FREE SHIPPING over $40
OVER 9000 FIVE-STAR REVIEWS
5% OFF ALL SUBSCRIPTIONS
100% HAPPINESS GUARANTEE
Analyze Diet
0
Home / Equine Research Bank / Trop Anim Health Prod / Serological survey for Brucella antibodies in donkeys of nor...
Tropical animal health and production2017; 49(6); 1211-1216; doi: 10.1007/s11250-017-1318-4

Serological survey for Brucella antibodies in donkeys of north-eastern Nigeria.

Abstract: A cross-sectional epidemiological study was conducted to determine seroprevalence and risk factors influencing the presence of Brucella antibodies in donkeys of Borno State, north-eastern Nigeria. The study aimed at providing baseline information that may be used in planning a control policy against equine brucellosis. Blood samples were collected from 601 donkeys, comprised of 374 males and 227 females from the six agricultural zones of the state between March 2013 and September 2014. The sera obtained were tested for Brucella antibodies using Rose Bengal plate test (RBPT) and competitive enzyme-linked immunosorbent assay (cELISA). Of the 601 donkeys tested, 43 (7.2%) and 40 (6.7%) were seropositive by RBPT and cELISA, respectively. A seroprevalence of 8.6% was obtained in male and 3.5% in female donkeys. According to age, the highest seroprevalence of 9.6% was obtained from donkeys of age group 4-6 years. With respect to pregnancy status, a higher seroprevalence (6.8%) was obtained from pregnant donkeys compared to 3.8% obtained from the non-pregnant ones. There were statistically significant associations between the presence of antibodies and sex (p < 0.05) and the presence of antibodies and age (p  0.05) was observed between the pregnancy status and presence of antibodies. The study concludes that Brucella infection is present in donkeys in all the agricultural zones of the state. The relatively high seroprevalence (7.2%) obtained is of public health concern because of the close interaction between donkeys, ruminants, and humans in the study area.
Get Full Text
Publication Date: 2017-06-14 PubMed ID: 28616790DOI: 10.1007/s11250-017-1318-4Google Scholar: Lookup
The Equine Research Bank provides access to a large database of publicly available scientific literature. Inclusion in the Research Bank does not imply endorsement of study methods or findings by Mad Barn.
LinkedInCopy
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article focuses on a study carried out to determine the presence and influence of Brucella antibodies in donkeys found in north-eastern Nigeria. The study was aimed at gathering information to help in planning control policies against donkey brucellosis.

Study Methodology

  • The research was a cross-sectional epidemiological study conducted in Borno State in north-eastern Nigeria.
  • The study involved collection of blood samples from 601 donkeys, which consisted of 374 males and 227 females.
  • The samples were taken from six different agricultural zones within the state, over a period of one and a half years from March 2013 to September 2014.
  • The blood samples were tested for the presence of Brucella antibodies using two methods; the Rose Bengal plate test (RBPT) and the competitive enzyme-linked immunosorbent assay (cELISA).

Study Findings

  • Out of the 601 donkeys tested, 43 (7.2%) and 40 (6.7%) were found to be positive for Brucella antibodies according to the RBPT and cELISA tests respectively.
  • The seroprevalence was higher in male donkeys (8.6%) than in female donkeys (3.5%).
  • Donkeys within the age group of 4-6 years had the highest seroprevalence of 9.6%.
  • Pregnant donkeys had a higher seroprevalence (6.8%) compared to non-pregnant ones (3.8%).
  • There were statistically significant associations between the presence of Brucella antibodies and both the sex and age of the donkeys.
  • No significant association was found between the pregnancy status of the donkeys and the presence of antibodies.

Conclusion and Implications

  • The study concludes that Brucella infection is present in donkeys across all the agricultural zones within the state.
  • The high seroprevalence of 7.2% is a concern for public health due to the close interaction between donkeys, ruminants, and humans in the study area.
  • These findings could be useful for forming a control policy for equine brucellosis, thereby preventing its spread and impact on public health.

