Studies on the strongyle egg output of horses after treatment with oxfendazole (Synanthic vet. Syntex).

The article evaluates the effect of the medicine oxfendazole on reducing the number of strongyle eggs (a type of parasite) produced by horses.

Objective of the Study

• The purpose of this research was to study the effect of the anthelmintic (anti-parasitic) drug oxfendazole on the strongyle egg output in horses affected by strongylosis (an infection caused by strongyle parasites). The drug was administered either as an oral paste or as pellets mixed in food.

Methodology of the Study

• Oxfendazole was given to the horses in two forms: as an 18.5% concentration paste or as 6.48% pellets mixed with feed. The dosage given to each horse was proportionate to its body weight – 46.3 grams per 300 kg of bodyweight.
• The dosage rate was maintained at 10 mg per kg of bodyweight. This is the quantity of the medication, oxfendazole, introduced into the body per kg of the bodyweight. This standardized measure ensured that every horse got an equitable amount of medicine in proportion to its size.

Results of the Study

• It was found that oxfendazole considerably reduced strongyle egg output over a 10 week period. This means that the medicine was effective in controlling the strongyle infection in the horses by reducing the number of eggs produced by these parasites.

Conclusions of the Study

• The results suggest that oxfendazole can be a valuable compound for controlling strongylosis in horses. This is because the period to egg reappearance after treatment with oxfendazole is significantly longer than that with most other anthelmintics given at recommended dose levels. Essentially, this means that oxfendazole has a more enduring effect in controlling the parasite, hence potentially offering better infection management.