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Clinical toxicology1972; 5(4); 567-573; doi: 10.3109/15563657208991031

Syndromes of locoweed poisoning in livestock.

Abstract: No abstract available.
Publication Date: 1972-01-01 PubMed ID: 4674446DOI: 10.3109/15563657208991031Google Scholar: Lookup
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  • Journal Article

Summary

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The research article discusses the historical problem of locoweed poisoning in livestock in the western United States—a problem initially recognized by early livestockmen. It details the origins of locoweed, highlighting its significant effects on livestock health and behavior.

Origins of Locoweed and Its Impact

  • Locoweed, belonging to the Astragalus and Oxytropis genus, was recognized as a toxic plant that adversely affected livestock in the early days of western United States farming.
  • Interestingly, ‘Loco’, a Spanish term meaning ‘foolish’ or ‘crazy’, has been used to describe both the poisonous plant and the animal subjected to its toxins—appropriately depicting the animals’ behavior upon ingestion of the plant.

First Reports and Geographical Impacts

  • The first documented instance of locoweed poisoning predates 1873. However, the Astragalus and Oxytropis plants were not scientifically linked to the poisoning until 1906.
  • In terms of geographical implications, locoweed poisoning has been primarily confined to the states lying west of the Mississippi river. This makes locoweed one of the most troublesome poisonous plants in the region for all domesticated livestock species.

Species and Viability

  • There are over 300 distinct species of Astragalus plants native to North America.
  • The Astragalus plants display high local endemicity, i.e., they are commonplace in their specific regions. This is further influenced by the astonishingly extended viability of their seeds which can remain potent for over 40 years.
  • Interestingly, its desert species do not grow annually. They germinate and grow to maturity only when environmental conditions are agreeable.

It’s evident, therefore, that locoweed is a resilient plant that poses a significant challenge to livestock health in the western United States, requiring further study to mitigate its impacts effectively.

Cite This Article

APA
James LF. (1972). Syndromes of locoweed poisoning in livestock. Clin Toxicol, 5(4), 567-573. https://doi.org/10.3109/15563657208991031

Publication

ISSN: 0009-9309
NlmUniqueID: 0205535
Country: United States
Language: English
Volume: 5
Issue: 4
Pages: 567-573

Researcher Affiliations

James, L F

    MeSH Terms

    • Anemia / chemically induced
    • Animals
    • Birds
    • Birth Weight / drug effects
    • Cats
    • Guinea Pigs
    • Horses
    • Humans
    • Nervous System Diseases / chemically induced
    • Plant Poisoning / complications
    • Plant Poisoning / enzymology
    • Plant Poisoning / veterinary
    • Plants / analysis
    • Reproduction / drug effects
    • Sheep
    • Species Specificity
    • Substance-Related Disorders

    Citations

    This article has been cited 2 times.
    1. Shi M, Li YZ. Alternaria gansuense, a Plant Systematic Fungal Pathogen Producing Swainsonine in Vivo and in Vitro.. Curr Microbiol 2023 Jun 1;80(7):232.
      doi: 10.1007/s00284-023-03341-wpubmed: 37264252google scholar: lookup
    2. Lu H, Zhang L, Wang SS, Wang WL, Zhao BY. The study of the Oxytropis kansuensis-induced apoptotic pathway in the cerebrum of SD rats.. BMC Vet Res 2013 Oct 22;9:217.
      doi: 10.1186/1746-6148-9-217pubmed: 24148892google scholar: lookup