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Parasite (Paris, France)2017; 24; 27; doi: 10.1051/parasite/2017030

Seroepidemiology of Sarcocystis neurona and Neospora hughesi infections in domestic donkeys (Equus asinus) in Durango, Mexico.

Abstract: There is currently no information regarding Sarcocystis neurona and Neospora hughesi infections in donkeys in Mexico. Here, we determined the presence of antibodies against S. neurona and N. hughesi in donkeys in the northern Mexican state of Durango. Serum samples of 239 domestic donkeys (Equus asinus) were assayed for S. neurona and N. hughesi antibodies using home-made enzyme-linked immunoassays; six (2.5%) of the 239 donkeys tested seropositive for S. neurona. The seroprevalence of S. neurona infection was comparable among donkeys regardless of their origin, health status, or sex. Multivariate analysis showed that seropositivity to S. neurona was associated with increased age (OR = 2.95; 95% CI: 1.11-7.82; p = 0.02). Antibodies to N. hughesi were found in two (0.8%) of the 239 donkeys. Both exposed donkeys were healthy, 3- and 6-year-old females. This is the first evidence of S. neurona and N. hughesi infections in donkeys in Mexico. Il n’y a actuellement aucune information concernant les infections par et chez les ânes au Mexique. Dans cet article, nous avons déterminé la présence d’anticorps contre et chez les ânes dans l’État de Durango au nord du Mexique. Des échantillons de sérum de 239 ânes domestiques () ont été testés pour les anticorps de et à l’aide d’immunoessais enzymatiques faits maison; six (2.5 %) des 239 ânes ont été testés séropositifs pour . La séroprévalence de l’infection par était comparable chez les ânes, quels que soient leur origine, leur état de santé ou leur sexe. L’analyse multivariée a montré que la séropositivité à était associée à l’âge (OR = 2.95 ; IC à 95 % : 1.11-7.82 ;  = 0.02). Les anticorps contre ont été trouvés chez 2 (0.8 %) des 239 ânes. Les deux ânes positifs étaient des femelles de 3 à 6 ans en bonne santé. Ceci est la première preuve d’infections à et chez les ânes au Mexique.
© C. Alvarado-Esquivel et al., published by EDP Sciences, 2017.
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Publication Date: 2017-07-21 PubMed ID: 28730993PubMed Central: PMC5520387DOI: 10.1051/parasite/2017030Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the prevalence of antibodies against Sarcocystis neurona and Neospora hughesi, two parasitic infections, in domestic donkeys in the Mexican state of Durango. The study found that 2.5% of the sampled donkeys had antibodies against S. neurona and 0.8% had antibodies against N. hughesi, providing the first evidence of these infections in Mexican donkeys.

Study Details

  • The study used serum samples from 239 domestic donkeys (Equus asinus) in Durango, Mexico.
  • The researchers used home-made enzyme-linked immunoassays (ELISAs) to test for antibodies against Sarcocystis neurona and Neospora hughesi.

Findings

  • Out of the total, six donkeys (2.5%) tested positive for antibodies against S. neurona, suggesting they had been exposed to or infected with the parasite. Moreover, seropositivity was associated with a higher age, meaning older donkeys were more likely to test positive.
  • Antibodies against N. hughesi were found in two donkeys (0.8%), both of which were healthy females aged between 3 and 6 years.
  • The study found no significant differences in infection rates based on the donkeys’ sex, health status, or origin.

Significance

  • This research provides the first evidence of S. neurona and N. hughesi infections in donkeys in Mexico. These findings are essential as they fill a gap in knowledge about the presence of these diseases in this region, which can be influential for relevant disease management strategies.
  • The knowledge from this research can be used in the planning of preventive and control strategies to mitigate the spread of these infections among donkeys in the region.

Cite This Article

APA
(2017). Seroepidemiology of Sarcocystis neurona and Neospora hughesi infections in domestic donkeys (Equus asinus) in Durango, Mexico. Parasite, 24, 27. https://doi.org/10.1051/parasite/2017030

Publication

Parasite (Paris, France)
ISSN: 1776-1042
NlmUniqueID: 9437094
Country: France
Language: English
Volume: 24
Pages: 27
PII: 27

Researcher Affiliations

MeSH Terms

  • Age Distribution
  • Animals
  • Antibodies, Protozoan / blood
  • Coccidiosis / epidemiology
  • Coccidiosis / immunology
  • Coccidiosis / veterinary
  • Cross-Sectional Studies
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Equidae / parasitology
  • Female
  • Male
  • Mexico / epidemiology
  • Neospora / immunology
  • Sarcocystis / immunology
  • Sarcocystosis / epidemiology
  • Sarcocystosis / immunology
  • Sarcocystosis / veterinary
  • Seroepidemiologic Studies

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This article includes 16 references
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Citations

This article has been cited 3 times.
  1. Cong W, Nie LB, Qin SY, Wang WL, Qian AD, Meng QF. Prevalence of Neospora spp. in donkeys in China. Parasite 2018;25:16.
    doi: 10.1051/parasite/2018018pubmed: 29557777google scholar: lookup
  2. Valderrama-Martinez C, Packham A, Zheng S, Smith W, Plancarte M, Aleman M. Effect of refrigeration, room temperature, and processing time on serum immunofluorescent antibody titers for Sarcocystis neurona. J Vet Intern Med 2025 Jan-Feb;39(1):e17282.
    doi: 10.1111/jvim.17282pubmed: 39715359google scholar: lookup
  3. Alshammari A, Gattan HS, Marzok M, Selim A. Seroprevalence and risk factors for Neospora spp. infection in equine in Egypt. Sci Rep 2023 Nov 19;13(1):20242.
    doi: 10.1038/s41598-023-47601-ypubmed: 37981658google scholar: lookup
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