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Home / Equine Research Bank / Front Vet Sci / The effects of obesity and insulin dysregulation on mare rep...
Frontiers in veterinary science2023; 10; 1180622; doi: 10.3389/fvets.2023.1180622

The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review.

Abstract: Obesity is a growing welfare concern in modern equine populations and predisposes horses to disturbances in energy metabolism such as insulin dysregulation. However, equine metabolic syndrome has only been recognized in recent decades. Functioning energy metabolism is pivotal to normal body homeostasis and affects essentially all organ systems, including reproduction. Previous literature suggests that obesity has an effect not only on the reproductive processes in mares but also on offspring health, predisposing the offspring to later-onset orthopedic and metabolic problems. This review focuses on the effects of obesity, insulin dysregulation and hyperinsulinemia on the reproductive functions of mares and the implications on foal health before and after birth. The points of interest are the cyclicity and ovarian function, uterine environment, gestation, the postpartum period, and the newborn foal. The aim is to review the current state of knowledge, and identify outstanding questions that could stimulate future research. This topic is important not only from the equine industry and production perspective but is also relevant for the welfare of future populations and individuals.
Copyright © 2023 Hallman, Karikoski and Kareskoski.
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Publication Date: 2023-04-20 PubMed ID: 37152686PubMed Central: PMC10158983DOI: 10.3389/fvets.2023.1180622Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

The research article reviews the impact of obesity, insulin regulation issues, and hyperinsulinemia on the reproductive health of mares and its implications on foal health, from gestation to after birth.

Impact of Obesity and Insulin Dysregulation on Mares

  • The study explores the increasing issue of obesity in horses, which can lead to problems in energy metabolism such as insulin dysregulation. It highlights equine metabolic syndrome as a recently recognized condition in the equine populations and stresses that a functioning energy metabolism is essential for maintaining normal body homeostasis, impacting essentially all organ systems, including reproduction.
  • The article suggests previous research indications about obesity affecting not just the reproductive processes in mares, but also having impacts on the health of the offspring. Offspring of obese mares may have a higher predisposition to suffer from orthopedic and metabolic issues later on in their lives.

Reproductive Functions and Foal Health

  • Considering the impacts of obesity, insulin dysregulation, and hyperinsulinemia on the reproductive functions of mares, the study emphasizes the implications on foal health before and after birth.
  • There are several points of interest explored in the study, including cyclicity and ovarian function, uterine environment during pregnancy, the postpartum period, and the health of the newborn foal.

Aim and Importance of This Review

  • The aim of this review is providing insights into the current state of knowledge regarding obesity, energy metabolism disorders in mares and their implications on foal health.
  • This review also aims to identify unanswered questions in this field that can guide and stimulate future research studies.
  • The topic is not only important for the equine industry and production but is also valuable for the welfare of future horse populations and individuals.

Cite This Article

APA
Hallman I, Karikoski N, Kareskoski M. (2023). The effects of obesity and insulin dysregulation on mare reproduction, pregnancy, and foal health: a review. Front Vet Sci, 10, 1180622. https://doi.org/10.3389/fvets.2023.1180622

Publication

Frontiers in veterinary science
ISSN: 2297-1769
NlmUniqueID: 101666658
Country: Switzerland
Language: English
Volume: 10
Pages: 1180622
PII: 1180622

Researcher Affiliations

Hallman, Isa
  • Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Karikoski, Ninja
  • Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Kareskoski, Maria
  • Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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