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Home / Equine Research Bank / Pathogens / Seroexposure to Zoonotic Anaplasma and Borrelia in Dogs and ...
Pathogens (Basel, Switzerland)2023; 12(3); 470; doi: 10.3390/pathogens12030470

Seroexposure to Zoonotic Anaplasma and Borrelia in Dogs and Horses That Are in Contact with Vulnerable People in Italy.

Abstract: Equine and canine anaplasmosis and borreliosis are major tick-borne zoonotic diseases caused by and various species of (the most important being s.l.), respectively. This study evaluated the seroexposure to and in dogs and horses used in Animal-Assisted Interventions or living in contact with children, elderly people or immunocompromised persons. A total of 150 horses and 150 dogs living in Italy were equally divided into clinically healthy animals and animals with at least one clinical sign compatible with borreliosis and/or anaplasmosis (present at clinical examination or reported in the medical history). Serum samples were tested with ELISA and immunoblot for the presence of antibodies against and s.l., and the association between seropositivity and possible risk factors was analyzed using multivariate and univariate tests. Overall, 13 dogs (8.7%) and 19 horses (12.7%) were positive for at least one of the two pathogens. In addition, 1 dog (0.7%) and 12 horses (8%) were positive for antibodies against , while 12 dogs (8.0%) and 10 horses (6.7%) had antibodies against s.l. Tick infestation in the medical history of the dogs was significantly associated with seropositivity to at least one pathogen ( = 0.027; OR 7.398). These results indicate that, in Italy, ticks infected with and/or circulate in places where horses and dogs are in contact with people at risk of developing severe diseases. Awareness should be increased, and adequate control plans need to be developed to protect human and animal health, especially where vulnerable, at-risk individuals are concerned.
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Publication Date: 2023-03-16 PubMed ID: 36986392PubMed Central: PMC10054474DOI: 10.3390/pathogens12030470Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the presence of two tick-borne diseases, anaplasmosis and borreliosis, in dogs and horses in contact with vulnerable people in Italy. The findings highlight that these animals, particularly if they have a history of tick infestation, may carry pathogens that cause these diseases, risking severe health impacts on the humans they interact with.

Objective and Methodology

  • The study aimed to evaluate the seroexposure, or contact resulting in immune response, to Anaplasma and Borrelia in dogs and horses. These animals were either in animal-assisted interventions or living with children, elderly people, or immunocompromised persons.
  • Three hundred animals, equally split between dogs and horses, were used in the study. Half of these animals were clinically healthy, while the other half showed at least one clinical sign of borreliosis and/or anaplasmosis.
  • Researchers used ELISA and immunoblot tests to look for antibodies against Anaplasma and Borrelia in serum samples from the animals. They then analyzed the association between seropositivity, or the presence of antibodies in the blood, and potential risk factors.

Findings

  • The study found that 8.7% of dogs and 12.7% of horses tested positive for at least one of the two pathogens.
  • The presence of antibodies against Anaplasma was found in 0.7% of dogs and 8% of horses. For Borrelia, 8% of dogs and 6.7% of horses showed positive antibody reactions.
  • The researchers discovered a significant association between tick infestation history in dogs and seropositivity to at least one pathogen.

Implications

  • The results indicate that ticks infected with Anaplasma and/or Borrelia are present in environments where dogs and horses are in contact with high-risk populations in Italy.
  • There is an urgent need to increase awareness of this issue to protect animal and human health. Particularly, adequate control measures need to be put into place in environments involving vulnerable individuals who could develop severe diseases if infected.

Cite This Article

APA
Traversa D, Milillo P, Maggi R, Simonato G, Di Cesare A, Pezzuto C, Grillini M, Morelli S, Colombo M, Passarelli A, Grassano A, Serio P, Losurdo M, Brueckmann R. (2023). Seroexposure to Zoonotic Anaplasma and Borrelia in Dogs and Horses That Are in Contact with Vulnerable People in Italy. Pathogens, 12(3), 470. https://doi.org/10.3390/pathogens12030470

Publication

Pathogens (Basel, Switzerland)
ISSN: 2076-0817
NlmUniqueID: 101596317
Country: Switzerland
Language: English
Volume: 12
Issue: 3
PII: 470

Researcher Affiliations

Traversa, Donato
  • Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Milillo, Piermarino
  • Azienda Sanitaria Locale (A.S.L.), 75100 Matera, Italy.
Maggi, Raffaella
  • Freelance Veterinary Practitioner, 00189 Rome, Italy.
Simonato, Giulia
  • Department of Animal Medicine, Production and Health, University of Padua, 35020 Legnaro, Italy.
Di Cesare, Angela
  • Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Pezzuto, Carlo
  • Ambulatorio Veterinario Pezzuto Carlo/Piano Noemi, 86010 Campobasso, Italy.
Grillini, Marika
  • Department of Animal Medicine, Production and Health, University of Padua, 35020 Legnaro, Italy.
Morelli, Simone
  • Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Colombo, Mariasole
  • Department of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Passarelli, Alessandra
  • Clinica Veterinaria Città di Bari, 70125 Bari, Italy.
Grassano, Antonio
  • Freelance Veterinary Practitioner, 75020 Nova Siri, Italy.
Serio, Paola
  • Azienda Sanitaria Locale (A.S.L.), 75100 Matera, Italy.
Losurdo, Michele
  • Azienda Sanitaria Locale (A.S.L.), 75100 Matera, Italy.
Brueckmann, Roberto
  • EUROIMMUN Medizinische Labordiagnostika AG, 23560 Lübeck, Germany.

Grant Funding

  • N/A / Euroimmun Medizinische Labordiagnostika (Germany)

Conflict of Interest Statement

Roberto Brueckmann is an employee at EUROIMMUN Medizinische Labordiagnostika. All other authors declare no conflict of interest.

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