears to be bordering on neoplasia, indicating the possibility of a malignant transformation.

Overall, this research offers comprehensive insight into specific pathological conditions affecting the reproductive organs of mares, providing valuable contributions to the existing body of veterinary pathology literature.

Cite This Article

APA
Kenney RM, Ganjam VK. (1975). Selected pathological changes of the mare uterus and ovary. J Reprod Fertil Suppl(23), 335-339.

Publication

ISSN: 0449-3087
NlmUniqueID: 0225652
Country: England
Language: English
Issue: 23
Pages: 335-339

Researcher Affiliations

Kenney, R M
    Ganjam, V K

      MeSH Terms

      • Animals
      • Cysts / pathology
      • Cysts / veterinary
      • Diagnosis, Differential
      • Endometrium / pathology
      • Female
      • Horse Diseases / pathology
      • Horses
      • Lymphatic Diseases / pathology
      • Lymphatic Diseases / veterinary
      • Myometrium / pathology
      • Ovarian Diseases / veterinary
      • Ovarian Neoplasms / pathology
      • Ovarian Neoplasms / veterinary
      • Ovary / pathology
      • Uterine Diseases / pathology
      • Uterine Diseases / veterinary
      • Uterus / pathology

      Citations

      This article has been cited 4 times.
      1. Hanada M, Maeda Y, Oikawa MA. Histopathological characteristics of endometrosis in thoroughbred mares in Japan: results from 50 necropsy cases. J Equine Sci 2014;25(2):45-52.
        doi: 10.1294/jes.25.45pubmed: 25013358google scholar: lookup
      2. Aresu L, Benali S, Giannuzzi D, Mantovani R, Castagnaro M, Falomo ME. The role of inflammation and matrix metalloproteinases in equine endometriosis. J Vet Sci 2012 Jun;13(2):171-7.
        doi: 10.4142/jvs.2012.13.2.171pubmed: 22705739google scholar: lookup
      3. Gustafsson H, Larsson K, Gustavsson I. Karyotypes and morphological and histological alterations of the genital tracts of repeat breeder heifers with known breeding history. Acta Vet Scand 1985;26(1):1-12.
        doi: 10.1186/BF03546559pubmed: 4036747google scholar: lookup
      4. MacLachlan NJ. Ovarian disorders in domestic animals. Environ Health Perspect 1987 Aug;73:27-33.
        doi: 10.1289/ehp.877327pubmed: 3665869google scholar: lookup