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Veterinary journal (London, England : 1997)2013; 197(3); 570-577; doi: 10.1016/j.tvjl.2013.04.018

Therapeutic use of stem cells in horses: which type, how, and when?

Abstract: Stem cells are commonly used in equine practice to treat musculoskeletal disorders including tendonitis, osteoarthritis, and more recently laminitis. As the field of regenerative medicine continues to advance, equine practitioners need contemporary information regarding the choice of stem cell type and recommendations regarding clinical implementation of stem cell therapies. Clinicians must also be aware of the limitation in current knowledge regarding stem cells, and the impending regulatory laws that may limit the use of equine stem cells in clinical patients.
Publication Date: 2013-06-15 PubMed ID: 23778257DOI: 10.1016/j.tvjl.2013.04.018Google Scholar: Lookup
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Summary

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This research article provides an update on the use of stem cells for treating musculoskeletal issues in horses, discuss the types of stem cells best suited for such therapies, the best way and time to apply these therapies, and current limitations in knowledge and regulations.

Stem Cells in Equine Treatment

The research paper elaborates on the increasing use of stem cells in the treatment of musculoskeletal disorders in horses. Some of the conditions treated using stem cell therapies include:

  • Tendonitis: This is a type of inflammation in the tendons that often result from overuse, injury, or ageing. Stem cells have been used to foster healing and tissue repair in affected tendons.
  • Osteoarthritis: This degenerative joint condition is another area where stem cells have been effectively used. They help in repairing and regenerating damaged joint tissues.
  • Laminitis: This is a severe and painful condition affecting the horse’s hooves. The recent application of stem cell treatment in such cases has shown promising results.

Evolving Stem Cell Types in Therapy

The paper draws attention towards the need for equine practitioners to maintain up-to-date information on the suitable types of stem cells for different treatments. The type of stem cells are selected based on:

  • The nature of the disorder
  • The expected outcome of the treatment
  • The current understanding and research on the specific type of stem cell.

Method of Stem Cell Therapies Application

A notable point spoken about in the paper is the method and time of stem cell therapy application. These factors influence the effectiveness of the treatment and depend on:

  • The specific physical condition of the horse
  • Progression and severity of the disorder
  • The type of stem cell being used
  • Recent advancements and understanding in the field of regenerative medicine

Current Knowledge Limitations and Legislative Constraints

The paper finally highlights the current limitations in knowledge regarding the effective therapeutic use of stems cells in the equine industry. It also brings attention to impending regulatory laws that may constrain the use of equine stem cells in clinical patients.
These obstacles need to be overcome through ongoing research and constructive dialogue with policy-making bodies for the effective, legal, and ethical application of stem cell therapies.

Cite This Article

APA
Schnabel LV, Fortier LA, McIlwraith CW, Nobert KM. (2013). Therapeutic use of stem cells in horses: which type, how, and when? Vet J, 197(3), 570-577. https://doi.org/10.1016/j.tvjl.2013.04.018

Publication

ISSN: 1532-2971
NlmUniqueID: 9706281
Country: England
Language: English
Volume: 197
Issue: 3
Pages: 570-577

Researcher Affiliations

Schnabel, Lauren V
  • Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA. Electronic address: lvs3@cornell.edu.
Fortier, Lisa A
    McIlwraith, C Wayne
      Nobert, Karl M

        MeSH Terms

        • Animals
        • Horse Diseases / therapy
        • Horses
        • Stem Cell Transplantation / veterinary

        Citations

        This article has been cited 29 times.