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Home / Equine Research Bank / J Vet Sci / Speckle-tracking analysis of myocardial deformation in corre...
Journal of veterinary science2018; 19(5); 676-682; doi: 10.4142/jvs.2018.19.5.676

Speckle-tracking analysis of myocardial deformation in correlation to age in healthy horses.

Abstract: An effect of aging on cardiac morphology and function has been shown in humans. In horses, cardiac wall motion analysis using two-dimensional speckle tracking (2D-ST) has not yet been reported. Our study included 57 horses of different warmblood breeds between 3 and 30 years old. Age had a significant influence on left ventricular free wall (LVFW) systolic strain rate ( ≤ 0.05) and early diastolic relaxation ( ≤ 0.01). In the interventricular septum (IVS), systolic ( ≤ 0.01) and late diastolic ( ≤ 0.05) contraction velocities also increased with age. In our study, 2D-ST revealed important information on myocardial function, which was most evident in the LVFW, where measurements were highly reproducible. Aging seems to be associated with structural changes within the myocardium and with decreasing contraction capacity in old animals. These physiological, age-related processes should be considered when performing cardiac wall motion analysis of the 2D-ST results for the LVFW and IVS in horses.
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Publication Date: 2018-04-27 PubMed ID: 29695144PubMed Central: PMC6167342DOI: 10.4142/jvs.2018.19.5.676Google Scholar: Lookup
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  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The article presents research into how aging impacts cardiac health in horses, focusing particularly on the left ventricular free wall and the interventricular septum. Using two-dimensional speckle tracking, the research shows that aging increases systolic strain rate and early diastolic relaxation in the heart.

Overview of the Research

  • The research examined cardiac morphology and function in relation to age in horses, building upon previous findings in similar human studies.
  • 57 horses of various warmblood breeds were included, aged between 3 and 30 years old.
  • The teams used two-dimensional speckle tracking (2D-ST), a tool used for cardiac wall motion analysis. This technology has not been previously reported on within this context.

Cardiac Changes With Age

  • The study found significant effects of aging on two particular aspects of cardiac function in the horses, namely the left ventricular free wall (LVFW) and the interventricular septum (IVS).
  • For the LVFW, there was a notable increase in both the systolic strain rate (significance level ≤ 0.05) and the rate of early diastolic relaxation (significance level ≤ 0.01) with aging.
  • In the IVS, increases were observed in both the systolic contraction velocities (significance level ≤ 0.01) and the late diastolic contraction velocities (significance level ≤ 0.05).

Implications and Conclusions

  • The 2D-ST revealed significant information concerning myocardial function, particularly noticeable in the LVFW where measurements were easily reproducible.
  • According to the research, aging appears to be linked with structural changes within the heart muscle, and this is associated with a decreasing contraction capacity in older animals.
  • This novel understanding of the physiological, age-related processes in equine cardiac health should be taken into account when performing cardiac wall motion analysis, especially when reviewing 2D-ST results for the LVFW and IVS in horses.

Cite This Article

APA
Gehlen H, Bildheim LM. (2018). Speckle-tracking analysis of myocardial deformation in correlation to age in healthy horses. J Vet Sci, 19(5), 676-682. https://doi.org/10.4142/jvs.2018.19.5.676

Publication

Journal of veterinary science
ISSN: 1976-555X
NlmUniqueID: 100964185
Country: Korea (South)
Language: English
Volume: 19
Issue: 5
Pages: 676-682

Researcher Affiliations

Gehlen, Heidrun
  • Equine Clinic, Freie Universitaet Berlin, 14195 Berlin, Germany.
Bildheim, Lisa-Marie
  • Equine Clinic, Freie Universitaet Berlin, 14195 Berlin, Germany.

MeSH Terms

  • Aging
  • Animals
  • Echocardiography / veterinary
  • Female
  • Horses / physiology
  • Male
  • Myocardium / pathology
  • Ventricular Function, Left

Conflict of Interest Statement

The authors declare no conflicts of interest.

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  3. Decloedt A, Ven S, De Clercq D, Rademakers F, van Loon G. Assessment of left ventricular function in horses with aortic regurgitation by 2D speckle tracking. BMC Vet Res 2020 Mar 20;16(1):93.
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