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Skeletal radiology1989; 18(2); 99-107; doi: 10.1007/BF00350656

Spinal hyperostosis in comparative pathology. A useful approach to the concept.

Abstract: Spinal hyperostosis, an anatomical and radiological concept primarily described in man, is characterized by enthesopathic bony overgrowth on vertebral bodies in the form of spurs or intervertebral bridges. It can also be part of a more diffuse enthesopathic condition, including the appendicular skeleton. These changes are distinct from those of osteoarthrosis. Similar changes can be observed in all kinds of mammals, independent of their type of locomotion (bipodic, quadrumanous, quadrupedic, or aquatic). An anatomical and radiological study is presented of six cases (with histological examination of two dogs and one horse, and observation of macerated specimens of one horse, one equida, and one whale). Comparative pathology allows for a better understanding of the concept of hyperostosis and, even more clearly than in man, this can be distinguished from that of discovertebral pathology although both conditions could be associated in older subjects. The knowledge of spinal hyperostosis in veterinary medicine could--as in man--be of interest to differentiate between this process and other features of vertebral pathology.
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Publication Date: 1989-01-01 PubMed ID: 2717963DOI: 10.1007/BF00350656Google Scholar: Lookup
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  • Comparative Study
  • Journal Article
  • Research Support
  • Non-U.S. Gov't

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article studies the phenomenon of spinal hyperostosis, which is the excessive growth of bone on the vertebral bodies in the spine, often in the form of spurs or bridges. The authors compare cases from different mammals to aid our understanding of this condition.

Understanding Spinal Hyperostosis

Spinal hyperostosis is primarily described in humans and manifests as enthesopathic bony overgrowth on the vertebral bodies. It is not restricted to the spine alone but can extend to more diffuse enthesopathic conditions that include the appendicular skeleton. The features of this condition differ significantly from osteoarthrosis.

Spinal Hyperostosis in Different Mammals

  • The authors note that spinal hyperostosis occurs across a variety of mammals, irrespective of the type of locomotion they employ, such as bipedal, quadrumanous (using four limbs for grasping), quadrupedal (four-footed), or aquatic movements.
  • An anatomical and radiological study of six cases, including two dogs, a horse, an equida (a member of the horse family), and a whale, was conducted. This involved histological examinations and observations of macerated specimens.

Applying Comparative Pathology

  • The researchers use comparative pathology – that is, the study of the nature and cause of disease in different species – to improve our understanding of hyperostosis.
  • They found that in animals, spinal hyperostosis stands out even more distinctly from discovertebral pathology (disease conditions related to the intervertebral disc and the vertebral body) than in humans, though they often coexist in older individuals.

Implications for Veterinary Medicine

Just as in human medicine, understanding spinal hyperostosis may be of importance in veterinary medicine, particularly in differentiating this condition from other kinds of vertebral pathology. This knowledge could provide useful insights for clinical diagnosis and treatment of animals suffering from spinal issues, contributing to better health outcomes.

Cite This Article

APA
Lagier R. (1989). Spinal hyperostosis in comparative pathology. A useful approach to the concept. Skeletal Radiol, 18(2), 99-107. https://doi.org/10.1007/BF00350656

Publication

Skeletal radiology
ISSN: 0364-2348
NlmUniqueID: 7701953
Country: Germany
Language: English
Volume: 18
Issue: 2
Pages: 99-107

Researcher Affiliations

Lagier, R
  • Department of Pathology (Osteoarticular Unit), Geneva Medical School, Switzerland.

MeSH Terms

  • Animals
  • Cetacea / anatomy & histology
  • Dog Diseases / pathology
  • Dogs
  • Horse Diseases / pathology
  • Horses
  • Male
  • Spinal Osteophytosis / pathology
  • Spinal Osteophytosis / veterinary
  • Spine / pathology
  • Whales / anatomy & histology

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Citations

This article has been cited 3 times.
  1. Pillai S, Littlejohn G. Metabolic factors in diffuse idiopathic skeletal hyperostosis - a review of clinical data. Open Rheumatol J 2014;8:116-28.
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  2. François RJ, Eulderink F, Bywaters EG. Commented glossary for rheumatic spinal diseases, based on pathology. Ann Rheum Dis 1995 Aug;54(8):615-25.
    doi: 10.1136/ard.54.8.615pubmed: 7677436google scholar: lookup
  3. Lagier R. The rheumatologist facing anatomical pathology. Clin Rheumatol 1990 Dec;9(4):447-51.
    doi: 10.1007/BF02030505pubmed: 2088642google scholar: lookup
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