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The British veterinary journal1979; 135(4); 324-327; doi: 10.1016/s0007-1935(17)32833-6

The pH/log PCO2 buffer curve of horse blood.

Abstract: Samples of jugular venous blood from six horses were equilibrated with six oxygen and carbon dioxide gas mixtures of PCO2 between 28 and 54 mm Hg. In all six samples the correlations between the pH and the log PCO2 values were linear and highly significant, with r in all six samples greater than 0.985. It was concluded that the Astrup method for the determination of the acid-base status of the blood of horses is valid.
Publication Date: 1979-07-01 PubMed ID: 43762DOI: 10.1016/s0007-1935(17)32833-6Google Scholar: Lookup
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  • Journal Article

Summary

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The research article discusses the correlation between the pH and log PCO2 values of horse blood, and affirms the validity of the Astrup method in determining the acid-base balance status of horse blood.

Objective of the Research

The research was aimed at understanding the relationship between pH and log PCO2 values in horse blood. The study also sought to validate the Astrup method’s accuracy in determining the acid-base status of horse blood.

  • The researchers used samples from the jugular venous blood of six horses.
  • The blood samples were then equilibrated with six gas mixtures of oxygen and carbon dioxide.

Research Methodology

The methodology employed by the researchers involved equilibrating blood samples with different gas mixtures and recording the pH and log PCO2 values.

  • The gas mixtures used had a PCO2 between 28 and 54 mm Hg.
  • By recording the pH and log PCO2 values under these conditions, researchers were able to measure their correlation.

Findings of the Study

The findings indicated that there is a linear and highly significant correlation between pH and log PCO2 values in horse blood, with an r-value in all six samples greater than 0.985.

  • This indicates a near-perfect linear correlation between the two variables, signifying that they interact in a predictable manner.
  • Research results also supported the validity of the Astrup method in determining the acid-base status of horse blood.

Conclusion of the Research

The research concluded that the Astrup technique for determining the acid-base balance of horse blood is valid and reliable. The correlation between the pH and log PCO2 values further supports this.

  • The conclusions drawn from this research can be beneficial for veterinarians and scientists studying equine health and blood chemistry.
  • Further research could explore correlations in other animal species or try to identify the factors that influence pH and PCO2 interaction in horse blood.

Cite This Article

APA
Littlejohn A. (1979). The pH/log PCO2 buffer curve of horse blood. Br Vet J, 135(4), 324-327. https://doi.org/10.1016/s0007-1935(17)32833-6

Publication

ISSN: 0007-1935
NlmUniqueID: 0372554
Country: England
Language: English
Volume: 135
Issue: 4
Pages: 324-327

Researcher Affiliations

Littlejohn, A

    MeSH Terms

    • Animals
    • Carbon Dioxide / blood
    • Horses / blood
    • Hydrogen-Ion Concentration
    • Methods

    Citations

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