Cite This Article

APA
Tijjani AO, Junaidu AU, Salihu MD, Farouq AA, Faleke OO, Adamu SG, Musa HI, Hambali IU. (2017). Serological survey for Brucella antibodies in donkeys of north-eastern Nigeria. Trop Anim Health Prod, 49(6), 1211-1216. https://doi.org/10.1007/s11250-017-1318-4

Publication

Tropical animal health and production
ISSN: 1573-7438
NlmUniqueID: 1277355
Country: United States
Language: English
Volume: 49
Issue: 6
Pages: 1211-1216

Researcher Affiliations

Tijjani, A O
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria. olawa89@gmail.com.
Junaidu, A U
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria.
Salihu, M D
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria.
Farouq, A A
  • Department of Microbiology, Faculty of Science, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria.
Faleke, O O
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University, Sokoto, Sokoto State, Nigeria.
Adamu, S G
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.
Musa, H I
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.
Hambali, I U
  • Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.

MeSH Terms

  • Animals
  • Brucella / isolation & purification
  • Brucellosis / epidemiology
  • Brucellosis / microbiology
  • Brucellosis / veterinary
  • Cross-Sectional Studies
  • Enzyme-Linked Immunosorbent Assay / veterinary
  • Equidae
  • Female
  • Male
  • Nigeria / epidemiology
  • Pregnancy
  • Prevalence
  • Risk Factors
  • Rose Bengal / metabolism
  • Seroepidemiologic Studies

References

This article includes 11 references
  1. Abo-Shehada MN. Seroprevalence of Brucella species in equids in Jordan.. Vet Rec 2009 Aug 29;165(9):267-8.
    pubmed: 19717833doi: 10.1136/vr.165.9.267google scholar: lookup
  2. Ehizibolo DO, Gusi AM, Ehizibolo PO, Mbuk EU, Ocholi RA. Serologic prevalence of brucellosis in horse stables in two northern States of Nigeria.. J Equine Sci 2011;22(1):17-9.
    pubmed: 24833983doi: 10.1294/jes.22.*17google scholar: lookup
  3. Haileselassie M, Kalayou S, Kyule M, Asfaha M, Belihu K. Effect of Brucella infection on reproduction conditions of female breeding cattle and its public health significance in Western tigray, northern ethiopia.. Vet Med Int 2011;2011:354943.
    pubmed: 21822466doi: 10.4061/2011/354943google scholar: lookup
  4. Mai HM, Irons PC, Kabir J, Thompson PN. A large seroprevalence survey of brucellosis in cattle herds under diverse production systems in northern Nigeria.. BMC Vet Res 2012 Aug 25;8:144.
    pubmed: 22920578doi: 10.1186/1746-6148-8-144google scholar: lookup
  5. Cadmus SI, Adesokan HK, Ajala OO, Odetokun WO, Perrett LL, Stack JA. Seroprevalence of Brucella abortus and B. canis in household dogs in southwestern Nigeria: a preliminary report.. J S Afr Vet Assoc 2011 Mar;82(1):56-7.
    pubmed: 21826840doi: 10.4102/jsava.v82i1.35google scholar: lookup
  6. Matope G, Bhebhe E, Muma JB, Lund A, Skjerve E. Risk factors for Brucella spp. infection in smallholder household herds.. Epidemiol Infect 2011 Jan;139(1):157-64.
    pubmed: 20478082doi: 10.1017/S0950268810000968google scholar: lookup
  7. Chimana HM, Muma JB, Samui KL, Hangombe BM, Munyeme M, Matope G, Phiri AM, Godfroid J, Skjerve E, Tryland M. A comparative study of the seroprevalence of brucellosis in commercial and small-scale mixed dairy-beef cattle enterprises of Lusaka province and Chibombo district, Zambia.. Trop Anim Health Prod 2010 Oct;42(7):1541-5.
    pubmed: 20517646doi: 10.1007/s11250-010-9604-4google scholar: lookup
  8. Ibrahim N, Belihu K, Lobago F, Bekana M. Sero-prevalence of bovine brucellosis and its risk factors in Jimma zone of Oromia Region, South-western Ethiopia.. Trop Anim Health Prod 2010 Jan;42(1):35-40.
    pubmed: 19543803doi: 10.1007/s11250-009-9382-zgoogle scholar: lookup
  9. Ocholi RA, Bertu WJ, Kwaga JK, Ajogi I, Bale JO, Okpara J. Carpal bursitis associated with Brucella abortus in a horse in Nigeria.. Vet Rec 2004 Oct 30;155(18):566-7.
    pubmed: 15559426doi: 10.1136/vr.155.18.566google scholar: lookup
  10. Hussein AA, Sayed AS, El Feki MA. Seroepidemiological study on human brucellosis in Assiut Governorate.. Egypt J Immunol 2005;12(1):49-56.
    pubmed: 16734139
  11. Santellano-Estrada E, Infante F, Díaz-Aparicio E, Flores-Gutiérrez GH. Use of an immunobinding test on nitrocellulose paper to diagnose caprine brucellosis.. Vet Res Commun 2004 Jan;28(1):27-31.
    pubmed: 14989360doi: 10.1023/b:verc.0000009532.11237.77google scholar: lookup

