The use of nutraceuticals for osteoarthritis in horses.
Abstract: In horses, lameness is often attributable to some degree of osteoarthritis (OA), a complex disease process that is highlighted by eventual degradation of articular cartilage. Conventional therapies for OA in horses are designed to relieve pain and discomfort and often include pharmacologic intervention with nonsteroidal anti-inflammatory drugs or intra-articular steroids. Oral administration of nutraceutical products to the horse is common and easy and is perceived to be a benign treatment for OA in horses. The main goal for use of nutraceuticals is to use them in OA cases to attempt to lower the dose of other drugs that are more problematic while potentially preventing further degradation (disease or structure modifying). This article attempts to define a nutraceutical, identifies areas that need to be considered when these products are used, and describes the known scientific effects of the most common compounds contained in currently available equine nutraceuticals.
Publication Date: 2005-11-22 PubMed ID: 16297722DOI: 10.1016/j.cveq.2005.08.004Google Scholar: Lookup
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Summary
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This research focuses on the usage of nutraceuticals, or nutrition-based supplements, to reduce pain and potentially slow the degradation associated with osteoarthritis in horses. This practice aims to lower the need for other problematic drugs.
Introduction to the Study
The study addresses a common health issue in horses, osteoarthritis (OA), which often leads to lameness. Conventional methods for managing OA typically involve the use of nonsteroidal anti-inflammatory drugs or intra-articular steroids to lessen discomfort. However, a rise in the administration of nutraceutical products, which are usually given orally, represents an emerging alternative method for treating OA in horses.
Understanding Nutraceuticals
- The research takes a closer look at nutraceutical products and tries to define them within the context of equine health. Nutraceuticals encompass any product derived from food sources purported to offer extra health benefits, potentially reducing disease risks or promoting better health.
- Nutraceuticals are seen as a benign treatment, perceived to be safe due to their natural, nutrition-based origins.
The Role of Nutraceuticals in OA Treatment
- The primary goal of using nutraceuticals in OA cases is to diminish the required doses of other, more troublesome drugs. Reduction in the use of these other, potentially harmful medications could be beneficial for the overall health of the horse.
- Moreover, nutraceuticals could possibly prevent further degradation in the joint, serving a disease-modifying or structure-modifying role.
Evaluation of Common Nutraceutical Compounds
- The research evaluates the known scientific effects of the most common compounds found in equine nutraceuticals available on the market.
- Different compounds could have varying effects, and understanding these effects can help in the strategic use of nutraceuticals in managing equine OA.
Considerations in the Use of Nutraceuticals
- The study emphasizes several factors that need to be taken into account when applying nutraceuticals in equine OA cases.
- These factors likely involve considerations about the specific health status of the horse, the individual compounds in the nutraceuticals, and the coordination with other treatments currently being applied.
Cite This Article
APA
Trumble TN.
(2005).
The use of nutraceuticals for osteoarthritis in horses.
Vet Clin North Am Equine Pract, 21(3), 575-vi.
https://doi.org/10.1016/j.cveq.2005.08.004 Publication
Researcher Affiliations
- Department of Large Animal Clinical Sciences, University of Florida, College of Veterinary Medicine, PO Box 100136, Gainesville, FL 32610, USA. trumblet@mail.vetmed.ufl.edu
MeSH Terms
- Animals
- Anti-Inflammatory Agents / therapeutic use
- Cartilage, Articular / physiopathology
- Chondroitin Sulfates / therapeutic use
- Complementary Therapies / methods
- Complementary Therapies / veterinary
- Drug Therapy, Combination
- Glucosamine / therapeutic use
- Horse Diseases / drug therapy
- Horse Diseases / pathology
- Horses
- Lameness, Animal / drug therapy
- Lameness, Animal / pathology
- Osteoarthritis / drug therapy
- Osteoarthritis / pathology
- Osteoarthritis / veterinary
- Phytotherapy / methods
- Phytotherapy / veterinary
- Safety
- Treatment Outcome
Citations
This article has been cited 6 times.- Finno CJ. Veterinary Pet Supplements and Nutraceuticals. Nutr Today 2020 Mar-Apr;55(2):97-101.
- Gugliandolo E, Barbagallo A, Peritore AF, Cuzzocrea S, Crupi R. Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report. Animals (Basel) 2020 Aug 21;10(9).
- Battaglia B, Angelone M, Vera E, Basini G, Bussolati S, Paci M, Bue MD, Aldigeri R, Grolli S, Quintavalla F, Ramoni R. Clinical Effects of the Extract of the Seeds of the Indian Celery-Apium Graveolens-In Horses Affected by Chronic Osteoarthritis. Animals (Basel) 2019 Aug 20;9(8).
- Axmann S, Hummel K, Nöbauer K, Razzazi-Fazeli E, Zitterl-Eglseer K. Pharmacokinetics of harpagoside in horses after intragastric administration of a Devil's claw (Harpagophytum procumbens) extract. J Vet Pharmacol Ther 2019 Jan;42(1):37-44.
- Vendruscolo CDP, Moreira JJ, Seidel SRT, Fülber J, Neuenschwander HM, Bonagura G, Agreste FR, Baccarin RYA. Effects of medical ozone upon healthy equine joints: Clinical and laboratorial aspects. PLoS One 2018;13(5):e0197736.
- van de Water E, Oosterlinck M, Dumoulin M, Korthagen NM, van Weeren PR, van den Broek J, Everts H, Pille F, van Doorn DA. The preventive effects of two nutraceuticals on experimentally induced acute synovitis. Equine Vet J 2017 Jul;49(4):532-538.
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