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Small intestine adenocarcinoma in conjunction with multiple adenomas causing acute colic in a horse.

Abstract: An 11-year-old Andalusian stallion developed marked signs of colic associated with an acute small intestine obstruction. Exploratory laparotomy revealed a distal jejunum full-thickness wall induration and multiple small adherent intraluminal masses. Fifteen centimeters of jejunum, including the induration, and several intraluminal masses were resected. Histologic examination revealed an adenocarcinoma and multiple polypoid adenomas. The horse was discharged, and no complications were reported 12 months postoperatively. Colic was considered secondary to partial jejunal lumen obstruction by the adenocarcinoma. Adenocarcinoma recurrence or transformation from remaining adenomas into an adenocarcinoma is still a major risk.
Publication Date: 2008-01-10 PubMed ID: 18182527DOI: 10.1177/104063870802000128Google Scholar: Lookup
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  • Journal Article

Summary

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The article discusses a case where an 11-year-old horse developed severe gastrointestinal discomfort (colic), which was found to be due to cancerous and non-cancerous tumors in the small intestine. After surgery to remove the tumors, the horse showed no complications a year later, but there is still a high risk of the cancer returning or of the benign tumors developing into cancer.

Background and Case Presentation

  • An 11-year-old Andalusian stallion shows severe signs of colic, an affliction in horses described by signs of abdominal discomfort. The colic was linked to an acute blockage within the horse’s small intestine.
  • An exploratory surgery called a laparotomy revealed that the cause of the blockage was a hardened part of Jejunum wall which is a mid-section of the small intestine, and several small masses attached inside the Jejunum.

Surgical Intervention and Diagnosis

  • During the surgical process, a 15-centimeter section of the Jejunum, which had turned hard and encompassed the small masses, was removed by the veterinarians.
  • The resected masses and parts of the intestine were examined histologically through which they were diagnosed to be an adenocarcinoma – a type of cancer that forms in mucus-secreting glands – and multiple polypoid adenomas – benign growths that may become cancerous.

Postoperative Phase and Future Risks

  • The horse was discharged after its operation and displayed no complications or issues a full year after the surgery occurred.
  • However, the occurrence of colic is believed to be a consequence of the partial blockage of the Jejunum lumen caused by the adenocarcinoma.
  • Despite the successful surgery and apparent recuperation, there is still a high possibility that the adenocarcinoma could reappear or the remaining adenomas might transform into an adenocarcinoma.

Cite This Article

APA
Moran JA, Lemberger K, Cadoré JL, Lepage OM. (2008). Small intestine adenocarcinoma in conjunction with multiple adenomas causing acute colic in a horse. J Vet Diagn Invest, 20(1), 121-124. https://doi.org/10.1177/104063870802000128

Publication

ISSN: 1040-6387
NlmUniqueID: 9011490
Country: United States
Language: English
Volume: 20
Issue: 1
Pages: 121-124

Researcher Affiliations

Moran, Juan A Muñoz
  • Equine Department, Ecole Nationale Vétérinaire de Lyon, 1, Avenue Bourgelat, 69280 Marcy L'Etoile, France. jamunozmoran@yahoo.es
Lemberger, Karin
    Cadoré, Jean-Luc
      Lepage, Olivier M

        MeSH Terms

        • Adenocarcinoma / pathology
        • Adenocarcinoma / surgery
        • Adenocarcinoma / veterinary
        • Animals
        • Colic / pathology
        • Colic / surgery
        • Colic / veterinary
        • Histocytochemistry / veterinary
        • Horse Diseases / pathology
        • Horse Diseases / surgery
        • Horses
        • Intestinal Neoplasms / pathology
        • Intestinal Neoplasms / surgery
        • Intestinal Neoplasms / veterinary
        • Intestine, Small / pathology
        • Intestine, Small / surgery
        • Male

        Citations

        This article has been cited 2 times.
        1. Nolf M, Maninchedda U, Belluco S, Lepage O, Cadoré JL. Cecal vascular hamartoma causing recurrent colic in an Arabian mare. Can Vet J 2014 Jun;55(6):547-50.
          pubmed: 24891636
        2. Malberg JA, Webb BT, Hackett ES. Colonic gastrointestinal stromal tumor resulting in recurrent colic and hematochezia in a warmblood gelding. Can Vet J 2014 May;55(5):471-4.
          pubmed: 24790234