Citations

This article has been cited 8 times.
  1. Hussain R, Khan I, Jamal A, Mohamed BB, Khan A. Evaluation of Hematological, Oxidative Stress, and Antioxidant Profile in Cattle Infected with Brucellosis in Southern Punjab, Pakistan. Biomed Res Int 2022;2022:7140909.
    doi: 10.1155/2022/7140909pubmed: 35898677google scholar: lookup
  2. Akinyemi KO, Fakorede CO, Amisu KO, Wareth G. Human and Animal Brucellosis in Nigeria: A Systemic Review and Meta-Analysis in the Last Twenty-One Years (2001-2021). Vet Sci 2022 Jul 26;9(8).
    doi: 10.3390/vetsci9080384pubmed: 35893777google scholar: lookup
  3. Hussain A, Jamil T, Tareen AM, Melzer F, Hussain MH, Khan I, Saqib M, Zohaib A, Hussain R, Ahmad W, Iqbal M, Neubauer H. Serological and Molecular Investigation of Brucellosis in Breeding Equids in Pakistani Punjab. Pathogens 2020 Aug 19;9(9).
    doi: 10.3390/pathogens9090673pubmed: 32825067google scholar: lookup
  4. Adamu SG, Hassan M, Ardo MB. Seroprevalence of Brucella antibodies in Donkeys (Equus asinus) in Yobe south senatorial zone, Northeastern Nigeria. J Equine Sci 2020 Mar;31(1):5-10.
    doi: 10.1294/jes.31.5pubmed: 32206033google scholar: lookup
  5. Adamu SG, Kabir J, Umoh JU, Raji MA. Seroprevalence of brucellosis and Q fever (Coxiellosis) in cattle herds in Maigana and Birnin Gwari agro-ecological zone of Kaduna State, Nigeria. Trop Anim Health Prod 2018 Oct;50(7):1583-1589.
    doi: 10.1007/s11250-018-1598-3pubmed: 29675780google scholar: lookup
  6. Gao W, Liu M, Nurdaly K, Caidan D, Sun Y, Duan J, Zhao J, Gong X, Zhou J, Zhang Y, Chen Q. Unveiling Equine Abortion Pathogens: A One Health Perspective on Prevalence and Resistance in Northwest China. Pathogens 2025 Dec 11;14(12).
    doi: 10.3390/pathogens14121275pubmed: 41471229google scholar: lookup
  7. Kithuka JM, Wachira TM, Onono JO, Ngetich W. The burden of brucellosis in donkeys and its implications for public health and animal welfare: A systematic review and meta-analysis. Vet World 2025 Feb;18(2):367-378.
    doi: 10.14202/vetworld.2025.367-378pubmed: 40182828google scholar: lookup
  8. Wang Z, Zeng S, Wang Y, Wang T, Qu H, Zhu Y, Li J. Reproductive Disorders in Donkeys: Current Evidence and Update. Animals (Basel) 2024 Aug 28;14(17).
    doi: 10.3390/ani14172494pubmed: 39272279google scholar: lookup
Subscribe to our newsletter
Join 99,357 horse owners like you who receive our email updates on horse health and nutrition.