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The role of allergy in chronic pulmonary disease of horses.

Abstract: Twenty-five horses with chronic pulmonary disease were skin tested with allergenic extracts of 24 molds, 4 thermophilic actinomyces, barn dust, hay dust, soya-bean mill dust, and grain mill dust. The results were compared with those obtained on 25 normal horses. Between the 2 groups of horses, there was a highly significant difference in positive skin test results at 30 minutes and 4 hours.
Publication Date: 1979-02-01 PubMed ID: 571867
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  • Comparative Study
  • Journal Article

Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research investigates the potential role of allergies in chronic pulmonary disease in horses. By comparing skin test results between a group of 25 horses with chronic pulmonary disease and 25 normal horses, the researchers found a significant difference.

Objective of the Research

  • This study was conducted to evaluate the possibility that allergies, specifically to certain dust and mold types, contribute to chronic pulmonary disease in horses.

Methodology

  • Twenty-five horses already diagnosed with chronic pulmonary disease underwent skin testing using allergenic extracts derived from 24 different molds, 4 thermophilic actinomyces, barn dust, hay dust, soybean mill dust, and grain mill dust.
  • For a comparative analysis, a control group of 25 healthy horses were also subjected to the same skin test.
  • The response to the allergenic extracts was monitored at 30 minutes and 4 hours post-application to infer any potential allergic reaction.

Findings

  • Comparing skin test results between horses with chronic pulmonary disease and healthy horses, the researchers found a highly significant difference.
  • This suggests that the group of horses with chronic pulmonary disease displayed a heightened allergic reaction to certain allergenic extracts in comparison to the healthy group.
  • Although the specific allergens causing this significant difference are not mentioned in the abstract, the overall results indicate a potential link between allergies and chronic pulmonary disease in horses.

Research Implications

  • The findings of this research can have substantial implications in equine health and the veterinary field. Recognizing the role that allergies play in chronic pulmonary diseases could open a new avenue for disease management and treatment in horses.
  • Understanding the potential allergic triggers could lead to preventative measures that reduce the onset risk of chronic pulmonary disease, enhancing horse welfare.

Cite This Article

APA
Halliwell RE, Fleischman JB, Mackay-Smith M, Beech J, Gunson DE. (1979). The role of allergy in chronic pulmonary disease of horses. J Am Vet Med Assoc, 174(3), 277-281.

Publication

ISSN: 0003-1488
NlmUniqueID: 7503067
Country: United States
Language: English
Volume: 174
Issue: 3
Pages: 277-281

Researcher Affiliations

Halliwell, R E
    Fleischman, J B
      Mackay-Smith, M
        Beech, J
          Gunson, D E

            MeSH Terms

            • Acremonium / immunology
            • Animals
            • Antigens, Bacterial
            • Antigens, Fungal
            • Dust
            • Edible Grain
            • Horse Diseases / etiology
            • Horse Diseases / immunology
            • Horses
            • Lung Diseases, Obstructive / etiology
            • Lung Diseases, Obstructive / immunology
            • Lung Diseases, Obstructive / veterinary
            • Micromonosporaceae / immunology
            • Respiratory Hypersensitivity / immunology
            • Respiratory Hypersensitivity / veterinary
            • Rhizopus / immunology
            • Skin Tests
            • Soybeans

            Citations

            This article has been cited 5 times.
            1. Lo Feudo CM, Stucchi L, Alberti E, Conturba B, Zucca E, Ferrucci F. Intradermal Testing Results in Horses Affected by Mild-Moderate and Severe Equine Asthma.. Animals (Basel) 2021 Jul 13;11(7).
              doi: 10.3390/ani11072086pubmed: 34359214google scholar: lookup
            2. Tesarowski DB, Viel L, McDonell WN, Newhouse MT. The rapid and effective administration of a beta 2-agonist to horses with heaves using a compact inhalation device and metered-dose inhalers.. Can Vet J 1994 Mar;35(3):170-3.
              pubmed: 8055432
            3. Matthews AG, Imlah P, McPherson EA. A reagin-like antibody in horse serum: 1. Occurrence and some biological properties.. Vet Res Commun 1983 Jan;6(1):13-23.
              doi: 10.1007/BF02214891pubmed: 6868343google scholar: lookup
            4. Collins M, Algers B. Effects of stable dust on farm animals--a review.. Vet Res Commun 1986 Nov;10(6):415-28.
              doi: 10.1007/BF02214005pubmed: 3541364google scholar: lookup
            5. Soma LR, Beech J, Gerber NH Jr. Effects of cromolyn in horses with chronic obstructive pulmonary disease.. Vet Res Commun 1987;11(4):339-51.
              doi: 10.1007/BF00346192pubmed: 3118560google scholar: lookup