Study design synopsis: Omics studies of fractures in the horse – Which technology is best?
Abstract: No abstract available
Publication Date: 2021-06-23 PubMed ID: 34161618DOI: 10.1111/evj.13467Google Scholar: Lookup
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- Editorial
Cite This Article
APA
Taylor SE, Matika O, Lee S, Baker M, Watson KA.
(2021).
Study design synopsis: Omics studies of fractures in the horse – Which technology is best?
Equine Vet J, 53(6), 1091-1093.
https://doi.org/10.1111/evj.13467 Publication
Researcher Affiliations
- The Dick Vet Equine Hospital, Midlothian, UK.
- The Roslin Institute, Midlothian, UK.
- The Roslin Institute, Midlothian, UK.
- The Roslin Institute, Midlothian, UK.
- The Roslin Institute, Midlothian, UK.
MeSH Terms
- Animals
- Fractures, Bone / genetics
- Fractures, Bone / veterinary
- Genome-Wide Association Study / veterinary
- Horse Diseases / genetics
- Horses
- Technology
Grant Funding
- vet/prj/790 / Horserace Betting Levy Board
References
This article includes 17 references
- Allen SE, Rosanowski SM, Stirk AJ, Verheyen KLP. Description of veterinary events and risk factors for fatality in National Hunt flat racing Thoroughbreds in Great Britain (2000-2013).. Equine Vet J 2017;49:700-5.
- Rosanowski SM, Chang YM, Stirk AJ, Verheyen KLP. Epidemiology of race-day distal limb fracture in flat racing Thoroughbreds in Great Britain (2000-2013).. Equine Vet J 2019;51:83-9.
- Crawford KL, Ahern BJ, Perkins NR, Phillips CJC, Finnane A. The effect of combined training and racing high-speed exercise history on musculoskeletal injuries in thoroughbred racehorses: a systematic review and meta-analysis of the current literature.. Animals (Basel) 2020;10(11):2091.
- Hitchens PL, Morrice-West AV, Stevenson MA, Whitton RC. Meta-analysis of risk factors for racehorse catastrophic musculoskeletal injury in flat racing.. Vet J 2019;245:29-40.
- Horse Welfare Board. http://media.britishhorseracing.com/bha/Welfare/HWB/WELFARE_STRATEGY.pdf. Accessed May 20, 2021.
- Varley I, Greeves JP, Sale C, Friedman E, Moran DS, Yanovich R. Functional polymorphisms in the P2X7 receptor gene are associated with stress fracture injury.. Purinergic Signal 2016;12:103-13.
- Varley I, Hughes DC, Greeves JP, Stellingwerff T, Ranson C, Fraser WD. RANK/RANKL/OPG pathway: genetic associations with stress fracture period prevalence in elite athletes.. Bone 2015;71:131-6.
- Lee S, Baker ME, Clinton M, Taylor SE. Use of omics data in fracture prediction; a scoping and systematic review in horses and humans.. Animals (Basel) 2021;11(4):959.
- Li JH, Mazur CA, Berisa T, Pickrell JK. Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays.. Genome Res 2021;31:529-37.
- Wasik K, Berisa T, Pickrell JK, Li JH, Fraser DJ, King K. Comparing low-pass sequencing and genotyping for trait mapping in pharmacogenetics.. BMC Genom 2021;22:197.
- Zondervan KT, Cardon LR. Designing candidate gene and genome-wide case-control association studies.. Nat Protoc 2007;2:2492-501.
- Blott SC, Swinburne JE, Sibbons C, Fox-Clipsham LY, Helwegen M, Hillyer L. A genome-wide association study demonstrates significant genetic variation for fracture risk in Thoroughbred racehorses.. BMC Genom 2014;15:147.
- Loos RJF. 15 years of genome-wide association studies and no signs of slowing down.. Nat Commun 2020;11:5900.
- Ryan-Moore E, Mavrommatis Y, Waldron M. systematic review and meta-analysis of candidate gene association studies with fracture risk in physically active participants.. Front Genet 2020;11:551.
- Tozaki T, Kusano K, Ishikawa Y, Kushiro A, Nomura M, Kikuchi M. A candidate-SNP retrospective cohort study for fracture risk in Japanese Thoroughbred racehorses.. Anim Genet 2020;51:43-50.
- McGivney BA, Griffin ME, Gough KF, McGivney CL, Browne JA, Hill EW. Evaluation of microRNA expression in plasma and skeletal muscle of thoroughbred racehorses in training.. BMC Vet Res 2017;13:347.
- Louisville, UO. 2018. https://www.ensembl.org/info/genome/genebuild/2019_09_equus_caballus_gene_annotation.pdf. Accessed May 20, 2021
Citations
This article has been cited 1 times.- Finno CJ. Science-in-brief: Genomic and transcriptomic approaches to the investigation of equine diseases.. Equine Vet J 2022 Mar;54(2):444-448.
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