Tapeworms as a cause of intestinal disease in horses.
Abstract: Until recently, the equine tapeworm Anoplocephala perfoliata was difficult to diagnose and considered to be of questionable pathogenicity. Here, Chris Proudman and Sandy Trees describe recent advances in the immunodiagnosis of this parasite that have facilitated epidemiological studies. These studies suggest that A. perfoliata may be an important cause of intestinal disease in the horse and demonstrate a dose-response relationship between infection intensity and risk of disease. If tapeworm infection is a risk factor for ileocaecal colic, the identification and treatment of infected individuals would be a rational approach to disease prevention.
Publication Date: 1999-05-14 PubMed ID: 10322338DOI: 10.1016/s0169-4758(99)01416-7Google Scholar: Lookup
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- Journal Article
- Research Support
- Non-U.S. Gov't
- Review
Summary
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This article explores the role of the equine tapeworm Anoplocephala perfoliata as a potential cause of intestinal diseases in horses. Recent advances in methods of immunodiagnosis have allowed for further studies to demonstrate a direct correlation between the intensity of tapeworm infection and the risk of disease. The findings also imply the possibility of preventing disease by identifying and treating infected horses.
Equine Tapeworms and Intestinal Diseases
- The primary focus of this research paper is the equine tapeworm Anoplocephala perfoliata, which until now was not only challenging to diagnose but also doubted for its pathogenic potential.
- The researchers, Chris Proudman and Sandy Trees, highlight new techniques in immunodiagnosis that have enabled more straightforward and accurate detection of this parasite.
- The paper points towards A. perfoliata as a significant cause of intestinal disease in horses, contradicting prior assumptions about its questionable pathogenicity.
Epidemiological Studies and Disease Risk
- Advancements in immunodiagnosis have not only eased the diagnosis process but also enabled profound epidemiological studies to understand the impact of A. perfoliata on horses better.
- The studies conducted, as outlined in the article, suggest a dose-response relationship between the intensity of the tapeworm infection and the risk of intestinal disease. This means that as the infection intensity increases, so does the risk of disease.
Disease Prevention Approach
- One of the significant outcomes of this research is the implication towards disease prevention in horses.
- The findings suggest that if tapeworm infection is indeed a risk factor for ileocaecal colic, an intestinal disease in horses, a logical preventative approach would be to identify horses with the infection and administer appropriate treatment.
Cite This Article
APA
Proudman CJ, Trees AJ.
(1999).
Tapeworms as a cause of intestinal disease in horses.
Parasitol Today, 15(4), 156-159.
https://doi.org/10.1016/s0169-4758(99)01416-7 Publication
Researcher Affiliations
- Equine Division, Faculty of Veterinary Science, University of Liverpool, Leahurst Neston, South Wirral, UK. chrisp@liverpool.ac.uk
MeSH Terms
- Animals
- Antibodies, Helminth / blood
- Antigens, Helminth / immunology
- Blotting, Western / veterinary
- Cestoda / immunology
- Cestoda / pathogenicity
- Cestode Infections / diagnosis
- Cestode Infections / immunology
- Cestode Infections / veterinary
- Colic / diagnosis
- Colic / immunology
- Colic / parasitology
- Colic / veterinary
- Enzyme-Linked Immunosorbent Assay / veterinary
- Horse Diseases / diagnosis
- Horse Diseases / immunology
- Horse Diseases / parasitology
- Horses
- Intestinal Diseases, Parasitic / diagnosis
- Intestinal Diseases, Parasitic / immunology
- Intestinal Diseases, Parasitic / veterinary
References
This article includes 26 references
Citations
This article has been cited 10 times.- Kukurić T, Erdeljan M, Matthews JB, Lightbody KL, Austin CJ, Peczak N, Uzelac A, Klun I, Simin S. A Prevalence Study on Anoplocephala spp. in Serbian Horses: Navigating Diagnostic Challenges and Understanding Infection Risks. Animals (Basel) 2025 Jul 16;15(14).
- Northcote HM, Wititkornkul B, Cutress DJ, Allen ND, Brophy PM, Wonfor RE, Morphew RM. A dominance of Mu class glutathione transferases within the equine tapeworm Anoplocephala perfoliata. Parasitology 2024 Mar;151(3):282-294.
- Matthews JB, Peczak N, Lightbody KL. The Use of Innovative Diagnostics to Inform Sustainable Control of Equine Helminth Infections. Pathogens 2023 Oct 11;12(10).
- Wititkornkul B, Hulme BJ, Tomes JJ, Allen NR, Davis CN, Davey SD, Cookson AR, Phillips HC, Hegarty MJ, Swain MT, Brophy PM, Wonfor RE, Morphew RM. Evidence of Immune Modulators in the Secretome of the Equine Tapeworm Anoplocephala perfoliata. Pathogens 2021 Jul 20;10(7).
- Tomczuk K, Kostro K, Szczepaniak KO, Grzybek M, Studzińska M, Demkowska-Kutrzepa M, Roczeń-Karczmarz M. Comparison of the sensitivity of coprological methods in detecting Anoplocephala perfoliata invasions. Parasitol Res 2014 Jun;113(6):2401-6.
- Getachew AM, Innocent G, Proudman CJ, Trawford A, Feseha G, Reid SW, Faith B, Love S. Equine cestodosis: a sero-epidemiological study of Anoplocephala perfoliata infection in Ethiopia. Vet Res Commun 2012 Jun;36(2):93-8.
- Veronesi F, Diaferia M, Fioretti DP. Anoplocephala perfoliata infestation and colics in horses. Vet Res Commun 2009 Sep;33 Suppl 1:161-3.
- Getachew M, Trawford A, Feseha G, Reid SW. Gastrointestinal parasites of working donkeys of Ethiopia. Trop Anim Health Prod 2010 Jan;42(1):27-33.
- Lyons ET, Tolliver SC, Collins SS. Prevalence of large endoparasites at necropsy in horses infected with Population B small strongyles in a herd established in Kentucky in 1966. Parasitol Res 2006 Jul;99(2):114-8.
- McAloon FM. Oribatid mites as intermediate hosts of Anoplocephala manubriata, cestode of the Asian elephant in India. Exp Appl Acarol 2004;32(3):181-5.
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