Serum amino acid profiles in clinically normal Noma horses.
Abstract: Plasma or serum amino acids are used to evaluate nutritional status and metabolic disorders. In this study, we aimed to set reference values of serum amino acid concentrations in the Noma horse, a Japanese native horse. Thirty-one horses were classified into six age groups: neonatal foal (0-4 days), foal (0.5-1 years), youth (5 years), middle age (10 years), old (15 years), and extra-old (>20 years). Horses >5 years of age were analyzed together as the adult group. In the adult horses, there were no significant differences among the serum amino acid concentrations of each age group. The foal group had higher concentrations of alanine, aspartic acid, glutamic acid, α-aminoadipic acid, and 3-methyl-histidine than the adult group. The neonatal foal group had higher serum concentrations of phenylalanine, lysine, alanine, proline, aspartic acid, glutamic acid, β-alanine, and β-amino-iso-butyric acid and lower tryptophan concentrations and Fischer's ratios than the adult group. The neonatal foal group had higher β-amino-iso-butyric acid concentrations and lower tryptophan and 3-methyl-histidine concentrations than the foal group. Therefore, reference values might be set separately in neonatal foals, foals, and adult horses. The data for the serum amino acid concentrations can be used for health care through physiological and pathological evaluations in Noma horses.
©2024 The Japanese Society of Equine Science.
Publication Date: 2024-07-03 PubMed ID: 38962514PubMed Central: PMC11219156DOI: 10.1294/jes.35.29Google Scholar: Lookup
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Summary
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The research article describes a study that aimed to establish reference values for serum amino acid concentrations in the Noma horse, a breed native to Japan. The study observed differences in the concentration of these amino acids in horses grouped by age, and suggests that age-specific reference values may be necessary.
Objective of the Study
- The study pursued the goal of setting reference values for serum amino acid concentrations in Noma horses.
- The serum amino acid concentration values can be employed to assess a horse’s nutritional status and potential metabolic disorders, important factors in managing the health and welfare of these animals.
Methodology
- The research involved an evaluation of 31 Noma horses segregated into six different age groups: neonatal foal (0-4 days old), foal (0.5-1 years old), youth (at 5 years old), middle age (10 years old), old (15 years old), and extra-old (over 20 years old).
- Horses older than 5 years were analyzed jointly as the adult group.
Findings
- Overall, there were no significant differences in the serum amino acid concentrations amongst the different age categories of adult horses.
- The foal group exhibited higher concentrations of several amino acids (alanine, aspartic acid, glutamic acid, α-aminoadipic acid, and 3-methyl-histidine) than the adult group.
- Neonatal foals had higher levels of several amino acids (including phenylalanine, lysine, alanine, proline, aspartic acid, glutamic acid, β-alanine, and β-amino-iso-butyric acid) and lower levels of tryptophan and Fischer’s ratios than the adult group.
- Comparing the neonatal foal group with the slightly older foal group revealed that neonates had higher β-amino-iso-butyric acid concentrations and lower tryptophan and 3-methyl-histidine levels.
Conclusions
- This research implies that the reference values for serum amino acid concentrations might be set differently according to age groups among neonatal foals, foals, and adult horses.
- The data collected can prove valuable in ongoing health care of Noma horses, enabling more nuanced physiological and pathological evaluations.
Cite This Article
APA
Hisaeda K, Ono T, Kadekaru S, Hata A, Miyama TS, Kutara K, Sugimoto K, Hiasa Y, Ohzawa E, Kunieda T, Iwata E, Kitagawa H.
(2024).
Serum amino acid profiles in clinically normal Noma horses.
J Equine Sci, 35(2), 29-34.
https://doi.org/10.1294/jes.35.29 Publication
Researcher Affiliations
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshda, Yamaguchi 753-8515, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Hiasa Animal Clinic, 2-6-8 Koushouji, Imabari, Ehime 794-0805, Japan.
- Noma Horse Preservation Society, 8 Nomakou, Imabari, Ehime 794-0082, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
- Faculty of Veterinary Medicine, Okayama University of Science, 1-3 Ikoino-oka, Imabari, Ehime 794-8555, Japan.
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