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Home / Equine Research Bank / J Fungi (Basel) / Therapy of Non-Dermatophytic Mycoses in Animals.
Journal of fungi (Basel, Switzerland)2018; 4(4); doi: 10.3390/jof4040120

Therapy of Non-Dermatophytic Mycoses in Animals.

Abstract: This review focuses on aspects of antimycotic therapy specific to veterinary medicine. In the first part, drug availability, limited mostly by economic consideration but also by clinical applicability and specific adverse effects, is described for polyenes, 5 fluorocytosine, azoles, echinocandins and terbinafine. In the second part, current knowledge and experience in the treatment of selected fungal infections are overviewed. These mycoses include disseminated mold infections in small animals (dogs and cats) and avian species, upper respiratory tract infections of small animals (sino-nasal and sino-orbital aspergillosis) and horses (guttural pouch mycosis), eumycetoma, infections caused by dimorphic fungi, (blastomycosis, histoplasmosis, coccidioidomycosis, paracoccidioidomycosis and sporothrichosis) and by yeasts and yeast-like microorganism (Cryptococcus spp. and Malassezia pachydermatis).
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Publication Date: 2018-10-30 PubMed ID: 30380772PubMed Central: PMC6308939DOI: 10.3390/jof4040120Google Scholar: Lookup
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Summary

This research summary has been generated with artificial intelligence and may contain errors and omissions. Refer to the original study to confirm details provided. Submit correction.

This research article discusses the treatment of non-dermatophytic fungal infections in animals with different antifungal drugs. It gives an overview on the availability and limitations of these drugs and specifically discusses their uses in treating a range of fungal diseases in different pets and farm animals.

Antifungal Drug Availability and Limitations

  • The researchers begin by describing the availability of antifungal treatment options for animals. These include polyenes, 5 fluorocytosine, azoles, echinocandins, and terbinafine. Each class of drugs have their distinct pros and cons.
  • Economic considerations are a major factor determining the availability of these drugs. In many cases, the high cost of antifungal medications may restrict its access to veterinary practices.
  • In addition to the financial aspect, clinical applicability – how suitable a drug is for treating a particular infection in a certain species – also limits the use of some antifungal drugs.
  • Lastly, the authors suggest that potential adverse effects are a further limitation that veterinary practitioners should take into account while selecting a treatment method.

Treatment of Specific Fungal Infections

  • The second part of the study focuses on the treatment of specific fungal infections observed in different animals such as dogs, cats, birds, and horses.
  • Disseminated mold infections, a type of fungal infection affecting multiple areas or systems of the body, are examined in small animals and avian species.
  • The article discusses the treatment of upper respiratory tract infections of small animals caused by fungi, specifically those affecting sinuses and orbit (eye socket), and a similar condition in horses called guttural pouch mycosis.
  • Eumycetoma, a specific type of fungal infection affecting the skin, is discussed, along with infections caused by dimorphic fungi—organisms that can exist in two forms.
  • The article also gives details about infections caused by certain types of yeasts and yeast-like organisms.

Conclusion

The authors conclude that understanding the accessibility and limitations of antifungal drugs is crucial in the veterinary field. The article provides valuable information about treating specific fungal infections across different species, which can assist veterinarians in choosing an effective treatment method for their patients.

Cite This Article

APA
Elad D. (2018). Therapy of Non-Dermatophytic Mycoses in Animals. J Fungi (Basel), 4(4). https://doi.org/10.3390/jof4040120

Publication

Journal of fungi (Basel, Switzerland)
ISSN: 2309-608X
NlmUniqueID: 101671827
Country: Switzerland
Language: English
Volume: 4
Issue: 4

Researcher Affiliations

Elad, Daniel
  • Department of Clinical Bacteriology and Mycology, The Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel. daniel.elad@gmail.com.

Conflict of Interest Statement

The authors declare no conflict of interest.

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Citations

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