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Thyroid hyperplasia and musculoskeletal deformity in a standardbred filly in Ontario.

Abstract: Thyroid hyperplasia and musculoskeletal deformity, described in foals in western Canada, has not been recognized as a common cause of neonatal foal mortality in Ontario. A case is reported from Ontario, with clinical and histopathological findings consistent with the syndrome described in western Canada. Résumé — Hyperplasie thyroïdienne et déformation musculosquelettique chez une pouliche Standardbred. L’hyperplasie de la thyroïde et la déformation musculosquelettique, décrites chez les poulains dans l’ouest du Canada, n’a pas été reconnue comme cause fréquente de mortalité néonatale chez les poulains en Ontario. Un cas est rapporté en Ontario et les trouvailles cliniques et histopathologiques sont compatibles avec le syndrome décrit dans l’ouest du Canada. (Traduit par Docteur André Blouin)
Publication Date: 2004-06-23 PubMed ID: 15206593PubMed Central: PMC548628
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Summary

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This research reports a case of thyroid hyperplasia and musculoskeletal deformity, previously reported mainly in western Canada, in a foal in Ontario, marking its first occurrence in that region.

Overview of the Research

This article is a case report on a previously uncommon health syndrome found in a standardbred filly in Ontario. The syndrome, characterized by thyroid hyperplasia and musculoskeletal deformity, has been reported in foals in western Canada. However, it is not recognized as a common cause of neonatal foal mortality in Ontario. This paper brings attention to the syndrome’s occurrence in Ontario, generating implications for veterinarians, horse breeders, and animal health researchers in the region.

Thyroid Hyperplasia and Musculoskeletal Deformity in Foals

  • The detected syndrome in the foal includes two main conditions – thyroid hyperplasia and musculoskeletal deformity. Thyroid hyperplasia denotes an abnormal increase in cells in the thyroid gland, potentially impacting the metabolism of the animal. Musculoskeletal deformity refers to the deformities in the skeletal and muscular systems, which can impact the physical capabilities of the foal.
  • It is crucial to note that this syndrome has not been generally attributed to foal death within the Ontario region. Thus, this case brings new insights into the veterinary medical field within the area.

Clinical and Histopathological Findings

  • The case report includes a thorough investigation of the foal, including clinical and histopathological examinations. These findings provide a comprehensive understanding of the syndrome as it appears in the foal.
  • The clinical findings likely document the visible symptoms and abnormalities on the foal, while the histopathological findings potentially point to changes and anomalies at a tissue and cellular level, obtained by microscopic examination of the affected body parts.
  • These findings are consistent with those of a similar syndrome described in western Canada, indicating that the same syndrome has now been found in Ontario.

Implications of the Research

  • The reporting of this unique case in Ontario can create awareness among veterinary professionals and horse breeders about the existence of this syndrome, leading to its early detection and management. It also provides regional figures with comparative data from other regions, in this case, western Canada.
  • This case report can also stimulate further research to comprehend why this syndrome has appeared in Ontario and if environmental or other factors could have facilitated its occurrence.

Cite This Article

APA
Gawrylash SK. (2004). Thyroid hyperplasia and musculoskeletal deformity in a standardbred filly in Ontario. Can Vet J, 45(5), 424-426.

Publication

ISSN: 0008-5286
NlmUniqueID: 0004653
Country: Canada
Language: English
Volume: 45
Issue: 5
Pages: 424-426

Researcher Affiliations

Gawrylash, Sally K
  • Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1.

MeSH Terms

  • Animals
  • Animals, Newborn / abnormalities
  • Congenital Abnormalities / veterinary
  • Fatal Outcome
  • Female
  • Horses / abnormalities
  • Horses / embryology
  • Hyperplasia / pathology
  • Hyperplasia / veterinary
  • Musculoskeletal Abnormalities / pathology
  • Musculoskeletal Abnormalities / veterinary
  • Musculoskeletal System / embryology
  • Musculoskeletal System / pathology
  • Ontario
  • Syndrome
  • Thyroid Gland / embryology
  • Thyroid Gland / pathology

References

This article includes 10 references
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  10. Doig B. Nitrates and Nitrate-Nitrite Poisoning.. Saskatchewan Agriculture, Food and Rural Revitalization 2001.

Citations

This article has been cited 1 times.
  1. Ibrahim RS, El-Mezayen NS, Khairy A, Zaatout HH, Hammoda HM, Metwally AM. Biologically-Guided Isolation of Natural Lead Antithyroid Drug from Medicago sativa L. Sprouts and Its Toxic Profile in Comparison with Propylthiouracil. J Food Drug Anal 2020 Sep 15;28(3):407-448.
    doi: 10.38212/2224-6614.1242pubmed: 35696097google scholar: lookup