The oxidant/antioxidant equilibrium in horses.
- Journal Article
- Review
Summary
The research article provides an overview of the role of oxidants and antioxidants in maintaining the body’s equilibrium and discusses how imbalance in this system can result in oxidative stress, especially in horses. It also outlines methods to evaluate this balance or stress in horses, and summarizes existing understanding about oxidative stress in equine medicine and exercise physiology.
Oxidants and Antioxidants
The article begins by explaining the role of oxidants and antioxidants in physiological and pathological conditions. Oxidants are usually produced by metabolic enzymes, inflammatory cells, and mitochondrial electron leakage.
- Oxidants play a crucial role in cellular redox regulation and under certain circumstances, they can stimulate pro-inflammatory conditions.
- Endogenous and exogenous antioxidants counterbalance oxidative processes
While both oxidants and antioxidants are indispensable to maintaining the body’s equilibrium, an imbalance between the two – either due to excessive oxidant generation or insufficient antioxidants – can lead to oxidative stress.
Evaluating Oxidant/Antioxidant Equilibrium in Horses
The research further explores how to assess the oxidant/antioxidant balance in horses. An understanding of this balance is crucial, as oxidative stress can have significant impacts on the health and performance of horses, especially in equine sports.
Oxidative Stress in Equine Medicine
Finally, the article summarizes our current knowledge of oxidative stress in the field of equine medicine and exercise physiology. This includes the potential implications of oxidative stress on the overall health of horses, as well as on their performance in athletic pursuits. Understanding of this balance and its impacts can facilitate the development of better care protocols and potentially reproductive performance enhancement strategies for horses.
Cite This Article
Publication
Researcher Affiliations
- Animal Physiology, Department for Veterinary Medicine, Faculty of Sciences, University of Namur, Belgium. nathalie.kirschvink@fundp.ac.be
MeSH Terms
- Animals
- Antioxidants / metabolism
- Horse Diseases / metabolism
- Horses
- Oxidants / metabolism