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Sonographic findings in horses with mediastinal lymphosarcoma: 13 cases (1985-1992).

Abstract: Sonographic findings correlated with necropsy findings in 8 of 9 horses in which the cranial portion of the mediastinum was evaluated by use of both methods. Cranial mediastinal masses were imaged as multilobular and homogeneously hypoechoic; a complex echogenic pattern was observed with necrosis within the mass. Pleural effusion was a common finding in horses with mediastinal lymphosarcoma. Cytologic evaluation of pleural fluid samples was useful in diagnosis of lymphosarcoma in 10 of 12 horses that had thoracentesis. Sonographic examination of the thorax and cranial portion of the mediastinum can aid in the diagnosis of mediastinal lymphosarcoma in horses. Such examination should be performed in horses with clinical signs of cranial vena cava obstruction in which pleural effusion is detected, or when thoracic lymphosarcoma is suspected.
Publication Date: 1994-11-15 PubMed ID: 7698925
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  • Comparative Study
  • Journal Article

Summary

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This research article explores the use of sonography in diagnosing mediastinal lymphosarcoma in horses. The study’s findings suggest that sonographic examination can be a useful diagnostic tool, especially when there are signs of cranial vena cava obstruction or suspected thoracic lymphosarcoma.

Key Findings

  • In 8 out of 9 cases, the sonographic findings matched the necropsy findings when the cranial portion of the mediastinum was evaluated using both methods. This indicates that sonography can be an accurate diagnostic tool in these kinds of cases.
  • Cranial mediastinal masses were imaged as multilobular and homogeneously hypoechoic, with a complex echogenic pattern observed in cases of necrosis within the mass. This suggests that sonography can provide detailed images helpful in diagnosing mediastinal lymphosarcoma.
  • Pleural effusion, an excess of fluid in the pleural cavity, was commonly observed in horses suffering from mediastinal lymphosarcoma, indicating it can be a significant sign of this disease.
  • Out of 12 instances of thoracentesis, cytologic evaluation of pleural fluid samples helped diagnose lymphosarcoma in 10 cases, supporting the idea that fluid sample analysis can be a crucial part of the diagnostic process.

Implications and Recommendations

  • The researchers recommend sonographic examination of the thorax and cranial section of the mediastinum as a means to diagnose mediastinal lymphosarcoma in horses. This is particularly recommended for horses showing clinical signs of cranial vena cava obstruction or when thoracic lymphosarcoma is suspected.
  • The study highlights the importance of cytologic evaluation of pleural fluid samples, as it was found to be useful in diagnosis in a majority of thoracentesis cases. Therefore, whenever pleural effusion is detected, a thoracentesis to obtain fluid samples for cytologic evaluation should be considered.

Conclusion

  • The research indicates the potential usefulness of sonographic examination in diagnosing mediastinal lymphosarcoma in horses. Combined with cytologic evaluation of pleural fluid samples, sonography can provide a more accurate and timely diagnosis, thus leading to quicker and potentially more effective treatments.

Cite This Article

APA
Garber JL, Reef VB, Reimer JM. (1994). Sonographic findings in horses with mediastinal lymphosarcoma: 13 cases (1985-1992). J Am Vet Med Assoc, 205(10), 1432-1436.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 205
Issue: 10
Pages: 1432-1436

Researcher Affiliations

Garber, J L
  • George D. Widener Hospital, Section of Medicine, New Bolton Center, University of Pennsylvania, Kennett Square 19348.
Reef, V B
    Reimer, J M

      MeSH Terms

      • Animals
      • Female
      • Horse Diseases / diagnostic imaging
      • Horse Diseases / pathology
      • Horses
      • Lymphoma, Non-Hodgkin / diagnostic imaging
      • Lymphoma, Non-Hodgkin / pathology
      • Lymphoma, Non-Hodgkin / veterinary
      • Male
      • Mediastinal Neoplasms / diagnostic imaging
      • Mediastinal Neoplasms / pathology
      • Mediastinal Neoplasms / veterinary
      • Retrospective Studies
      • Ultrasonography
      • Videotape Recording

      Citations

      This article has been cited 1 times.
      1. Lawn K. Sudden death due to thoracic lymphoma in a standardbred racing horse. Can Vet J 2005 Jun;46(6):528-9.
        pubmed: 16048014