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[Serologic studies of the occurrence of Borrelia burgdorferi in domestic animals in Berlin (West)].

Abstract: The prevalence of B. burgdorferi, the causative agent of Lyme Borreliosis in humans, was determined in domestic animals living in Berlin. 189 dogs, 29 cats, 224 horses and 194 cows were investigated. Using the indirect immunofluorescence test (IFT) 5.8% of the dogs and 24.5% of the cows investigated showed a positive reaction at titres of 1:128 or higher. Horses and cats gave negative results. ELISA was more sensitive than IFT. 10.1% of the dogs, 16.1% of the horses and 66% of the local cows showed positive reaction. Domestic animals seem to be in contact with B. burgdorferi and can be a reservoir for the spirochete. Also there is the possibility that domestic animals get clinically ill.
Publication Date: 1990-11-01 PubMed ID: 2268252
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  • English Abstract
  • Journal Article

Summary

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The research article investigates the prevalence of Borrelia burgdorferi, the bacteria causing Lyme disease, in domesticated animals (dogs, cats, horses, and cows) in Berlin.

Research Methodology

  • The researchers conducted serologic tests on a number of domestic animals, including 189 dogs, 29 cats, 224 horses, and 194 cows in Berlin.
  • The two testing methods used were the indirect immunofluorescence test (IFT) and ELISA (Enzyme-Linked Immunosorbent Assay).
  • The IFT identifies if an animal’s immune system has produced antibodies against Borrelia burgdorferi, which would indicate exposure to the bacterium.
  • ELISA is another type of test that detects antibodies to the bacterium, but it is generally considered more sensitive than the IFT.

Research Findings

  • The immunofluorescence test (IFT) showed positive results indicating the presence of B. burgdorferi for 5.8% of the dogs and 24.5% of the cows, while all horses and cats tested negative.
  • ELISA tests showed a higher percentage of positive results, with 10.1% of the dogs, 16.1% of the horses, and 66% of the cows testing positive.
  • The discrepancy between the IFT and ELISA results is likely due to the higher sensitivity of the ELISA test.

Research Conclusions

  • The study concludes that domestic animals — particularly cows — in Berlin are in contact with B. burgdorferi and could act as reservoirs for the bacteria, increasing the risk of transmission to humans.
  • The study also suggests the possibility that domestic animals could become sick as a result of exposure to B. burgdorferi.
  • This research provides important insights into potential public health risks, especially related to Lyme disease transmission from animals to humans, in urban environments.

Cite This Article

APA
Käsbohrer A, Schönberg A. (1990). [Serologic studies of the occurrence of Borrelia burgdorferi in domestic animals in Berlin (West)]. Berl Munch Tierarztl Wochenschr, 103(11), 374-378.

Publication

ISSN: 0005-9366
NlmUniqueID: 0003163
Country: Germany
Language: ger
Volume: 103
Issue: 11
Pages: 374-378

Researcher Affiliations

Käsbohrer, A
  • Institut für Veterinärmedizin Robert von Ostertag-Institut des Bundesgesundheitsamtes, Berlin.
Schönberg, A

    MeSH Terms

    • Animals
    • Animals, Domestic
    • Antibodies, Bacterial / analysis
    • Berlin / epidemiology
    • Borrelia burgdorferi Group / immunology
    • Cats
    • Cattle
    • Dogs
    • Horses
    • Lyme Disease / epidemiology
    • Lyme Disease / veterinary
    • Prevalence

    Citations

    This article has been cited 8 times.
    1. Doff SC, Wenderlein J, Wiesinger A, Hiereth S, Ulrich S, Straubinger RK. Detection of Borrelia burgdorferi Sensu-Lato-Specific Antibodies in Sera of Canine and Equine Origin-A Comparative Study with Two Line Immunoassays.. Vet Sci 2022 Nov 14;9(11).
      doi: 10.3390/vetsci9110633pubmed: 36423082google scholar: lookup
    2. Bogdan AM, Ionita M, Mitrea IL. Serological Evidence of Natural Exposure to Tick-Borne Pathogens in Horses, Romania.. Microorganisms 2021 Feb 12;9(2).
      doi: 10.3390/microorganisms9020373pubmed: 33673353google scholar: lookup
    3. Springer A, Glass A, Topp AK, Strube C. Zoonotic Tick-Borne Pathogens in Temperate and Cold Regions of Europe-A Review on the Prevalence in Domestic Animals.. Front Vet Sci 2020;7:604910.
      doi: 10.3389/fvets.2020.604910pubmed: 33363242google scholar: lookup
    4. Cook MJ, Puri BK. Estimates for Lyme borreliosis infections based on models using sentinel canine and human seroprevalence data.. Infect Dis Model 2020;5:871-888.
      doi: 10.1016/j.idm.2020.10.004pubmed: 33210054google scholar: lookup
    5. Houben RMAC, Meersschaert C, Hendrickx G, Pitel PH, Amory H. Modelling the probability and impact of false-positive serology for Borrelia burgdorferi sensu lato: A case study.. Equine Vet J 2021 Jan;53(1):71-77.
      doi: 10.1111/evj.13277pubmed: 32385952google scholar: lookup
    6. Hansen MG, Christoffersen M, Thuesen LR, Petersen MR, Bojesen AM. Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in Danish horses.. Acta Vet Scand 2010 Jan 18;52(1):3.
      doi: 10.1186/1751-0147-52-3pubmed: 20082693google scholar: lookup
    7. Goossens HA, van den Bogaard AE, Nohlmans MK. Dogs as sentinels for human Lyme borreliosis in The Netherlands.. J Clin Microbiol 2001 Mar;39(3):844-8.
      doi: 10.1128/JCM.39.3.844-848.2001pubmed: 11230393google scholar: lookup
    8. Delgado S, Cármenes P. Seroepidemiological survey for Borrelia burgdorferi (Lyme disease) in dogs from northwestern of Spain.. Eur J Epidemiol 1995 Jun;11(3):321-4.
      doi: 10.1007/BF01719437pubmed: 7493665google scholar: lookup